NP_061358.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
28,827 Da
NCBI Official Full Name
phosphoglycerate mutase 2
NCBI Official Synonym Full Names
phosphoglycerate mutase 2
NCBI Protein Information
phosphoglycerate mutase 2
UniProt Protein Name
Phosphoglycerate mutase 2
UniProt Synonym Protein Names
BPG-dependent PGAM 2; Muscle-specific phosphoglycerate mutase; Phosphoglycerate mutase isozyme M; PGAM-M
UniProt Synonym Gene Names
UniProt Entry Name
PGAM2_MOUSE
UniProt Comments for Pgam2
PGAM2: Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity. Defects in PGAM2 are the cause of glycogen storage disease type 10 (GSD10). A metabolic disorder characterized by myoglobinuria, increased serum creatine kinase levels, decreased phosphoglycerate mutase activity, myalgia, muscle pain, muscle cramps and excercise intolerance. Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
Protein type: EC 5.4.2.4; EC 5.4.2.11; Phosphatase (non-protein); EC 3.1.3.13; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Isomerase
Cellular Component: cytosol; nucleus
Molecular Function: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity; bisphosphoglycerate mutase activity; bisphosphoglycerate phosphatase activity; catalytic activity; cofactor binding; hydrolase activity; intramolecular transferase activity, phosphotransferases; isomerase activity; phosphoglycerate mutase activity; protein binding
Biological Process: gluconeogenesis; glycolysis; metabolic process; Notch signaling pathway; regulation of pentose-phosphate shunt; response to inorganic substance; response to mercury ion; striated muscle contraction
Research Articles on Pgam2
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Products associated with Pgam2 elisa kit
Pathways associated with Pgam2 elisa kit
Diseases associated with Pgam2 elisa kit
Organs/Tissues associated with Pgam2 elisa kit
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