NP_035275.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
49,715 Da
NCBI Official Full Name
peroxisome proliferator-activated receptor delta
NCBI Official Synonym Full Names
peroxisome proliferator activator receptor delta
NCBI Official Synonym Symbols
NUC1; NUC-1; Nr1c2; Pparb; PPAR[b]; Pparb/d; PPAR-beta; PPARdelta; PPAR-delta [Similar Products]
NCBI Protein Information
peroxisome proliferator-activated receptor delta; PPARdelta/beta; nuclear hormone receptor 1; nuclear receptor subfamily 1 group C member 2; Peroxisome proliferator-activated receptor beta
UniProt Protein Name
Peroxisome proliferator-activated receptor delta
UniProt Synonym Protein Names
Nuclear hormone receptor 1; NUC1; Nuclear receptor subfamily 1 group C member 2; Peroxisome proliferator-activated receptor beta; PPAR-beta
UniProt Synonym Gene Names
UniProt Entry Name
PPARD_MOUSE
UniProt Comments for PPAR-beta
PPAR-delta: Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by a ligand. Belongs to the nuclear hormone receptor family. NR1 subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Nuclear receptor; DNA-binding
Cellular Component: nucleus
Molecular Function: ligand-dependent nuclear receptor activity; zinc ion binding; prostacyclin receptor activity; metal ion binding; transcription coactivator activity; enzyme activator activity; drug binding; retinoid X receptor binding; NF-kappaB binding; DNA binding; sequence-specific DNA binding; protein heterodimerization activity; steroid hormone receptor activity; fatty acid binding; lipid binding; transcription factor activity
Biological Process: transcription from RNA polymerase II promoter; positive regulation of catalytic activity; proteoglycan metabolic process; epidermis development; wound healing; negative regulation of smooth muscle cell proliferation; regulation of fat cell differentiation; positive regulation of transcription, DNA-dependent; negative regulation of collagen biosynthetic process; positive regulation of epidermis development; negative regulation of smooth muscle cell migration; negative regulation of transcription from RNA polymerase II promoter; positive regulation of vasodilation; vitamin A metabolic process; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; axon ensheathment; cell differentiation; negative regulation of epithelial cell proliferation; placenta development; intracellular receptor-mediated signaling pathway; transcription, DNA-dependent; positive regulation of insulin secretion; keratinocyte proliferation; keratinocyte migration; cell-substrate adhesion; regulation of cell proliferation; phospholipid biosynthetic process; positive regulation of phosphoinositide 3-kinase cascade; regulation of transcription from RNA polymerase II promoter; cell proliferation; G-protein coupled receptor protein signaling pathway; negative regulation of inflammatory response; mRNA transcription; fatty acid oxidation; steroid hormone mediated signaling; negative regulation of cell growth; lipid metabolic process; anagen; cellular process; regulation of insulin secretion; embryo implantation; negative regulation of apoptosis
Research Articles on PPAR-beta
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Pathways associated with PPAR-beta elisa kit
Diseases associated with PPAR-beta elisa kit
Organs/Tissues associated with PPAR-beta elisa kit
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