NP_036380.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47,305 Da
NCBI Official Full Name
selenide, water dikinase 2
NCBI Official Synonym Full Names
selenophosphate synthetase 2
NCBI Official Synonym Symbols
NCBI Protein Information
selenide, water dikinase 2; selenium donor protein 2; selenophosphate synthase 2
UniProt Protein Name
Selenide, water dikinase 2
UniProt Synonym Protein Names
Selenium donor protein 2; Selenophosphate synthase 2
UniProt Synonym Gene Names
UniProt Entry Name
SPS2_HUMAN
NCBI Summary for SEPHS2
This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. Genes encoding selenocysteine contain a stem-loop secondary structure in their 3' UTR called a selenocysteine insertion sequence (SECIS) element. The protein encoded by this gene contains a selenocysteine residue in its predicted active site. There is a pseudogene for this gene on chromosome 5. [provided by RefSeq, Aug 2013]
UniProt Comments for SEPHS2
SEPHS2: Synthesizes selenophosphate from selenide and ATP. Belongs to the selenophosphate synthase 1 family. Class I subfamily.
Protein type: Other Amino Acids Metabolism - selenoamino acid; EC 2.7.9.3; Kinase, other
Chromosomal Location of Human Ortholog: 16p11.2
Molecular Function: selenide, water dikinase activity; ATP binding
Biological Process: selenocysteine biosynthetic process; phosphorylation
Research Articles on SEPHS2
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Products associated with SEPHS2 elisa kit
Pathways associated with SEPHS2 elisa kit
Diseases associated with SEPHS2 elisa kit
Organs/Tissues associated with SEPHS2 elisa kit
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