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| Product Name
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SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 (SMARCC1), ELISA Kit
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| Also Known As
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Mouse SWI/SNF complex subunit SMARCC1, SMARCC1 ELISA Kit
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| Product Synonym Names
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Mouse SWI/SNF complex subunit SMARCC1 (SMARCC1) ELISA kit; BAF155; CRACC1; Rsc8; SRG3; SWI3; SWI/SNF complex 155 kDa subunit; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c1; chromatin remodeling complex BAF155 subunit; mammalian ch; SWI/SNF related; matrix associated; actin dependent regulator of chromatin; subfamily c; member 1
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| Product Gene Name
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[Similar Products]
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| Research Use Only
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For Research Use Only. Not for use in diagnostic procedures.
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| Request for Current Manual Insert
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| 3D Structure
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ModBase 3D Structure for P97496
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| Species Reactivity
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Mouse
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| Preparation and Storage
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Store all reagents at 2-8 degree C
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| Product Note
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Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
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| Other Notes
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Small volumes of SMARCC1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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| Searchable Terms for SMARCC1 purchase
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MBS9341506 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 (SMARCC1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SMARCC1. The ELISA analytical biochemical technique of the MBS9341506 kit is based on SMARCC1 antibody-SMARCC1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SMARCC1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SMARCC1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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| NCBI/Uniprot data below describe general gene information for SMARCC1. It may not necessarily be applicable to this product. |
| NCBI GI #
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112421097
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| NCBI GeneID
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20588
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| NCBI Accession #
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NP_033237.2
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[Other Products]
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| NCBI GenBank Nucleotide #
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NM_009211.2
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[Other Products]
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| UniProt Primary Accession #
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P97496
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[Other Products]
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| UniProt Secondary Accession #
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Q7TS80; Q7TT29
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[Other Products]
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| UniProt Related Accession #
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P97496
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[Other Products]
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| Molecular Weight
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122,890 Da
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| NCBI Official Full Name
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SWI/SNF complex subunit SMARCC1
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| NCBI Official Synonym Full Names
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SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
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| NCBI Official Symbol
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Smarcc1
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[Similar Products]
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| NCBI Official Synonym Symbols
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Rsc8; SRG3; BAF155; AI115498
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[Similar Products]
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| NCBI Protein Information
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SWI/SNF complex subunit SMARCC1; SWI3-related protein; BRG1-associated factor 155; SWI/SNF complex 155 kDa subunit; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1
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| UniProt Protein Name
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SWI/SNF complex subunit SMARCC1
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| UniProt Synonym Protein Names
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BRG1-associated factor 155; SWI/SNF complex 155 kDa subunit; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1; SWI3-related protein; BAF155
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| Protein Family
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SWI/SNF complex
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| UniProt Gene Name
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Smarcc1
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[Similar Products]
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| UniProt Synonym Gene Names
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Baf155; Srg3; BAF155
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[Similar Products]
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| UniProt Entry Name
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SMRC1_MOUSE
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| UniProt Comments for SMARCC1
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SMARCC1: a core component of the BAF (SWI/SNF) complex. This family of complexes remodels chromatin structures, enabling transcription factors to gain access to DNA. They play important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling is due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric structures, termed altosomes, each composed of 2 histones octamers. Belongs to the neural progenitors- specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain BAF53A and PHF10, are exchanged for homologous alternative BAF53B and BAF45B or BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand- bound VDR-mediated transrepression of the CYP27B1 gene. Component of 6 multiprotein chromatin-remodeling complexes: Swi/Snf-A (BAF), Swi/Snf-B (PBAF), Brm, Brg1(I), WINAC and Brg1(II). Each of the five complexes contains a catalytic subunit (either SMARCA4 or SMARCA2), and at least SMARCE1, BAF53A or BAF53B, SMARCC2 and SMARCB1. Other subunits specific to each of the complexes may also be present. Component of the BAF (hSWI/SNF) complex, which includes at least actin (ACTB), ARID1A, ARID1B, SMARCA2, SMARCA4, BAF53A, BAF53B, SMARCE1 SMARCC1, SMARCC2, SMARCB1, and one or more of SMARCD1, SMARCD2, or SMARCD3. In muscle cells, the BAF complex also contains DPF3. May also interact with the SIN3A histone deacetylase transcription repressor complex in conjunction with SMARCA2 and SMARCA4. The minimal complex composed of SMARCC1 and SMARCA4 seems to be able to associate with cyclin such as CCNE1 or transcription factors such as KLF1 or GATA1. Expressed in brain, heart, muscle, placenta, lung, liver, muscle, kidney and pancreas. Belongs to the SMARCC family.
Protein type: DNA-binding
Cellular Component: nucleoplasm; XY body; SWI/SNF complex; protein complex; nuclear chromatin; intracellular; nucleus
Molecular Function: protein binding; nucleosomal DNA binding; DNA binding; protein N-terminus binding; chromatin binding
Biological Process: nervous system development; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; chromatin modification; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; chromatin remodeling; organ morphogenesis; nucleosome disassembly; regulation of transcription, DNA-dependent; ATP-dependent chromatin remodeling; insulin receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; DNA packaging
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| Research Articles on SMARCC1
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1. we identify BAF155 as a substrate for arginine methyltransferase CARM1.
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| Precautions
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All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
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| Disclaimer
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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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| Pathways associated with SMARCC1 elisa kit | Diseases associated with SMARCC1 elisa kit |
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| Organs/Tissues associated with SMARCC1 elisa kit |
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ELISA Kit 
