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Prg4 elisa kit :: Mouse Proteoglycan 4 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2880817 Prg4 elisa kit
Unit / Price
48-Strip-Wells  /  $380 +1 FREE 8GB USB
96-Strip-Wells  /  $500 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,170 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,840 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Proteoglycan 4 (Prg4), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Proteoglycan 4 ELISA Kit

 Product Synonym Names    Proteoglycan 4; Lubricin; Megakaryocyte-stimulating factor; Superficial zone proteoglycan; Prg4; Msf; Szp
 Product Gene Name   

Prg4 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q9JM99
 Species Reactivity    Mouse
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 Assay Type    Sandwich
 Detection Range    1.56-100 ng/mL
 Sensitivity    0.78 ng/mL
 Intra-Assay CV    <=4.7%
 Inter-Assay CV    <=8.1%
 Recovery    82%
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Prg4 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Prg4 purchase    MBS2880817 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Proteoglycan 4 (Prg4) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.56-100 ng/mL in biological research samples containing Prg4, with an estimated sensitivity of 0.78 ng/mL. The ELISA analytical biochemical technique of the MBS2880817 kit is based on Prg4 antibody-Prg4 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Prg4 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Prg4. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for Prg4. It may not necessarily be applicable to this product.
 NCBI GI #    158711681
 NCBI GeneID    96875
 NCBI Accession #    NP_001103616.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001110146.1 [Other Products]
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 UniProt Primary Accession #    Q9JM99 [Other Products]
 UniProt Secondary Accession #    Q3UEL1; Q3V198 [Other Products]
 UniProt Related Accession #    Q9JM99 [Other Products]
 Molecular Weight    47,989 Da
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 NCBI Official Full Name    proteoglycan 4 isoform 2
 NCBI Official Synonym Full Names    proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
 NCBI Official Symbol    Prg4 [Similar Products]
 NCBI Official Synonym Symbols   
MSF; SZP; CACP; JCAP; DOL54; lubricin
[Similar Products]
 NCBI Protein Information    proteoglycan 4
 UniProt Protein Name    Proteoglycan 4
 UniProt Synonym Protein Names   
Lubricin; Megakaryocyte-stimulating factor; Superficial zone proteoglycan
 Protein Family    Proteoglycan
 UniProt Gene Name    Prg4 [Similar Products]
 UniProt Synonym Gene Names    Msf; Szp [Similar Products]
 UniProt Entry Name    PRG4_MOUSE
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 UniProt Comments for Prg4    PRG4: Plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface. Defects in PRG4 are the cause of camptodactyly- arthropathy-coxa vara-pericarditis syndrome (CACP); also known as Jacobs syndrome. CACP is an autosomal recessive disorder. Individuals with CACP have normal appearing joints at birth but with advancing age develop joint failure associated with noninflammatory synoviocyte hyperplasia and subintimal fibrosis of the synovial capsule. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular region; extracellular space

Molecular Function: polysaccharide binding; scavenger receptor activity

Biological Process: immune response; negative regulation of interleukin-6 biosynthetic process; regulation of cell proliferation
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 Research Articles on Prg4    1. PRG4 is a novel putative ligand for CD44 and may control synoviocyte overgrowth in inflammatory arthropathies via a CD44-mediated mechanism.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Prg4 elisa kitDiseases associated with Prg4 elisa kit
 Reference Product  PubMed Publications
 Tgfb1 elisa kit  >15 publications with Prg4 and Tgfb1
 Col2a1 elisa kit  >5 publications with Prg4 and Col2a1
 Disease Name  Pubmed Publications
 Pericarditis Antibodies  >14 publications with Prg4 and Pericarditis
 Inflammation Antibodies  >8 publications with Prg4 and Inflammation
 Necrosis Antibodies  >7 publications with Prg4 and Necrosis
 Jacobs syndrome Antibodies  >6 publications with Prg4 and Jacobs syndrome
 Disease Models, Animal Antibodies  >6 publications with Prg4 and Disease Models, Animal
 Hyperplasia Antibodies  >4 publications with Prg4 and Hyperplasia
 Contracture Antibodies  >3 publications with Prg4 and Contracture
 Hypertrophy Antibodies  >2 publications with Prg4 and Hypertrophy
 Nervous System Diseases Antibodies  >2 publications with Prg4 and Nervous System Diseases
 Kidney Diseases Antibodies  >1 publications with Prg4 and Kidney Diseases
Organs/Tissues associated with Prg4 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >41 publications with Prg4 and Bone
 Blood Antibodies  >18 publications with Prg4 and Blood
 Connective Tissue Antibodies  >18 publications with Prg4 and Connective Tissue
 Bone Marrow Antibodies  >8 publications with Prg4 and Bone Marrow
 Muscle Antibodies  >7 publications with Prg4 and Muscle
 Eye Antibodies  >5 publications with Prg4 and Eye
 Embryonic Tissue Antibodies  >5 publications with Prg4 and Embryonic Tissue
 Lung Antibodies  >4 publications with Prg4 and Lung
 Kidney Antibodies  >4 publications with Prg4 and Kidney
 Liver Antibodies  >4 publications with Prg4 and Liver
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