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VEGF.C elisa kit :: Mouse Vascular Endothelial Growth Factor C ELISA Kit

Scan QR to view Datasheet Catalog #    MBS720611
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $455 +1 FREE 8GB USB
96-Strip-Wells  /  $660 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Vascular Endothelial Growth Factor C (VEGF.C), ELISA Kit

 Also Known As   

Mouse Vascular Endothelial Growth Factor C ELISA Kit

 Product Gene Name   

VEGF.C elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 OMIM    601528
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 Species Reactivity    Mouse
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 Samples    Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
 Assay Type    Competitive
 Detection Range    50-1000pg/mL
 Sensitivity    1.0pg/mL
 Intended Uses    This VEGF.C ELISA kit is a 1.5 hour solid-phase ELISA designed for the quantitative determination of mouse VEGF.C. This ELISA kit for research use only, not for therapeutic or diagnostic applications!
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of VEGF.C elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for VEGF.C purchase    MBS720611 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Vascular Endothelial Growth Factor C (VEGF.C) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 50-1000pg/mL in biological research samples containing VEGF.C, with an estimated sensitivity of 1.0pg/mL. The ELISA analytical biochemical technique of the MBS720611 kit is based on VEGF.C antibody-VEGF.C antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect VEGF.C antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, VEGF.C. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for VEGF.C elisa kit

   Principle of the Assay: VEGF.C ELISA kit applies the competitive enzyme immunoassay technique utilizing a monoclonal anti-VEGF.C antibody and an VEGF.C-HRP conjugate. The assay sample and buffer are incubated together with VEGF.C-HRP conjugate in pre-coated plate for one hour. After the incubation period, the wells are decanted and washed five times. The wells are then incubated with a substrate for HRP enzyme. The product of the enzyme-substrate reaction forms a blue colored complex. Finally, a stop solution is added to stop the reaction, which will then turn the solution yellow. The intensity of color is measured spectrophotometrically at 450nm in a microplate reader. The intensity of the color is inversely proportional to the VEGF.C concentration since VEGF.C from samples and VEGF.C-HRP conjugate compete for the anti-VEGF.C antibody binding site. Since the number of sites is limited, as more sites are occupied by VEGF.C from the sample, fewer sites are left to bind VEGF.C-HRP conjugate. A standard curve is plotted relating the intensity of the color (O.D.) to the concentration of standards. The VEGF.C concentration in each sample is interpolated from this standard curve.
 Product Categories/Family for VEGF.C elisa kit    Cancer
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 Typical Testing Data/Standard Curve (for reference only) of VEGF.C elisa kit    VEGF.C elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS720611. Click to request current manual
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NCBI/Uniprot data below describe general gene information for VEGF.C. It may not necessarily be applicable to this product.
 NCBI GI #    4885653
 NCBI GeneID    7424
 NCBI Accession #    NP_005420.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_005429.4 [Other Products]
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 UniProt Secondary Accession #    B2R9Q8 [Other Products]
 UniProt Related Accession #    P49767 [Other Products]
 Molecular Weight    46,883 Da
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 NCBI Official Full Name    vascular endothelial growth factor C preproprotein
 NCBI Official Synonym Full Names    vascular endothelial growth factor C
 NCBI Official Symbol    VEGFC [Similar Products]
 NCBI Official Synonym Symbols   
VRP; Flt4-L; LMPH1D
[Similar Products]
 NCBI Protein Information    vascular endothelial growth factor C; FLT4 ligand DHM; vascular endothelial growth factor-related protein
 UniProt Protein Name    Vascular endothelial growth factor C
 UniProt Synonym Protein Names   
Flt4 ligand; Flt4-L; Vascular endothelial growth factor-related protein; VRP
 Protein Family    Vascular endothelial growth factor
 UniProt Gene Name    VEGFC [Similar Products]
 UniProt Synonym Gene Names    VEGF-C; Flt4-L; VRP [Similar Products]
 UniProt Entry Name    VEGFC_HUMAN
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 NCBI Summary for VEGF.C    The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014]
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 UniProt Comments for VEGF.C    VEGFC: Growth factor active in angiogenesis, and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in angiogenesis of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. Homodimer; non-covalent and antiparallel. Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte. Belongs to the PDGF/VEGF growth factor family.

Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Cell cycle regulation; Cytokine; Secreted

Chromosomal Location of Human Ortholog: 4q34.3

Cellular Component: extracellular space; membrane; extracellular region

Molecular Function: protein binding; growth factor activity; vascular endothelial growth factor receptor 3 binding; chemoattractant activity

Biological Process: response to drug; substrate-bound cell migration; platelet activation; positive regulation of neuroblast proliferation; positive regulation of blood vessel endothelial cell migration; signal transduction; positive regulation of protein amino acid autophosphorylation; induction of positive chemotaxis; negative regulation of cell proliferation; positive regulation of angiogenesis; positive regulation of peptidyl-tyrosine phosphorylation; organ morphogenesis; platelet degranulation; morphogenesis of embryonic epithelium; positive chemotaxis; positive regulation of protein secretion; positive regulation of cell division; regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of cell proliferation; angiogenesis; negative regulation of blood pressure; positive regulation of cell-matrix adhesion; vascular endothelial growth factor receptor signaling pathway; blood coagulation; positive regulation of epithelial cell proliferation

Disease: Lymphedema, Hereditary, Id
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 Research Articles on VEGF.C    1. overexpression of lymphangiogenic factors VEGF-C and VEGF-D in colon adenocarcinoma was associated with increased vessel density in tumor-surrounding stroma.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with VEGF.C elisa kitPathways associated with VEGF.C elisa kit
 Reference Product  PubMed Publications
 LYVE1 elisa kit  >59 publications with VEGF.C and LYVE1
 FLT4 elisa kit  >36 publications with VEGF.C and FLT4
 PDPN elisa kit  >32 publications with VEGF.C and PDPN
 KDR elisa kit  >32 publications with VEGF.C and KDR
 EGFR elisa kit  >15 publications with VEGF.C and EGFR
 FLT1 elisa kit  >15 publications with VEGF.C and FLT1
 IGF1R elisa kit  >4 publications with VEGF.C and IGF1R
 SERPINE1 elisa kit  >3 publications with VEGF.C and SERPINE1
 FN1 elisa kit  >3 publications with VEGF.C and FN1
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Heart Development Pathway antibodies  Heart Development Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
Diseases associated with VEGF.C elisa kitOrgans/Tissues associated with VEGF.C elisa kit
 Disease Name  Pubmed Publications
 Neoplasm Metastasis Antibodies  >574 publications with VEGF.C and Neoplasm Metastasis
 Breast Neoplasms Antibodies  >147 publications with VEGF.C and Breast Neoplasms
 Lung Neoplasms Antibodies  >123 publications with VEGF.C and Lung Neoplasms
 Neoplasms, Experimental Antibodies  >117 publications with VEGF.C and Neoplasms, Experimental
 Inflammation Antibodies  >107 publications with VEGF.C and Inflammation
 Melanoma Antibodies  >61 publications with VEGF.C and Melanoma
 Cardiovascular Diseases Antibodies  >48 publications with VEGF.C and Cardiovascular Diseases
 Hyperplasia Antibodies  >45 publications with VEGF.C and Hyperplasia
 Skin Neoplasms Antibodies  >43 publications with VEGF.C and Skin Neoplasms
 Edema Antibodies  >43 publications with VEGF.C and Edema
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >1537 publications with VEGF.C and Vascular
 Lung Antibodies  >174 publications with VEGF.C and Lung
 Skin Antibodies  >122 publications with VEGF.C and Skin
 Embryonic Tissue Antibodies  >80 publications with VEGF.C and Embryonic Tissue
 Bone Antibodies  >79 publications with VEGF.C and Bone
 Bone Marrow Antibodies  >46 publications with VEGF.C and Bone Marrow
 Kidney Antibodies  >41 publications with VEGF.C and Kidney
 Placenta Antibodies  >39 publications with VEGF.C and Placenta
 Uterus Antibodies  >26 publications with VEGF.C and Uterus
 Brain Antibodies  >23 publications with VEGF.C and Brain
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