NP_003010.4
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
37,728 Da
NCBI Official Full Name
pulmonary surfactant-associated protein D
NCBI Official Synonym Full Names
surfactant protein D
NCBI Protein Information
pulmonary surfactant-associated protein D; collectin 7; collectin-7; lung surfactant protein D; pulmonary surfactant apoprotein; surfactant, pulmonary-associated protein D; surfactant-associated protein, pulmonary 4
UniProt Protein Name
Pulmonary surfactant-associated protein D
UniProt Synonym Protein Names
Collectin-7; Lung surfactant protein D
UniProt Synonym Gene Names
UniProt Entry Name
SFTPD_HUMAN
NCBI Summary for SPD
The protein encoded by this gene is part of the innate immune response, protecting the lungs against inhaled microorganisms and chemicals. The encoded protein may also be involved in surfactant metabolism. [provided by RefSeq, Jul 2015]
UniProt Comments for SPD
SFTPD: Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. Belongs to the SFTPD family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 10q22.2-q23.1
Cellular Component: proteinaceous extracellular matrix; extracellular space; collagen; endocytic vesicle; lysosome; extracellular region
Molecular Function: protein binding; carbohydrate binding
Biological Process: receptor-mediated endocytosis; negative regulation of T cell proliferation; positive regulation of phagocytosis; defense response to bacterium; negative regulation of interleukin-2 biosynthetic process; innate immune response; respiratory gaseous exchange; surfactant homeostasis; alveolus development; macrophage chemotaxis; regulation of cytokine production
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Products associated with SPD elisa kit
Pathways associated with SPD elisa kit
Diseases associated with SPD elisa kit
Organs/Tissues associated with SPD elisa kit
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