Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow ATP2A1 rightarrow Mouse ATP2A1  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Zika virus envelope Recombinant Protein
 • 30S ribosomal protein S10 (rpsJ) Recombinant Protein
 • Serralysin B (prtB) Recombinant Protein
 • Toluene efflux pump membrane transporter TtgB (ttgB), partia... Recombinant Protein
 • FDX1 Antibody
 • spermatogenesis associated, serine-rich 1 (SPATS1) ELISA Kit
 • Stichodactyla Helianthus Neurotoxin [Gln9] Peptide
 • ARF6 Recombinant Protein
 • Granzymes B (Gzms-B) ELISA Kit
 • ADAM Metallopeptidase with Thrombospondin Type 1 Motif 4 (AD... ELISA Kit
 • Neurotensin receptor type 1 (NTSR1) Recombinant Protein
 • Intracellular sulfur oxidation protein DsrF (dsrF) Recombinant Protein
 • C-Myc-binding protein (MYCBP) ELISA Kit
 • A4GALT Antibody
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

ATP2A1 elisa kit :: Mouse Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (ATP2A1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS7215901 ATP2A1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (ATP2A1), ELISA Kit

 Also Known As   

Mouse Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (ATP2A1) ELISA Kit

 Product Gene Name   

ATP2A1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
 Request for Manual Insert    Request Manual
 OMIM    gene 601003
Section Bar
 Species Reactivity    Mouse
Section Bar
Section Bar
 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of ATP2A1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ATP2A1 purchase    MBS7215901 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (ATP2A1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ATP2A1. The ELISA analytical biochemical technique of the MBS7215901 kit is based on ATP2A1 antibody-ATP2A1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ATP2A1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ATP2A1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
 Product Categories/Family for ATP2A1 elisa kit    Signal Transduction
NCBI/Uniprot data below describe general gene information for ATP2A1. It may not necessarily be applicable to this product.
 NCBI GI #    10835220
 NCBI GeneID    487
 NCBI Accession #    NP_004311.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_004320.4 [Other Products]
Section Bar
 UniProt Secondary Accession #    O14984; A8K5J9; B3KY17 [Other Products]
 UniProt Related Accession #    O14983 [Other Products]
 Molecular Weight    95,199 Da
Table BarTOPTable Bar
 NCBI Official Full Name    sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform a
 NCBI Official Synonym Full Names    ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
 NCBI Official Symbol    ATP2A1 [Similar Products]
 NCBI Official Synonym Symbols   
ATP2A; SERCA1
[Similar Products]
 NCBI Protein Information    sarcoplasmic/endoplasmic reticulum calcium ATPase 1; calcium pump 1; SR Ca(2+)-ATPase 1; endoplasmic reticulum class 1/2 Ca(2+) ATPase; calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform
 UniProt Protein Name    Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
 UniProt Synonym Protein Names   
Calcium pump 1; Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform; Endoplasmic reticulum class 1/2 Ca(2+) ATPase
 Protein Family    Sarcoplasmic/endoplasmic reticulum calcium ATPase
 UniProt Gene Name    ATP2A1 [Similar Products]
 UniProt Synonym Gene Names    SERCA1; SR Ca(2+)-ATPase 1 [Similar Products]
 UniProt Entry Name    AT2A1_HUMAN
Section Bar
 NCBI Summary for ATP2A1    This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Oct 2013]
Section Bar
 UniProt Comments for ATP2A1    ATP2A1: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. Associated with sarcolipin (SLN) and phospholamban (PLN). Increased contractile activity leads to a decrease in SERCA1 expression, while decreased contractile activity leads to an increase in SERCA1 expression. Skeletal muscle, fast twitch muscle (type II) fibers. Reversibly inhibited by phospholamban (PLN) at low calcium concentrations. Dephosphorylated PLN decreases the apparent affinity of the ATPase for calcium. This inhibition is regulated by the phosphorylation of PLN. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter; Transporter, ion channel; Membrane protein, integral; Membrane protein, multi-pass; EC 3.6.3.8; Endoplasmic reticulum; Hydrolase

Chromosomal Location of Human Ortholog: 16p12.1

Cellular Component: I band; endoplasmic reticulum membrane; sarcoplasmic reticulum membrane; membrane; sarcoplasmic reticulum; perinuclear region of cytoplasm; integral to membrane; ER-Golgi intermediate compartment

Molecular Function: protein binding; protein homodimerization activity; calcium-transporting ATPase activity; calcium ion binding; ATP binding

Biological Process: apoptotic mitochondrial changes; positive regulation of fast-twitch skeletal muscle contraction; metabolic process; maintenance of mitochondrion localization; reduction of endoplasmic reticulum calcium ion concentration; calcium ion transport; elevation of endoplasmic reticulum calcium ion concentration; regulation of striated muscle contraction; blood coagulation; transmembrane transport; negative regulation of striated muscle contraction; elevation of mitochondrial calcium ion concentration

Disease: Brody Myopathy
Table BarTOPTable Bar
 Research Articles on ATP2A1    1. We performed a detailed study of SERCA1 protein expression in muscle of patients with BD and BS, and evaluated the alternative splicing of SERCA1 in primary cultures of normal human muscle
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with ATP2A1 elisa kitPathways associated with ATP2A1 elisa kit
 Reference Product  PubMed Publications
 SLN elisa kit  >3 publications with ATP2A1 and SLN
 PLN elisa kit  >3 publications with ATP2A1 and PLN
 CKM elisa kit  >2 publications with ATP2A1 and CKM
 TNNC2 elisa kit  >2 publications with ATP2A1 and TNNC2
 CACNA1S elisa kit  >1 publications with ATP2A1 and CACNA1S
 IRS1 elisa kit  >1 publications with ATP2A1 and IRS1
 Products by Pathway  Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimer's Disease Pathway antibodies  Alzheimer's Disease Pathway Diagram
 Alzheimers Disease Pathway antibodies  Alzheimers Disease Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Ion Channel Transport Pathway antibodies  Ion Channel Transport Pathway Diagram
 Ion Transport By P-type ATPases Pathway antibodies  Ion Transport By P-type ATPases Pathway Diagram
 Pancreatic Secretion Pathway antibodies  Pancreatic Secretion Pathway Diagram
 Pancreatic Secretion Pathway antibodies  Pancreatic Secretion Pathway Diagram
Diseases associated with ATP2A1 elisa kitOrgans/Tissues associated with ATP2A1 elisa kit
 Disease Name  Pubmed Publications
 Heart Failure Antibodies  >7 publications with ATP2A1 and Heart Failure
 Brody myopathy Antibodies  >4 publications with ATP2A1 and Brody myopathy
 Weight Loss Antibodies  >3 publications with ATP2A1 and Weight Loss
 Hypertrophy Antibodies  >3 publications with ATP2A1 and Hypertrophy
 Fibrosis Antibodies  >2 publications with ATP2A1 and Fibrosis
 Brain Diseases Antibodies  >2 publications with ATP2A1 and Brain Diseases
 Neoplasms, Experimental Antibodies  >1 publications with ATP2A1 and Neoplasms, Experimental
 Abnormalities, Drug-Induced Antibodies  >1 publications with ATP2A1 and Abnormalities, Drug-Induced
 Kidney Diseases Antibodies  >1 publications with ATP2A1 and Kidney Diseases
 Liver Diseases Antibodies  >1 publications with ATP2A1 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >103 publications with ATP2A1 and Muscle
 Heart Antibodies  >25 publications with ATP2A1 and Heart
 Nerve Antibodies  >8 publications with ATP2A1 and Nerve
 Brain Antibodies  >6 publications with ATP2A1 and Brain
 Embryonic Tissue Antibodies  >6 publications with ATP2A1 and Embryonic Tissue
 Lung Antibodies  >5 publications with ATP2A1 and Lung
 Thyroid Antibodies  >3 publications with ATP2A1 and Thyroid
 Prostate Antibodies  >2 publications with ATP2A1 and Prostate
 Eye Antibodies  >2 publications with ATP2A1 and Eye
 Liver Antibodies  >2 publications with ATP2A1 and Liver
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions