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Pnpla2 elisa kit :: Mouse Patatin-like phospholipase domain-containing protein 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2881428 Pnpla2 elisa kit
Unit / Price
48-Strip-Wells  /  $420 +1 FREE 8GB USB
96-Strip-Wells  /  $560 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,445 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,520 +5 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Patatin-like phospholipase domain-containing protein 2 (Pnpla2), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Patatin-like phospholipase domain-containing protein 2 ELISA Kit

 Product Synonym Names    Patatin-like phospholipase domain-containing protein 2; Adipose triglyceride lipase; Desnutrin; Pnpla2; Atgl; 3.1.1.3
 Product Gene Name   

Pnpla2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q8BJ56
 Species Reactivity    Mouse
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 Assay Type    Sandwich
 Detection Range    0.156-10 ng/ml
 Sensitivity    0.086 ng/mL
 Intra-Assay CV    <=4.8%
 Inter-Assay CV    <=7.5%
 Recovery    92%
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Pnpla2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Pnpla2 purchase    MBS2881428 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Patatin-like phospholipase domain-containing protein 2 (Pnpla2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156-10 ng/ml in biological research samples containing Pnpla2, with an estimated sensitivity of 0.086 ng/mL. The ELISA analytical biochemical technique of the MBS2881428 kit is based on Pnpla2 antibody-Pnpla2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Pnpla2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Pnpla2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for Pnpla2. It may not necessarily be applicable to this product.
 NCBI GI #    254826780
 NCBI GeneID    66853
 NCBI Accession #    NP_001157161.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001163689.1 [Other Products]
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 UniProt Primary Accession #    Q8BJ56 [Other Products]
 UniProt Secondary Accession #    O89080; Q05BJ0; Q3UD97; Q643S0; Q6P234; Q9D1Q9; Q9DCF6 [Other Products]
 UniProt Related Accession #    Q8BJ56 [Other Products]
 Molecular Weight    47,877 Da
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 NCBI Official Full Name    patatin-like phospholipase domain-containing protein 2 isoform 1
 NCBI Official Synonym Full Names    patatin-like phospholipase domain containing 2
 NCBI Official Symbol    Pnpla2 [Similar Products]
 NCBI Official Synonym Symbols   
Atgl; TTS-2.2; 0610039C21Rik; 1110001C14Rik
[Similar Products]
 NCBI Protein Information    patatin-like phospholipase domain-containing protein 2
 UniProt Protein Name    Patatin-like phospholipase domain-containing protein 2
 UniProt Synonym Protein Names   
Adipose triglyceride lipase; Desnutrin
 Protein Family    Patatin-like phospholipase domain-containing protein
 UniProt Gene Name    Pnpla2 [Similar Products]
 UniProt Synonym Gene Names    Atgl [Similar Products]
 UniProt Entry Name    PLPL2_MOUSE
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 UniProt Comments for Pnpla2    PNPLA2: the rate-limiting lipolytic enzyme in mammals, flies, and yeast. Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Upregulated by exercise training in human skeletal muscle. Has acylglycerol transacylase activity. May act coordinately with HSL within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion. Interacting with ABHD5 stimulates its triglyceride hydrolase activity. Despite a colocalization in lipid droplets, it probably does not interact with perilipin. Transcriptionally regulated by FOXO1A. Defects cause neutral lipid storage disease (NLSD), an autosomal recessive disorder characterized by the excessive accumulation of neutral lipids in multiple tissues. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.1.3; Lipase; Membrane protein, integral

Cellular Component: cytosol; integral to membrane; lipid particle; membrane; plasma membrane

Molecular Function: hydrolase activity; protein binding; triacylglycerol lipase activity

Biological Process: lipid catabolic process; lipid metabolic process; metabolic process; sequestering of lipid; triacylglycerol catabolic process
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 Research Articles on Pnpla2    1. A role for Atgl in kidney lipolysis:fasting up-regulates Atgl levels and phosphorylation in mouse kidney.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Pnpla2 elisa kitPathways associated with Pnpla2 elisa kit
 Reference Product  PubMed Publications
 Abhd5 elisa kit  >34 publications with Pnpla2 and Abhd5
 Lpl elisa kit  >6 publications with Pnpla2 and Lpl
 Dgat1 elisa kit  >6 publications with Pnpla2 and Dgat1
 Plin5 elisa kit  >4 publications with Pnpla2 and Plin5
 Plin1 elisa kit  >4 publications with Pnpla2 and Plin1
 Mgll elisa kit  >3 publications with Pnpla2 and Mgll
 Lpin1 elisa kit  >3 publications with Pnpla2 and Lpin1
 Dgat2 elisa kit  >2 publications with Pnpla2 and Dgat2
 Lipg elisa kit  >1 publications with Pnpla2 and Lipg
 Products by Pathway  Pathway Diagram
 Acyl Chain Remodeling Of DAG And TAG Pathway antibodies  Acyl Chain Remodeling Of DAG And TAG Pathway Diagram
 Acylglycerol Degradation Pathway antibodies  Acylglycerol Degradation Pathway Diagram
 Acylglycerol Degradation Pathway antibodies  Acylglycerol Degradation Pathway Diagram
 Fatty Acid Beta Oxidation Pathway antibodies  Fatty Acid Beta Oxidation Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerolipid Metabolism Pathway antibodies  Glycerolipid Metabolism Pathway Diagram
 Glycerophospholipid Biosynthesis Pathway antibodies  Glycerophospholipid Biosynthesis Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
Diseases associated with Pnpla2 elisa kitOrgans/Tissues associated with Pnpla2 elisa kit
 Disease Name  Pubmed Publications
 Fatty Liver Antibodies  >40 publications with Pnpla2 and Fatty Liver
 Insulin Resistance Antibodies  >29 publications with Pnpla2 and Insulin Resistance
 Liver Diseases Antibodies  >22 publications with Pnpla2 and Liver Diseases
 Neutral Lipid Storage Disease with Myopathy Antibodies  >21 publications with Pnpla2 and Neutral Lipid Storage Disease with Myopathy
 Heart Diseases Antibodies  >14 publications with Pnpla2 and Heart Diseases
 Inflammation Antibodies  >13 publications with Pnpla2 and Inflammation
 Non-alcoholic Fatty Liver Disease Antibodies  >11 publications with Pnpla2 and Non-alcoholic Fatty Liver Disease
 Necrosis Antibodies  >9 publications with Pnpla2 and Necrosis
 Hypertrophy Antibodies  >5 publications with Pnpla2 and Hypertrophy
 Atherosclerosis Antibodies  >5 publications with Pnpla2 and Atherosclerosis
 Organ/Tissue Name  Pubmed Publications
 Adipose Tissue Antibodies  >68 publications with Pnpla2 and Adipose Tissue
 Muscle Antibodies  >46 publications with Pnpla2 and Muscle
 Liver Antibodies  >44 publications with Pnpla2 and Liver
 Connective Tissue Antibodies  >44 publications with Pnpla2 and Connective Tissue
 Heart Antibodies  >19 publications with Pnpla2 and Heart
 Eye Antibodies  >15 publications with Pnpla2 and Eye
 Skin Antibodies  >10 publications with Pnpla2 and Skin
 Brain Antibodies  >7 publications with Pnpla2 and Brain
 Artery Antibodies  >5 publications with Pnpla2 and Artery
 Kidney Antibodies  >5 publications with Pnpla2 and Kidney
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