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PDXK elisa kit :: Mouse Pyridoxal /Pyridoxine Vitamin B6 Kinase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS025473 PDXK elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Pyridoxal /Pyridoxine Vitamin B6 Kinase (PDXK), ELISA Kit

 Also Known As   

Mouse Pyridoxal /Pyridoxine Vitamin B6 Kinase ELISA Kit

 Product Gene Name   

PDXK elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 21; NC_000021.8 (45138978..45182188). Location: 21q22.3
 OMIM    179020
 3D Structure    ModBase 3D Structure for O00764
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 Species Reactivity    Mouse
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 Assay Type    Sandwich
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PDXK elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PDXK purchase    MBS025473 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Pyridoxal /Pyridoxine Vitamin B6 Kinase (PDXK) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PDXK. The ELISA analytical biochemical technique of the MBS025473 kit is based on PDXK antibody-PDXK antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PDXK antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PDXK. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PDXK. It may not necessarily be applicable to this product.
 NCBI GI #    13543317
 NCBI GeneID    8566
 NCBI Accession #    AAH05825.1 [Other Products]
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 UniProt Primary Accession #    O00764 [Other Products]
 UniProt Secondary Accession #    Q7Z2Y0; Q9BS02 [Other Products]
 UniProt Related Accession #    O00764 [Other Products]
 Molecular Weight    35,102 Da
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 NCBI Official Full Name    PDXK protein
 NCBI Official Synonym Full Names    pyridoxal (pyridoxine, vitamin B6) kinase
 NCBI Official Symbol    PDXK [Similar Products]
 NCBI Official Synonym Symbols   
PKH; PNK; PRED79; C21orf97; C21orf124
[Similar Products]
 NCBI Protein Information    pyridoxal kinase; pyridoxine kinase; vitamin B6 kinase; pyridoxamine kinase
 UniProt Protein Name    Pyridoxal kinase
 UniProt Synonym Protein Names   
Pyridoxine kinase
 Protein Family    Pyridoxine kinase
 UniProt Gene Name    PDXK [Similar Products]
 UniProt Synonym Gene Names    C21orf124; C21orf97; PKH; PNK [Similar Products]
 UniProt Entry Name    PDXK_HUMAN
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 NCBI Summary for PDXK    The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
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 UniProt Comments for PDXK    PDXK: Required for synthesis of pyridoxal-5-phosphate from vitamin B6. Belongs to the pyridoxine kinase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.7.1.35; Kinase, other; Cofactor and Vitamin Metabolism - vitamin B6

Chromosomal Location of Human Ortholog: 21q22.3

Cellular Component: nucleoplasm; cytoplasm; cytosol; nucleus

Molecular Function: potassium ion binding; sodium ion binding; protein homodimerization activity; zinc ion binding; pyridoxal kinase activity; magnesium ion binding; lithium ion binding; ATP binding; pyridoxal phosphate binding

Biological Process: cell proliferation; vitamin metabolic process; vitamin B6 metabolic process; pyridoxal 5'-phosphate salvage; phosphorylation; water-soluble vitamin metabolic process; pyridoxal phosphate biosynthetic process
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 Research Articles on PDXK    1. The affected pyridoxine metabolism is discussed as an inborn genetic trait in epilepsy in general, rather than a specific sign of pyridoxine-dependent epilepsy solely.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with PDXK elisa kitPathways associated with PDXK elisa kit
 Reference Product  PubMed Publications
 PDXP elisa kit  >3 publications with PDXK and PDXP
 TRAPPC4 elisa kit  >1 publications with PDXK and TRAPPC4
 DBP elisa kit  >1 publications with PDXK and DBP
 TEF elisa kit  >1 publications with PDXK and TEF
 Products by Pathway  Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Vitamins And Cofactors Pathway antibodies  Metabolism Of Vitamins And Cofactors Pathway Diagram
 Metabolism Of Water-soluble Vitamins And Cofactors Pathway antibodies  Metabolism Of Water-soluble Vitamins And Cofactors Pathway Diagram
 Vitamin B6 Metabolism Pathway antibodies  Vitamin B6 Metabolism Pathway Diagram
 Vitamin B6 Metabolism Pathway antibodies  Vitamin B6 Metabolism Pathway Diagram
 Vitamins B6 Activation To Pyridoxal Phosphate Pathway antibodies  Vitamins B6 Activation To Pyridoxal Phosphate Pathway Diagram
 Pyridoxal 5'-phosphate Salvage Pathway antibodies  Pyridoxal 5'-phosphate Salvage Pathway Diagram
Diseases associated with PDXK elisa kitOrgans/Tissues associated with PDXK elisa kit
 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >5 publications with PDXK and Carcinoma
 Neoplasms Antibodies  >5 publications with PDXK and Neoplasms
 Drug Toxicity Antibodies  >2 publications with PDXK and Drug Toxicity
 Cardiovascular Diseases Antibodies  >1 publications with PDXK and Cardiovascular Diseases
 Neoplasms, Experimental Antibodies  >1 publications with PDXK and Neoplasms, Experimental
 Disease Models, Animal Antibodies  >1 publications with PDXK and Disease Models, Animal
 Inflammation Antibodies  >1 publications with PDXK and Inflammation
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >4 publications with PDXK and Lung
 Brain Antibodies  >3 publications with PDXK and Brain
 Liver Antibodies  >2 publications with PDXK and Liver
 Muscle Antibodies  >1 publications with PDXK and Muscle
 Blood Antibodies  >1 publications with PDXK and Blood
 Embryonic Tissue Antibodies  >1 publications with PDXK and Embryonic Tissue
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