Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow TNFRSF1B rightarrow Mouse TNFRSF1B  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Proteasome subunit beta type-9 (LMP2 - PSMB9) ELISA Kit
 • EWSR1 Antibody
 • Dulbecco's MEM Culture Media
 • U2AF1L4 Antibody
 • 6-Monoacetylmorphine (6-MAM) Antibody
 • Keratin Growth Factor (KGF) ELISA Kit
 • PLD2 (Phospho-Tyr169) Antibody
 • Phosphatidylserine (PS) ELISA Kit
 • KCNMA1 Antibody
 • SAE2 - UBA2 Antibody
 • Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody
 • Total Homocystein (HCY) ELISA Kit
 • ATG13 Antibody
 • calcium-calmodulin-dependen t protein kinase II beta (CAMK2B) ELISA Kit
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

TNFRSF1B elisa kit :: Mouse TNFRSF1B ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2500312
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $410 +1 FREE 8GB USB
96-Strip-Wells  /  $490 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,040 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,590 +4 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

TNFRSF1B, ELISA Kit

★Popular Item★
 Also Known As   

Mouse TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B) ELISA Kit

 Product Gene Name   

TNFRSF1B elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    191191
 3D Structure    ModBase 3D Structure for P20333
Section Bar
 Species Reactivity    Mouse
Section Bar
 Specificity    This assay has high sensitivity and excellent specificity for detection of Mouse TNFRSF1B. No significant cross-reactivity or interference between Mouse TNFRSF1B and analogues was observed. Note: Limited by current skills and knowledge, it is impossible for us to complete the cross- reactivity detection between Mouse TNFRSF1B and all the analogues, therefore, cross reaction may still exist.
Section Bar
 Samples    Serum, Plasma, Biological Fluids
 Assay Type    Sandwich
 Detection Range    7.813--500pg/mL
 Sensitivity    4.688pg/mL
Section Bar
 Preparation and Storage    Store at 4 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TNFRSF1B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TNFRSF1B purchase    MBS2500312 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the TNFRSF1B, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 7.813--500pg/mL in biological research samples containing TNFRSF1B, with an estimated sensitivity of 4.688pg/mL. The ELISA analytical biochemical technique of the MBS2500312 kit is based on TNFRSF1B antibody-TNFRSF1B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TNFRSF1B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TNFRSF1B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma, Biological Fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
 

Related Product Information for TNFRSF1B elisa kit

   Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of TNFRSF1B in Mouse serum, plasma and other biological fluids
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse TNFRSF1B. Standards or samples are added to the appropriate micro ELISA plate wells and bound by the specific antibody. Then a biotinylated detection antibody specific for Mouse TNFRSF1B and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse TNFRSF1B, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of Mouse TNFRSF1B. You can calculate the concentration of Mouse TNFRSF1B in the samples by comparing the OD of the samples to the standard curve.
Section Bar
 Typical Testing Data/Standard Curve (for reference only) of TNFRSF1B elisa kit    TNFRSF1B elisa kit Typical Testing Data/Standard Curve (for reference only) image
Table BarTOPTable Bar
Sample Manual Insert of MBS2500312. Click to request current manual
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for TNFRSF1B. It may not necessarily be applicable to this product.
 NCBI GI #    4507577
 NCBI GeneID    7133
 NCBI Accession #    NP_001057.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001066.2 [Other Products]
Section Bar
 UniProt Primary Accession #    P20333 [Other Products]
 UniProt Secondary Accession #    Q16042; Q6YI29; Q9UIH1; B1AJZ3 [Other Products]
 UniProt Related Accession #    P20333 [Other Products]
 Molecular Weight    28,461 Da
Table BarTOPTable Bar
 NCBI Official Full Name    tumor necrosis factor receptor superfamily member 1B
 NCBI Official Synonym Full Names    tumor necrosis factor receptor superfamily, member 1B
 NCBI Official Symbol    TNFRSF1B [Similar Products]
 NCBI Official Synonym Symbols   
p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II
[Similar Products]
 NCBI Protein Information    tumor necrosis factor receptor superfamily member 1B; TNF-R2; TNF-RII; p75 TNF receptor; p80 TNF-alpha receptor; soluble TNFR1B variant 1; tumor necrosis factor beta receptor; tumor necrosis factor binding protein 2; tumor necrosis factor receptor 2; tumor necrosis factor receptor type II
 UniProt Protein Name    Tumor necrosis factor receptor superfamily member 1B
 UniProt Synonym Protein Names   
Tumor necrosis factor receptor 2; TNF-R2; Tumor necrosis factor receptor type II; TNF-RII; TNFR-II; p75; p80 TNF-alpha receptor; CD_antigen: CD120b; INN: EtanerceptCleaved into the following 2 chains:Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2Alternative name(s):TBP-2; TBPII
 Protein Family    Tumor necrosis factor receptor superfamily
 UniProt Gene Name    TNFRSF1B [Similar Products]
 UniProt Synonym Gene Names    TNFBR; TNFR2; TNF-R2; TNF-RII; TNFR-II [Similar Products]
 UniProt Entry Name    TNR1B_HUMAN
Section Bar
 NCBI Summary for TNFRSF1B    The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]
Section Bar
 UniProt Comments for TNFRSF1B    TNF-R2: Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. Binds to TRAF2. Interacts with BMX. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, cytokine

Chromosomal Location of Human Ortholog: 1p36.22

Cellular Component: cell soma; perinuclear region of cytoplasm; integral to membrane; plasma membrane; extracellular region; nucleus; lipid raft

Molecular Function: protein binding; tumor necrosis factor receptor activity; ubiquitin protein ligase binding

Biological Process: DNA damage response, signal transduction resulting in induction of apoptosis; tumor necrosis factor-mediated signaling pathway; negative regulation of inflammatory response; immune response; RNA destabilization; inflammatory response; positive regulation of membrane protein ectodomain proteolysis; aging
Table BarTOPTable Bar
 Research Articles on TNFRSF1B    1. Inflammation mediated through TNFalpha and its receptors, TNFR1 and TNFR2, may represent an important component of a comorbidity-induced inflammatory response that partially drives the pathophysiology of heart failure (HF) with preserved ejection fraction.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with TNFRSF1B elisa kitPathways associated with TNFRSF1B elisa kit
 Reference Product  PubMed Publications
 TNF elisa kit  >99 publications with TNFRSF1B and TNF
 TRAF2 elisa kit  >4 publications with TNFRSF1B and TRAF2
 TRADD elisa kit  >3 publications with TNFRSF1B and TRADD
 TRAF1 elisa kit  >3 publications with TNFRSF1B and TRAF1
 BIRC3 elisa kit  >2 publications with TNFRSF1B and BIRC3
 BIRC2 elisa kit  >1 publications with TNFRSF1B and BIRC2
 Products by Pathway  Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Adipocytokine Signaling Pathway antibodies  Adipocytokine Signaling Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Amyotrophic Lateral Sclerosis (ALS) Pathway antibodies  Amyotrophic Lateral Sclerosis (ALS) Pathway Diagram
 Apoptosis Pathway antibodies  Apoptosis Pathway Diagram
 Apoptosis Modulation And Signaling Pathway antibodies  Apoptosis Modulation And Signaling Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 IL-3 Signaling Pathway antibodies  IL-3 Signaling Pathway Diagram
 Inflammatory Response Pathway antibodies  Inflammatory Response Pathway Diagram
Diseases associated with TNFRSF1B elisa kitOrgans/Tissues associated with TNFRSF1B elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >129 publications with TNFRSF1B and Necrosis
 Inflammation Antibodies  >37 publications with TNFRSF1B and Inflammation
 Cardiovascular Diseases Antibodies  >15 publications with TNFRSF1B and Cardiovascular Diseases
 Lung Diseases Antibodies  >12 publications with TNFRSF1B and Lung Diseases
 Heart Diseases Antibodies  >10 publications with TNFRSF1B and Heart Diseases
 Carcinoma Antibodies  >9 publications with TNFRSF1B and Carcinoma
 Obesity Antibodies  >9 publications with TNFRSF1B and Obesity
 Nervous System Diseases Antibodies  >8 publications with TNFRSF1B and Nervous System Diseases
 Hypertension Antibodies  >8 publications with TNFRSF1B and Hypertension
 Kidney Diseases Antibodies  >5 publications with TNFRSF1B and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >66 publications with TNFRSF1B and Blood
 Bone Antibodies  >14 publications with TNFRSF1B and Bone
 Heart Antibodies  >12 publications with TNFRSF1B and Heart
 Lung Antibodies  >9 publications with TNFRSF1B and Lung
 Kidney Antibodies  >8 publications with TNFRSF1B and Kidney
 Muscle Antibodies  >7 publications with TNFRSF1B and Muscle
 Vascular Antibodies  >7 publications with TNFRSF1B and Vascular
 Skin Antibodies  >6 publications with TNFRSF1B and Skin
 Nerve Antibodies  >4 publications with TNFRSF1B and Nerve
 Connective Tissue Antibodies  >4 publications with TNFRSF1B and Connective Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions