NP_660115.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
21,560 Da
NCBI Official Full Name
TRAF-interacting protein with FHA domain-containing protein A
NCBI Official Synonym Full Names
TRAF-interacting protein with forkhead-associated domain
NCBI Official Synonym Symbols
NCBI Protein Information
TRAF-interacting protein with FHA domain-containing protein A; TRAF2-binding protein; Traf2 binding protein
UniProt Protein Name
TRAF-interacting protein with FHA domain-containing protein A
UniProt Synonym Protein Names
TRAF2-binding protein
UniProt Synonym Gene Names
UniProt Entry Name
TIFA_MOUSE
UniProt Comments for TIFA
TIFA: Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.
Cellular Component: intracellular
Molecular Function: protein binding
Biological Process: I-kappaB kinase/NF-kappaB cascade
Research Articles on TIFA
Precautions
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Disclaimer
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Pathways associated with TIFA elisa kit
Diseases associated with TIFA elisa kit
Organs/Tissues associated with TIFA elisa kit
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