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PKCQ elisa kit :: Mouse Protein Kinase C Theta ELISA Kit

Scan QR to view Datasheet Catalog #    MBS012335 PKCQ elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Protein Kinase C Theta (PKCQ), ELISA Kit

 Also Known As   

Mouse Protein Kinase C Theta ELISA Kit

 Product Gene Name   

PKCQ elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 OMIM    600448
 3D Structure    ModBase 3D Structure for Q04759
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 Species Reactivity    Mouse
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PKCQ elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PKCQ purchase    MBS012335 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Protein Kinase C Theta (PKCQ) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PKCQ. The ELISA analytical biochemical technique of the MBS012335 kit is based on PKCQ antibody-PKCQ antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PKCQ antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PKCQ. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PKCQ. It may not necessarily be applicable to this product.
 NCBI GI #    5453976
 NCBI GeneID    5588
 NCBI Accession #    NP_006248.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_006257.4 [Other Products]
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 UniProt Primary Accession #    Q04759 [Other Products]
 UniProt Secondary Accession #    Q14DH6; Q3MJF1; Q64FY5; Q9H508; Q9H549; B4DF52 [Other Products]
 UniProt Related Accession #    Q04759 [Other Products]
 Molecular Weight    81,865 Da
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 NCBI Official Full Name    protein kinase C theta type isoform 1
 NCBI Official Synonym Full Names    protein kinase C, theta
 NCBI Official Symbol    PRKCQ [Similar Products]
 NCBI Official Synonym Symbols   
PRKCT; nPKC-theta
[Similar Products]
 NCBI Protein Information    protein kinase C theta type
 UniProt Protein Name    Protein kinase C theta type
 UniProt Synonym Protein Names   
nPKC-theta
 Protein Family    Protein kinase
 UniProt Gene Name    PRKCQ [Similar Products]
 UniProt Synonym Gene Names    PRKCT [Similar Products]
 UniProt Entry Name    KPCT_HUMAN
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 NCBI Summary for PKCQ    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PKCQ    PKCT: an AGC kinase of the PKC family. A novel PKC: Ca2+ independent but still regulated by PS, DAG and phorbol esters. Contains 2 zinc-dependent phorbol-ester and DAG binding domains. Expressed in skeletal muscle and hematopoietic cells. May play a role in T cell receptor signaling and insulin resistance. Required for TCR-induced NF-kappaB activation in mature T lymphocytes.

Protein type: EC 2.7.11.13; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); Protein kinase, AGC; AGC group; PKC family; Delta subfamily

Chromosomal Location of Human Ortholog: 10p15

Cellular Component: plasma membrane; immunological synapse; cytosol

Molecular Function: protein serine/threonine kinase activity; protein binding; protein kinase C activity; metal ion binding; ubiquitin-protein ligase activity; ATP binding

Biological Process: positive regulation of interleukin-17 production; axon guidance; platelet activation; phototransduction, visible light; apoptosis; positive regulation of interleukin-2 biosynthetic process; membrane protein ectodomain proteolysis; negative regulation of insulin receptor signaling pathway; protein ubiquitination; protein amino acid phosphorylation; T cell receptor signaling pathway; activation of NF-kappaB transcription factor; positive regulation of interleukin-4 production; rhodopsin mediated signaling; regulation of rhodopsin mediated signaling; regulation of transcription, DNA-dependent; innate immune response; positive regulation of T cell proliferation; regulation of cell growth; positive regulation of T cell activation; blood coagulation; inflammatory response; cell structure disassembly during apoptosis
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 Research Articles on PKCQ    1. The results show that PKC-theta; has important diagnostic significance in gastrointestinal stromal tumors.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PKCQ elisa kitPathways associated with PKCQ elisa kit
 Reference Product  PubMed Publications
 BCL10 elisa kit  >18 publications with PKCQ and BCL10
 VAV1 elisa kit  >18 publications with PKCQ and VAV1
 IKBKB elisa kit  >18 publications with PKCQ and IKBKB
 CARD11 elisa kit  >16 publications with PKCQ and CARD11
 CHUK elisa kit  >14 publications with PKCQ and CHUK
 CASP3 elisa kit  >7 publications with PKCQ and CASP3
 LCK elisa kit  >7 publications with PKCQ and LCK
 STK39 elisa kit  >2 publications with PKCQ and STK39
 LCP2 elisa kit  >1 publications with PKCQ and LCP2
 IKBKG elisa kit  >1 publications with PKCQ and IKBKG
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptotic Cleavage Of Cellular Proteins Pathway antibodies  Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
 Apoptotic Execution Phase Pathway antibodies  Apoptotic Execution Phase Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 B Cell Receptor Signaling Pathway antibodies  B Cell Receptor Signaling Pathway Diagram
 Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway antibodies  Calcineurin-regulated NFAT-dependent Transcription In Lymphocytes Pathway Diagram
 Calcium Regulation In The Cardiac Cell Pathway antibodies  Calcium Regulation In The Cardiac Cell Pathway Diagram
Diseases associated with PKCQ elisa kitOrgans/Tissues associated with PKCQ elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >50 publications with PKCQ and Neoplasms
 Inflammation Antibodies  >30 publications with PKCQ and Inflammation
 Insulin Resistance Antibodies  >26 publications with PKCQ and Insulin Resistance
 Disease Models, Animal Antibodies  >18 publications with PKCQ and Disease Models, Animal
 Necrosis Antibodies  >17 publications with PKCQ and Necrosis
 Arthritis, Rheumatoid Antibodies  >13 publications with PKCQ and Arthritis, Rheumatoid
 Cardiovascular Diseases Antibodies  >10 publications with PKCQ and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >6 publications with PKCQ and Neoplasms, Experimental
 Fatty Liver Antibodies  >5 publications with PKCQ and Fatty Liver
 Liver Diseases Antibodies  >3 publications with PKCQ and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >236 publications with PKCQ and Blood
 Muscle Antibodies  >48 publications with PKCQ and Muscle
 Liver Antibodies  >16 publications with PKCQ and Liver
 Spleen Antibodies  >13 publications with PKCQ and Spleen
 Lung Antibodies  >13 publications with PKCQ and Lung
 Thymus Antibodies  >12 publications with PKCQ and Thymus
 Brain Antibodies  >12 publications with PKCQ and Brain
 Heart Antibodies  >11 publications with PKCQ and Heart
 Bone Marrow Antibodies  >7 publications with PKCQ and Bone Marrow
 Kidney Antibodies  >6 publications with PKCQ and Kidney
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