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RORA elisa kit :: Mouse RAR-related orphan receptor A ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9321304 RORA elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

RAR-related orphan receptor A (RORA), ELISA Kit

 Also Known As   

Mouse Nuclear receptor ROR-alpha, RORA ELISA Kit

 Product Synonym Names    Mouse Nuclear receptor ROR-alpha (RORA) ELISA kit; DKFZp686M2414; MGC119326; MGC119329; NR1F1; ROR1; ROR2; ROR3; RZR-ALPHA; RZRA; RAR-related orphan receptor alpha; ROR-alpha; retinoic acid receptor-related orphan receptor alpha; retinoid-related orpha; RAR-related orphan receptor A
 Product Gene Name   

RORA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P51448
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of RORA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RORA purchase    MBS9321304 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the RAR-related orphan receptor A (RORA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RORA. The ELISA analytical biochemical technique of the MBS9321304 kit is based on RORA antibody-RORA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RORA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RORA. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for RORA. It may not necessarily be applicable to this product.
 NCBI GI #    583966108
 NCBI GeneID    19883
 NCBI Accession #    NP_001276845.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001289916.1 [Other Products]
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 UniProt Primary Accession #    P51448 [Other Products]
 UniProt Secondary Accession #    P70283; P97741; P97773; Q923G1 [Other Products]
 UniProt Related Accession #    P51448 [Other Products]
 Molecular Weight    58,845 Da
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 NCBI Official Full Name    nuclear receptor ROR-alpha isoform 2
 NCBI Official Synonym Full Names    RAR-related orphan receptor alpha
 NCBI Official Symbol    Rora [Similar Products]
 NCBI Official Synonym Symbols   
sg; ROR1; ROR2; ROR3; Nr1f1; nmf267; tmgc26; staggerer; 9530021D13Rik
[Similar Products]
 NCBI Protein Information    nuclear receptor ROR-alpha; nuclear receptor RZR-alpha; RAR-related orphan receptor A; retinoid-related orphan receptor-alpha; nuclear receptor subfamily 1 group F member 1
 UniProt Protein Name    Nuclear receptor ROR-alpha
 UniProt Synonym Protein Names   
Nuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; RAR-related orphan receptor A; Retinoid-related orphan receptor-alpha
 Protein Family    Nuclear receptor
 UniProt Gene Name    Rora [Similar Products]
 UniProt Synonym Gene Names    Nr1f1; Rzra [Similar Products]
 UniProt Entry Name    RORA_MOUSE
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 NCBI Summary for RORA    The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014]
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 UniProt Comments for RORA    RORA: Orphan nuclear receptor. Binds DNA as a monomer to hormone response elements (HRE) containing a single core motif half-site preceded by a short A-T-rich sequence. This isomer binds to the consensus sequence 5'-[AT][TA]A[AT][CGT]TAGGTCA-3'. Regulates a number of genes involved in lipid metabolism such as apolipoproteins AI, APOA5, CIII, CYP71 and PPARgamma, in cerebellum and photoreceptor development including PCP2, OPN1SW, OPN1SM AND ARR3, in circadian rhythm with BMAL1, and skeletal muscle development with MYOD1. Possible receptor for cholesterol or one of its derivatives. Monomer. Interacts (via the DNA-binding domain) with HIF1; the interaction enhances HIF1A transcription under hypoxia through increasing protein stability. By hypoxia and melatonin. Widely expressed in a number of tissues. Activated by CaMK4. Belongs to the nuclear hormone receptor family. NR1 subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor; DNA-binding

Cellular Component: nucleus

Molecular Function: protein binding; ligand-dependent nuclear receptor activity; DNA binding; zinc ion binding; sequence-specific DNA binding; metal ion binding; beta-catenin binding; steroid hormone receptor activity; oxysterol binding; transcription factor binding; transcription factor activity

Biological Process: granule cell precursor proliferation; intracellular receptor-mediated signaling pathway; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; regulation of macrophage activation; rhythmic process; positive regulation of circadian rhythm; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of fat cell differentiation; regulation of circadian rhythm; muscle cell differentiation; regulation of transcription, DNA-dependent; negative regulation of inflammatory response; xenobiotic metabolic process; regulation of steroid metabolic process; cerebellar Purkinje cell differentiation; positive regulation of transcription from RNA polymerase II promoter; steroid hormone mediated signaling; circadian regulation of gene expression; angiogenesis; nitric oxide biosynthetic process; cGMP metabolic process; regulation of smoothened signaling pathway
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 Research Articles on RORA    1. RORalpha is a transcriptional activator of insulin.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with RORA elisa kitDiseases associated with RORA elisa kit
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Circadian Clock Pathway antibodies  Circadian Clock Pathway Diagram
 Circadian Repression Of Expression By REV-ERBA Pathway antibodies  Circadian Repression Of Expression By REV-ERBA Pathway Diagram
 Circadian Rhythm - Mammal Pathway antibodies  Circadian Rhythm - Mammal Pathway Diagram
 Circadian Rhythm - Mammal Pathway antibodies  Circadian Rhythm - Mammal Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Generic Transcription Pathway antibodies  Generic Transcription Pathway Diagram
 Nuclear Receptor Transcription Pathway antibodies  Nuclear Receptor Transcription Pathway Diagram
 Nuclear Receptors Pathway antibodies  Nuclear Receptors Pathway Diagram
 RORA Activates Circadian Expression Pathway antibodies  RORA Activates Circadian Expression Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >23 publications with RORA and Neoplasms
 Inflammation Antibodies  >17 publications with RORA and Inflammation
 Ataxia Antibodies  >12 publications with RORA and Ataxia
 Nervous System Diseases Antibodies  >12 publications with RORA and Nervous System Diseases
 Skin Diseases Antibodies  >8 publications with RORA and Skin Diseases
 Carcinoma Antibodies  >8 publications with RORA and Carcinoma
 Brain Diseases Antibodies  >8 publications with RORA and Brain Diseases
 Liver Diseases Antibodies  >7 publications with RORA and Liver Diseases
 Breast Neoplasms Antibodies  >7 publications with RORA and Breast Neoplasms
 Necrosis Antibodies  >6 publications with RORA and Necrosis
Organs/Tissues associated with RORA elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >40 publications with RORA and Brain
 Bone Marrow Antibodies  >2 publications with RORA and Bone Marrow
 Ovary Antibodies  >2 publications with RORA and Ovary
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