P35242.1
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
26,157 Da
NCBI Official Full Name
Pulmonary surfactant-associated protein A
NCBI Official Synonym Full Names
surfactant associated protein A1
NCBI Protein Information
pulmonary surfactant-associated protein A
UniProt Protein Name
Pulmonary surfactant-associated protein A
UniProt Synonym Gene Names
UniProt Entry Name
SFTPA_MOUSE
UniProt Comments for Sftpa1
SFTPA2: In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Defects in SFTPA2 are a cause of pulmonary fibrosis idiopathic (IPF). Pulmonary fibrosis is a lung disease characterized by shortness of breath, radiographically evident diffuse pulmonary infiltrates, and varying degrees of inflammation and fibrosis on biopsy. It results in acute lung injury with subsequent scarring and endstage lung disease. Belongs to the SFTPA family.
Protein type: Secreted; Secreted, signal peptide
Cellular Component: cytoplasmic vesicle; extracellular space; multivesicular body; rough endoplasmic reticulum
Biological Process: positive regulation of phagocytosis
Research Articles on Sftpa1
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Products associated with Sftpa1 elisa kit
Pathways associated with Sftpa1 elisa kit
Organs/Tissues associated with Sftpa1 elisa kit
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