NP_081625.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
99,552 Da
NCBI Official Full Name
RNA-binding protein 25
NCBI Official Synonym Full Names
RNA binding motif protein 25
NCBI Official Synonym Symbols
RNPC7; AI159652; AL023075; AU043498; 2600011C06Rik; 2610015J01Rik; A130095G20Rik [Similar Products]
NCBI Protein Information
RNA-binding protein 25; RNA-binding motif protein 25
UniProt Protein Name
RNA-binding protein 25
UniProt Synonym Protein Names
RNA-binding motif protein 25
UniProt Entry Name
RBM25_MOUSE
UniProt Comments for RBM25
RBM25: RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA splicing; RNA-binding; Spliceosome
Cellular Component: cytoplasm; nucleus
Molecular Function: nucleic acid binding; RNA binding; nucleotide binding
Biological Process: apoptosis; RNA splicing; mRNA processing
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Pathways associated with RBM25 elisa kit
Diseases associated with RBM25 elisa kit
Organs/Tissues associated with RBM25 elisa kit
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