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TYR elisa kit :: Mouse Tyrosinase ELISA Kit

Scan QR to view Datasheet Catalog #    MBS015936 TYR elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Tyrosinase, ELISA Kit

★Popular Item★
 Also Known As   

Mouse Tyrosinase ELISA Kit

 Product Gene Name   

TYR elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 Chromosome Location    Chromosome: 11; NC_000011.9 (88911040..89028927). Location: 11q14-q21
 OMIM    103470
 3D Structure    ModBase 3D Structure for P14679
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 Species Reactivity    Mouse
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Quantitative Sandwich
 Detection Range    62.5 pg/ml - 2000 pg/ml
 Sensitivity    10 pg/ml
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of TYR elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for TYR purchase    MBS015936 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Tyrosinase, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 62.5 pg/ml - 2000 pg/ml in biological research samples containing TYR, with an estimated sensitivity of 10 pg/ml. The ELISA analytical biochemical technique of the MBS015936 kit is based on TYR antibody-TYR antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TYR antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TYR. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for TYR elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of TYR (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS015936. Click to request current manual
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NCBI/Uniprot data below describe general gene information for TYR. It may not necessarily be applicable to this product.
 NCBI GI #    4507753
 NCBI GeneID    7299
 NCBI Accession #    NP_000363.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_000372.4 [Other Products]
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 UniProt Primary Accession #    P14679 [Other Products]
 UniProt Secondary Accession #    Q15675; Q15676; Q15680; Q8TAK4; Q9BYY0; Q9BZX1 [Other Products]
 UniProt Related Accession #    P14679 [Other Products]
 Molecular Weight    60,393 Da
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 NCBI Official Full Name    tyrosinase
 NCBI Official Synonym Full Names    tyrosinase
 NCBI Official Symbol    TYR [Similar Products]
 NCBI Official Synonym Symbols   
CMM8; OCA1A; OCAIA; SHEP3
[Similar Products]
 NCBI Protein Information    tyrosinase; LB24-AB; SK29-AB; monophenol monooxygenase; oculocutaneous albinism IA; tumor rejection antigen AB
 UniProt Protein Name    Tyrosinase
 UniProt Synonym Protein Names   
LB24-AB; Monophenol monooxygenase; SK29-AB; Tumor rejection antigen AB
 Protein Family    Tyrosinase
 UniProt Gene Name    TYR [Similar Products]
 UniProt Entry Name    TYRO_HUMAN
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 NCBI Summary for TYR    The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]
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 UniProt Comments for TYR    TYR: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone. Increased expression after UVB irradiation. Belongs to the tyrosinase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cofactor and Vitamin Metabolism - riboflavin; Membrane protein, integral; Amino Acid Metabolism - tyrosine; EC 1.14.18.1; Oxidoreductase

Chromosomal Location of Human Ortholog: 11q14.3

Cellular Component: perinuclear region of cytoplasm; lysosome; cytoplasm; melanosome membrane; integral to membrane; melanosome; Golgi-associated vesicle

Molecular Function: protein binding; protein homodimerization activity; copper ion binding; protein heterodimerization activity; monophenol monooxygenase activity

Biological Process: cell proliferation; visual perception; thymus development; melanin biosynthetic process from tyrosine; eye pigment biosynthetic process

Disease: Albinism, Ocular, With Sensorineural Deafness; Albinism, Oculocutaneous, Type Ib; Albinism, Oculocutaneous, Type Ia; Skin/hair/eye Pigmentation, Variation In, 3
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 Research Articles on TYR    1. A G47D & 1379delTT mutation was seen in 4 members of an oculocutaneous albinism family. An unrelated patient was a compound heterozygote for the G47D & D42N mutations.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with TYR elisa kitPathways associated with TYR elisa kit
 Reference Product  PubMed Publications
 TYRP1 elisa kit  >98 publications with TYR and TYRP1
 TAT elisa kit  >87 publications with TYR and TAT
 MLANA elisa kit  >15 publications with TYR and MLANA
 SILV elisa kit  >12 publications with TYR and SILV
 TPO elisa kit  >9 publications with TYR and TPO
 GOT1 elisa kit  >5 publications with TYR and GOT1
 DDC elisa kit  >5 publications with TYR and DDC
 Products by Pathway  Pathway Diagram
 (S)-reticuline Biosynthesis II Pathway antibodies  (S)-reticuline Biosynthesis II Pathway Diagram
 (S)-reticuline Biosynthesis II Pathway antibodies  (S)-reticuline Biosynthesis II Pathway Diagram
 Catecholamine Biosynthesis, Tyrosine => Dopamine => Noradrenaline => Adrenaline Pathway antibodies  Catecholamine Biosynthesis, Tyrosine => Dopamine => Noradrenaline => Adrenaline Pathway Diagram
 Catecholamine Biosynthesis, Tyrosine => Dopamine => Noradrenaline => Adrenaline Pathway antibodies  Catecholamine Biosynthesis, Tyrosine => Dopamine => Noradrenaline => Adrenaline Pathway Diagram
 L-dopachrome Biosynthesis Pathway antibodies  L-dopachrome Biosynthesis Pathway Diagram
 L-dopachrome Biosynthesis Pathway antibodies  L-dopachrome Biosynthesis Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Melanogenesis Pathway antibodies  Melanogenesis Pathway Diagram
 Riboflavin Metabolism Pathway antibodies  Riboflavin Metabolism Pathway Diagram
 Riboflavin Metabolism Pathway antibodies  Riboflavin Metabolism Pathway Diagram
Diseases associated with TYR elisa kitOrgans/Tissues associated with TYR elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >1880 publications with TYR and Neoplasms
 Nervous System Diseases Antibodies  >745 publications with TYR and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >389 publications with TYR and Cardiovascular Diseases
 Pain Antibodies  >379 publications with TYR and Pain
 Inflammation Antibodies  >335 publications with TYR and Inflammation
 Melanoma Antibodies  >313 publications with TYR and Melanoma
 Neoplasms, Experimental Antibodies  >265 publications with TYR and Neoplasms, Experimental
 Liver Diseases Antibodies  >201 publications with TYR and Liver Diseases
 Hypertension Antibodies  >190 publications with TYR and Hypertension
 Necrosis Antibodies  >187 publications with TYR and Necrosis
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >460 publications with TYR and Skin
 Eye Antibodies  >256 publications with TYR and Eye
 Thyroid Antibodies  >170 publications with TYR and Thyroid
 Connective Tissue Antibodies  >131 publications with TYR and Connective Tissue
 Mammary Gland Antibodies  >40 publications with TYR and Mammary Gland
 Ear Antibodies  >28 publications with TYR and Ear
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