NP_033095.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
25,169 Da
NCBI Official Full Name
GTP-binding protein Rit1 isoform 1
NCBI Official Synonym Full Names
Ras-like without CAAX 1
NCBI Protein Information
GTP-binding protein Rit1; ras-like without CAAX protein 1; RAS-like protein expressed in many tissues
UniProt Protein Name
GTP-binding protein Rit1
UniProt Synonym Protein Names
Ras-like protein expressed in many tissues; Ras-like without CAAX protein 1
UniProt Synonym Gene Names
UniProt Entry Name
RIT1_MOUSE
UniProt Comments for RIT1
RIT1: a small G protein of the Ras family. Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and p38-alpha signaling pathways and in NGF- dependent neuronal differentiation. Stimulation of the NGF and EGF receptor signaling pathways results in rapid and prolonged activation. Interacts with afadin, the C-terminal domain of RalGDS and RLF, but not with RIN1 and PIK3CA. RLF binds exclusively to the active GTP-bound form. Strongly interacts with BRAF, but only weakly with c-Raf. BRAF and c-RAF association is dependent upon the GTP-bound state. Interacts with RGL3. Shows rapid uncatalyzed guanine nucleotide dissociation rates, which are much faster than those of most Ras subfamily members.
Protein type: G protein, monomeric; G protein, monomeric, Ras; G protein
Cellular Component: membrane; plasma membrane; intracellular
Molecular Function: protein binding; GTP binding; nucleotide binding
Biological Process: small GTPase mediated signal transduction; Ras protein signal transduction; signal transduction
Research Articles on RIT1
Precautions
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Pathways associated with RIT1 elisa kit
Diseases associated with RIT1 elisa kit
Organs/Tissues associated with RIT1 elisa kit
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