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Sry elisa kit :: Mouse Sex-determining region Y protein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2884541 Sry elisa kit
Unit / Price
48-Strip-Wells  /  $420 +1 FREE 8GB USB
96-Strip-Wells  /  $560 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,445 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,520 +5 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Sex-determining region Y protein (Sry), ELISA Kit

 Also Known As   

Mouse Sex-determining region Y protein ELISA Kit

 Product Synonym Names    Sex-determining region Y protein; Testis-determining factor; Sry; Tdf; Tdy
 Product Gene Name   

Sry elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q05738
 Species Reactivity    Mouse
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 Preparation and Storage    For long term storage, please store the entire kit at -20 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Sry elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Sry purchase    MBS2884541 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Sex-determining region Y protein (Sry) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Sry. The ELISA analytical biochemical technique of the MBS2884541 kit is based on Sry antibody-Sry antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Sry antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Sry. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for Sry. It may not necessarily be applicable to this product.
 NCBI GI #    6755761
 NCBI GeneID    21674
 NCBI Accession #    NP_035694.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_011564.1 [Other Products]
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 UniProt Primary Accession #    Q05738 [Other Products]
 UniProt Related Accession #    Q05738 [Other Products]
 Molecular Weight    49,494 Da
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 NCBI Official Full Name    sex-determining region Y protein
 NCBI Official Synonym Full Names    sex determining region of Chr Y
 NCBI Official Symbol    Sry [Similar Products]
 NCBI Official Synonym Symbols   
Tdf; Tdy
[Similar Products]
 NCBI Protein Information    sex-determining region Y protein
 UniProt Protein Name    Sex-determining region Y protein
 UniProt Synonym Protein Names   
Testis-determining factor
 Protein Family    Sex-determining region Y protein
 UniProt Gene Name    Sry [Similar Products]
 UniProt Synonym Gene Names    Tdf; Tdy [Similar Products]
 UniProt Entry Name    SRY_MOUSE
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 UniProt Comments for Sry    SRY: Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. In male adult brain involved in the maintenance of motor functions of dopaminergic neurons. Involved in different aspects of gene regulation including promoter activation or repression. Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. Defects in SRY are the cause of 46,XY sex reversal type 1 (SRXY1). A condition characterized by male-to-female sex reversal in the presence of a normal 46,XY karyotype. Patients manifest rapid and early degeneration of their gonads, which are present in the adult as 'streak gonads', consisting mainly of fibrous tissue and variable amounts of ovarian stroma. As a result these patients do not develop secondary sexual characteristics at puberty. The external genitalia in these subjects are completely female, and Muellerian structures are normal. A 45,X chromosomal aberration involving SRY is found in Turner syndrome, a disease characterized by gonadal dysgenesis with short stature, streak gonads, variable abnormalities such as webbing of the neck, cubitus valgus, cardiac defects, low posterior hair line. The phenotype is female. Defects in SRY are the cause of 46,XX sex reversal type 1 (SRXX1). A condition in which male gonads develop in a genetic female (female to male sex reversal). Belongs to the SRY family.

Protein type: Nuclear receptor co-regulator; DNA-binding

Cellular Component: cytoplasm; nucleus

Molecular Function: calmodulin binding; DNA bending activity; DNA binding; protein binding; protein heterodimerization activity; transcription factor activity

Biological Process: cell differentiation; male gonad development; male sex determination; negative regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; sex determination; sex differentiation; transcription, DNA-dependent
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 Research Articles on Sry    1. Sry can be replaced by transgenic activation of its downstream target Sox9. This finding supports the existence of functional redundancy between the Y chromosome genes and their homologs encoded on other chromosomes.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with Sry elisa kitPathways associated with Sry elisa kit
 Reference Product  PubMed Publications
 Wt1 elisa kit  >100 publications with Sry and Wt1
 Amh elisa kit  >56 publications with Sry and Amh
 Nr0b1 elisa kit  >53 publications with Sry and Nr0b1
 Nr5a1 elisa kit  >36 publications with Sry and Nr5a1
 Uty elisa kit  >19 publications with Sry and Uty
 Zfpm2 elisa kit  >6 publications with Sry and Zfpm2
 Zfy1 elisa kit  >2 publications with Sry and Zfy1
 Etv2 elisa kit  >1 publications with Sry and Etv2
 Products by Pathway  Pathway Diagram
 Androgen Receptor Signaling Pathway antibodies  Androgen Receptor Signaling Pathway Diagram
 Deactivation Of The Beta-catenin Transactivating Complex Pathway antibodies  Deactivation Of The Beta-catenin Transactivating Complex Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Wnt Pathway antibodies  Signaling By Wnt Pathway Diagram
 TCF Dependent Signaling In Response To WNT Pathway antibodies  TCF Dependent Signaling In Response To WNT Pathway Diagram
Diseases associated with Sry elisa kit
 Disease Name  Pubmed Publications
 Gonadal Dysgenesis Antibodies  >403 publications with Sry and Gonadal Dysgenesis
 Heart Diseases Antibodies  >145 publications with Sry and Heart Diseases
 Heart Defects, Congenital Antibodies  >92 publications with Sry and Heart Defects, Congenital
 Nervous System Diseases Antibodies  >87 publications with Sry and Nervous System Diseases
 Disease Models, Animal Antibodies  >73 publications with Sry and Disease Models, Animal
 46,XY SEX REVERSAL 1 Antibodies  >41 publications with Sry and 46,XY SEX REVERSAL 1
 Oligospermia Antibodies  >38 publications with Sry and Oligospermia
 Kidney Diseases Antibodies  >37 publications with Sry and Kidney Diseases
 Liver Diseases Antibodies  >37 publications with Sry and Liver Diseases
 Hyperplasia Antibodies  >37 publications with Sry and Hyperplasia
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