Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource rightarrow ELISA Kit rightarrow TREM2 rightarrow Mouse TREM2  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • 40S ribosomal protein S3 (RpS3) Recombinant Protein
 • Glutathione S Transferase (pGEX) Antibody
 • Homovanillic Acid (HVA) ELISA Kit
 • CD45RA Antibody
 • 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (Abhd5) Recombinant Protein
 • Glucagon (Gcg) Antibody
 • Complement Component 3 (C3) ELISA Kit
 • MAP2K1-MAP2K2 Antibody
 • Soluble Intercellular Adhesion Molecule-1 (SICAM1) ELISA Kit
 • Clathrin heavy chain 1 (CLTC) ELISA Kit
 • MAP2K2 - MKK2 - MEK2 Antibody
 • Epstein-Barr virus capsid antigen (EB-VCA) antibody (IgG) ELISA Kit
 • Alkaline phosphatase, tissue-nonspecific isozyme (Alpl) Recombinant Protein
 • vascular endothelial growth factor (VEGF-165) Recombinant Protein
 downarrow more ...
separator
separator
DatasheetFull DatasheetPrinter Friendly DatasheetPrint This DatasheetAdd to Compare ListHave Questions? Ask UsRequest for a Quotation today

TREM2 elisa kit :: Mouse Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS453700
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $425 +1 FREE 8GB USB
96-Strip-Wells  /  $560 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,480 +3 FREE 8GB USB
10x96-Strip-Wells  /  $4,820 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Triggering Receptor Expressed On Myeloid Cells 2 (TREM2), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) ELISA Kit

 Product Synonym Names    Trem2a; Trem2b; Trem2c; Triggering receptor expressed on monocytes 2
 Product Gene Name   

TREM2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
Table BarTOPTable Bar
  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q99NH8
 Species Reactivity    Mouse
Section Bar
 Specificity    This assay has high sensitivity and excellent specificity for detection of TREM2. No significant cross-reactivity or interference between TREM2 and analogues was observed.
Section Bar
 Samples    Serum, plasma, tissue homogenates, cell lysates and other biological fluids.
 Assay Type    Sandwich
 Detection Range    78.125-5000pg/mL
 Sensitivity    23.8pg/mL
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): 3 samples with low, middle and high level TREM2 were tested 20 times on one plate, respectively. Intra-Assay: CV<10%
 Inter-assay Precision    Inter-assay Precision (Precision between assays): 3 samples with low, middle and high level TREM2 were tested on 3 different plates, 8 replicates in each plate. CV(%) = SD/meanX100. Inter-Assay: CV<12%
Section Bar
 Preparation and Storage    For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TREM2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TREM2 purchase    MBS453700 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Triggering Receptor Expressed On Myeloid Cells 2 (TREM2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 78.125-5000pg/mL in biological research samples containing TREM2, with an estimated sensitivity of 23.8pg/mL. The ELISA analytical biochemical technique of the MBS453700 kit is based on TREM2 antibody-TREM2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TREM2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TREM2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell lysates and other biological fluids. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Table BarTOPTable Bar
 

Product Description specifically for TREM2 elisa kit

   Intended Uses: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of TREM2 in mouse serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to TREM2. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to TREM2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain TREM2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm +/- 10nm. The concentration of TREM2 in the samples is then determined by comparing the O.D. of the samples to the standard curve.
Section Bar
 Typical Testing Data/Standard Curve (for reference only) of TREM2 elisa kit    TREM2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
Table BarTOPTable Bar
Sample Manual Insert of MBS453700. Click to request current manual
Table BarTOPTable Bar
NCBI/Uniprot data below describe general gene information for TREM2. It may not necessarily be applicable to this product.
 NCBI GI #    440918700
 NCBI GeneID    83433
 NCBI Accession #    NP_001259007.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001272078.1 [Other Products]
Section Bar
 UniProt Primary Accession #    Q99NH8 [Other Products]
 UniProt Secondary Accession #    Q8CGK4; Q8CIA6; Q99NH9; Q9JL34 [Other Products]
 UniProt Related Accession #    Q99NH8 [Other Products]
 Molecular Weight    27,304 Da
Table BarTOPTable Bar
 NCBI Official Full Name    triggering receptor expressed on myeloid cells 2 isoform 2
 NCBI Official Synonym Full Names    triggering receptor expressed on myeloid cells 2
 NCBI Official Symbol    Trem2 [Similar Products]
 NCBI Official Synonym Symbols   
TREM-2; Trem2a; Trem2b; Trem2c
[Similar Products]
 NCBI Protein Information    triggering receptor expressed on myeloid cells 2
 UniProt Protein Name    Triggering receptor expressed on myeloid cells 2
 UniProt Synonym Protein Names   
Triggering receptor expressed on monocytes 2
 Protein Family    Triggering receptor expressed on myeloid cells
 UniProt Gene Name    Trem2 [Similar Products]
 UniProt Synonym Gene Names    Trem2a; Trem2b; Trem2c; TREM-2 [Similar Products]
Section Bar
 NCBI Summary for TREM2    The protein encoded by this gene is part of the immunoglobulin and lectin-like superfamily and functions as part of the innate immune system. This gene forms part of a cluster of genes on mouse chromosome 17 thought to be involved in innate immunity. This protein associates with the adaptor protein Dap-12 and recruits several factors, such as kinases and phospholipase C-gamma, to form a receptor signaling complex that activates myeloid cells, including dendritic cells and microglia. In humans homozygous loss-of-function mutations in this gene cause Nasu-Hakola disease and mutations in this gene may be risk factors to the development of Alzheimer's disease. In mouse mutations of this gene serve as a pathophysiological model for polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (Nasu-Hakola disease) and for inflammatory bowel disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jan 2013]
Section Bar
 UniProt Comments for TREM2    May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.
Table BarTOPTable Bar
 Research Articles on TREM2    1. TREM2 attenuates tau kinase activity through restriction of neuroinflammation, and thus protects against tau pathology.
Table BarTOPTable Bar
 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Table BarTOPTable Bar
Products associated with TREM2 elisa kitPathways associated with TREM2 elisa kit
 Reference Product  PubMed Publications
 Tyrobp elisa kit  >75 publications with TREM2 and Tyrobp
 Syk elisa kit  >8 publications with TREM2 and Syk
 Plxna1 elisa kit  >3 publications with TREM2 and Plxna1
 Sema6d elisa kit  >1 publications with TREM2 and Sema6d
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 DAP12 Interactions Pathway antibodies  DAP12 Interactions Pathway Diagram
 DAP12 Signaling Pathway antibodies  DAP12 Signaling Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Microglia Pathogen Phagocytosis Pathway antibodies  Microglia Pathogen Phagocytosis Pathway Diagram
 Osteoclast Differentiation Pathway antibodies  Osteoclast Differentiation Pathway Diagram
Diseases associated with TREM2 elisa kitOrgans/Tissues associated with TREM2 elisa kit
 Disease Name  Pubmed Publications
 Dementia Antibodies  >166 publications with TREM2 and Dementia
 Alzheimer Disease Antibodies  >152 publications with TREM2 and Alzheimer Disease
 Inflammation Antibodies  >84 publications with TREM2 and Inflammation
 Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy Antibodies  >35 publications with TREM2 and Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy
 Disease Models, Animal Antibodies  >34 publications with TREM2 and Disease Models, Animal
 Necrosis Antibodies  >19 publications with TREM2 and Necrosis
 Lung Diseases Antibodies  >15 publications with TREM2 and Lung Diseases
 Cognition Disorders Antibodies  >9 publications with TREM2 and Cognition Disorders
 Memory Disorders Antibodies  >8 publications with TREM2 and Memory Disorders
 Cardiovascular Diseases Antibodies  >7 publications with TREM2 and Cardiovascular Diseases
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >151 publications with TREM2 and Brain
 Blood Antibodies  >53 publications with TREM2 and Blood
 Lung Antibodies  >18 publications with TREM2 and Lung
 Bone Marrow Antibodies  >14 publications with TREM2 and Bone Marrow
 Spinal Cord Antibodies  >10 publications with TREM2 and Spinal Cord
 Joint Antibodies  >5 publications with TREM2 and Joint
 Mixed Antibodies  >3 publications with TREM2 and Mixed
 Skin Antibodies  >3 publications with TREM2 and Skin
 Embryonic Tissue Antibodies  >1 publications with TREM2 and Embryonic Tissue
Table BarTOPTable Bar
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions