View our list of available Coronavirus (COVID-19, SARS-CoV-2, 2019-nCOV) antibodies, recombinant proteins, ELISA Kits... Options Full Datasheet Printer Friendly Datasheet Prepare for Printing Full Datasheet Printer Friendly Datasheet Prepare for Printing Have Questions? Ask Us! Request A Quote Today! Add To Compare List PTGS1 elisa kit :: Mouse Prostaglandin Endoperoxide Synthase 1 ELISA Kit Catalog # MBS720727 Unit / Price 48-Strip-Wells / $495 +1 FREE 8GB USB 96-Strip-Wells / $700 +1 FREE 8GB USB 5x96-Strip-Wells / $3,105 +3 FREE 8GB USB 10x96-Strip-Wells / $5,865 +7 FREE 8GB USB Product Name Product Info Accession #s Product Desc Diseases/Tissues/Pathways Applications References Product Name Prostaglandin Endoperoxide Synthase 1 (PTGS1), ELISA Kit Full Product Name Mouse Prostaglandin Endoperoxide Synthase 1 ELISA Kit Product Gene Name PTGS1 elisa kit[Similar Products] Research Use Only For Research Use Only. Not for use in diagnostic procedures. TOP Sample Manual Insert Download Sample PDF Manual View Sample PDF Manual OMIM 176805 Species Reactivity Mouse Samples Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate Assay Type Competitive Detection Range 100-2500pg/mL Sensitivity 1.0pg/mL Intended Uses This PTGS1 ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of Mouse PTGS1. This ELISA kit for research use only, not for therapeutic applications! Preparation and Storage Store all reagents at 2-8 degree C. Sample Preparation We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team ISO Certification Manufactured in an ISO 13485:2016 Certified Laboratory. Product Note Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details. Other Notes Small volumes of PTGS1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply. Searchable Terms for PTGS1 purchase MBS720727 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Prostaglandin Endoperoxide Synthase 1 (PTGS1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PTGS1. The ELISA analytical biochemical technique of the MBS720727 kit is based on PTGS1 antibody-PTGS1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PTGS1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PTGS1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%). TOP Related Product Information for PTGS1 elisa kit Principle of the assay: PTGS1 ELISA kit applies the quantitative sandwich enzyme immunoassay technique. The microtiter plate has been pre-coated with a monoclonal antibody specific for PTGS1. Standards or samples are then added to the microtiter plate wells and PTGS1 if present, will bind to the antibody pre-coated wells. In order to quantitatively determine the amount of PTGS1 present in the sample, a standardized preparation of horseradish peroxidase (HRP)-conjugated polyclonal antibody, specific for PTGS1 are added to each well to “sandwich” the PTGS1 immobilized on the plate. The microtiter plate undergoes incubation, and then the wells are thoroughly washed to remove all unbound components. Next, substrate solutions are added to each well. The enzyme (HRP) and substrate are allowed to react over a short incubation period. Only those wells that contain PTGS1 and enzyme-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The PTGS1 concentration in each sample is interpolated from this standard curve. Typical Testing Data/Standard Curve (for reference only) of PTGS1 elisa kit TOP Sample Manual Insert of MBS720727. NCBI/Uniprot data below describe general gene information for PTGS1. It may not necessarily be applicable to this product. NCBI GI # 17017287 NCBI GeneID 5742 NCBI Accession # AAL33601.1 [Other Products] UniProt Secondary Accession # Q15122; Q3HY28; Q3HY29; Q5T7T6; Q5T7T7; Q5T7T8; A8K1V7; B4DHQ2; B4E2S5[Other Products] UniProt Related Accession # P23219[Other Products] Molecular Weight 72,010 Da TOP NCBI Official Full Name prostaglandin-endoperoxide synthase 1 NCBI Official Synonym Full Names prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) NCBI Official Symbol PTGS1 [Similar Products] NCBI Official Synonym Symbols COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1 [Similar Products] NCBI Protein Information prostaglandin G/H synthase 1; PGH synthase 1; cyclooxygenase-1; prostaglandin H2 synthase 1 UniProt Protein Name Prostaglandin G/H synthase 1 UniProt Synonym Protein Names Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1 Protein Family Prostaglandin G/H synthase UniProt Gene Name PTGS1 [Similar Products] UniProt Synonym Gene Names COX1; COX-1; PGH synthase 1; PGHS-1; PHS 1 [Similar Products] UniProt Entry Name PGH1_HUMAN TOP NCBI Summary for PTGS1 This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] TOP UniProt Comments for PTGS1 COX-1: May play an important role in regulating or promoting cell proliferation in some normal and neoplastically transformed cells. Homodimer. Belongs to the prostaglandin G/H synthase family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Lipid Metabolism - arachidonic acid; Oxidoreductase; EC 1.14.99.1Chromosomal Location of Human Ortholog: 9q32-q33.3Cellular Component: endoplasmic reticulum membrane; photoreceptor outer segment; intracellular membrane-bound organelle; cytoplasm; nucleusMolecular Function: prostaglandin-endoperoxide synthase activity; peroxidase activity; dioxygenase activity; metal ion binding; heme bindingBiological Process: regulation of blood pressure; xenobiotic metabolic process; cyclooxygenase pathway; arachidonic acid metabolic process; lipid metabolic process; response to oxidative stress; prostaglandin biosynthetic process; inflammatory response; regulation of cell proliferation Research Articles on PTGS1 1. Impacts of COX-1 gene polymorphisms on vascular outcomes in patients with ischemic stroke and treated with aspirin TOP Precautions All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines. Disclaimer While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information. TOP Products associated with PTGS1 elisa kit Reference Product PubMed Publications ALOX5 elisa kit >107 publications with PTGS1 and ALOX5 PLA2G4A elisa kit >92 publications with PTGS1 and PLA2G4A PTGES elisa kit >14 publications with PTGS1 and PTGES PTGIS elisa kit >8 publications with PTGS1 and PTGIS ALOX12 elisa kit >6 publications with PTGS1 and ALOX12 PTGES2 elisa kit >5 publications with PTGS1 and PTGES2 PTGES3 elisa kit >4 publications with PTGS1 and PTGES3 TBXAS1 elisa kit >3 publications with PTGS1 and TBXAS1 PLA2G2A elisa kit >2 publications with PTGS1 and PLA2G2A Pathways associated with PTGS1 elisa kit Products by Pathway Pathway Diagram Arachidonic Acid Metabolism Pathway antibodies Arachidonic Acid Metabolism Pathway Diagram Arachidonic Acid Metabolism Pathway antibodies Arachidonic Acid Metabolism Pathway Diagram Arachidonic Acid Metabolism Pathway antibodies Arachidonic Acid Metabolism Pathway Diagram Biological Oxidations Pathway antibodies Biological Oxidations Pathway Diagram C20 Prostanoid Biosynthesis Pathway antibodies C20 Prostanoid Biosynthesis Pathway Diagram COX Reactions Pathway antibodies COX Reactions Pathway Diagram Eicosanoid Synthesis Pathway antibodies Eicosanoid Synthesis Pathway Diagram Metabolic Pathways antibodies Metabolic Pathways Diagram Metabolism Pathway antibodies Metabolism Pathway Diagram Metabolism Of Lipids And Lipoproteins Pathway antibodies Metabolism Of Lipids And Lipoproteins Pathway Diagram Diseases associated with PTGS1 elisa kit Disease Name Pubmed Publications Inflammation Antibodies >978 publications with PTGS1 and Inflammation Cardiovascular Diseases Antibodies >478 publications with PTGS1 and Cardiovascular Diseases Pain Antibodies >343 publications with PTGS1 and Pain Necrosis Antibodies >278 publications with PTGS1 and Necrosis Carcinoma Antibodies >273 publications with PTGS1 and Carcinoma Edema Antibodies >226 publications with PTGS1 and Edema Heart Diseases Antibodies >156 publications with PTGS1 and Heart Diseases Hypertension Antibodies >145 publications with PTGS1 and Hypertension Stomach Ulcer Antibodies >140 publications with PTGS1 and Stomach Ulcer Adenocarcinoma Antibodies >126 publications with PTGS1 and Adenocarcinoma Organs/Tissues associated with PTGS1 elisa kit Organ/Tissue Name Pubmed Publications Blood Antibodies >1250 publications with PTGS1 and Blood Vascular Antibodies >686 publications with PTGS1 and Vascular Brain Antibodies >373 publications with PTGS1 and Brain Stomach Antibodies >353 publications with PTGS1 and Stomach Muscle Antibodies >345 publications with PTGS1 and Muscle Kidney Antibodies >295 publications with PTGS1 and Kidney Heart Antibodies >251 publications with PTGS1 and Heart Intestine Antibodies >219 publications with PTGS1 and Intestine Lung Antibodies >213 publications with PTGS1 and Lung Liver Antibodies >193 publications with PTGS1 and Liver TOP © 2006-24 MyBioSource.com. 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