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VEGF-B elisa kit :: Mouse Vascular Endothelial cell Growth Factor B ELISA Kit

Scan QR to view Datasheet Catalog #    MBS726544
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $675 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,925 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,490 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

Vascular Endothelial cell Growth Factor B (VEGF-B), ELISA Kit

 Also Known As   

Mouse Vascular Endothelial cell Growth Factor B ELISA Kit

 Product Gene Name   

VEGF-B elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    Download PDF Manual View PDF Manual
 OMIM    601398
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 Species Reactivity    Mouse
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 Assay Type    Competitive
 Highest Standards    1000pg/mL
 Concentration of Standards    Concentration of Standards
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Sample Preparation    We suggest pre-experimenting with neat (undiluted) samples, 1:2 or 1:4 dilutions. Please avoid diluting your samples more than 1:10 as it would exceed the dilution limit set for this kit. If the expected concentration of the target is beyond the detection range of the kit, please contact our technical support team
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay.
 Other Notes    Small volumes of VEGF-B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for VEGF-B purchase    MBS726544 is a ready-to-use microwell, strip plate Competitive ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Vascular Endothelial cell Growth Factor B (VEGF-B) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing VEGF-B. The ELISA analytical biochemical technique of the MBS726544 kit is based on VEGF-B antibody-VEGF-B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect VEGF-B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, VEGF-B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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 Product Categories/Family for VEGF-B elisa kit    Cancer
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 Typical Testing Data/Standard Curve (for reference only) of VEGF-B elisa kit    VEGF-B elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS726544
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NCBI/Uniprot data below describe general gene information for VEGF-B. It may not necessarily be applicable to this product.
 NCBI GI #    4507887
 NCBI GeneID    7423
 NCBI Accession #    NP_003368.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_003377.4 [Other Products]
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 UniProt Secondary Accession #    Q16528 [Other Products]
 UniProt Related Accession #    P49765 [Other Products]
 Molecular Weight    21,261 Da
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 NCBI Official Full Name    vascular endothelial growth factor B isoform VEGFB-186
 NCBI Official Synonym Full Names    vascular endothelial growth factor B
 NCBI Official Symbol    VEGFB [Similar Products]
 NCBI Official Synonym Symbols   
VRF; VEGFL
[Similar Products]
 NCBI Protein Information    vascular endothelial growth factor B; VEGF-related factor
 UniProt Protein Name    Vascular endothelial growth factor B
 UniProt Synonym Protein Names   
VEGF-related factor; VRF
 UniProt Gene Name    VEGFB [Similar Products]
 UniProt Synonym Gene Names    VRF; VEGF-B; VRF [Similar Products]
 UniProt Entry Name    VEGFB_HUMAN
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 NCBI Summary for VEGF-B    This gene encodes a member of the PDGF (platelet-derived growth factor)/VEGF (vascular endothelial growth factor) family. The VEGF family members regulate the formation of blood vessels and are involved in endothelial cell physiology. This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1). Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Sep 2011]
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 UniProt Comments for VEGF-B    VEGFB: Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis. Homodimer; disulfide-linked. Can also form heterodimer with VEGF. Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. Belongs to the PDGF/VEGF growth factor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Secreted; Cell cycle regulation; Secreted, signal peptide; Cytokine

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: extracellular space; membrane; extracellular region

Molecular Function: heparin binding; protein binding; protein homodimerization activity; growth factor activity; protein heterodimerization activity; vascular endothelial growth factor receptor 1 binding; chemoattractant activity

Biological Process: response to drug; protein amino acid O-linked glycosylation; platelet activation; positive regulation of vascular endothelial growth factor receptor signaling pathway; positive regulation of vascular permeability; induction of positive chemotaxis; positive regulation of protein kinase B signaling cascade; positive regulation of peptidyl-tyrosine phosphorylation; platelet degranulation; positive chemotaxis; positive regulation of cell division; positive regulation of endothelial cell proliferation; angiogenesis; negative regulation of neuron apoptosis; vascular endothelial growth factor receptor signaling pathway; blood coagulation; cardiac muscle contraction; negative regulation of apoptosis
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 Research Articles on VEGF-B    1. VEGF-B has possible roles in cardiac protection, energy metabolism support, and neuroprotectin [review]
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with VEGF-B elisa kitPathways associated with VEGF-B elisa kit
 Reference Product  PubMed Publications
 FLT1 elisa kit  >10 publications with VEGF-B and FLT1
 KDR elisa kit  >6 publications with VEGF-B and KDR
 NRP1 elisa kit  >4 publications with VEGF-B and NRP1
 FLT4 elisa kit  >3 publications with VEGF-B and FLT4
 ERBB2 elisa kit  >1 publications with VEGF-B and ERBB2
 EGFR elisa kit  >1 publications with VEGF-B and EGFR
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Focal Adhesion Pathway antibodies  Focal Adhesion Pathway Diagram
 Heart Development Pathway antibodies  Heart Development Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 PI3K-Akt Signaling Pathway antibodies  PI3K-Akt Signaling Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
Diseases associated with VEGF-B elisa kitOrgans/Tissues associated with VEGF-B elisa kit
 Disease Name  Pubmed Publications
 Heart Diseases Antibodies  >11 publications with VEGF-B and Heart Diseases
 Nervous System Diseases Antibodies  >8 publications with VEGF-B and Nervous System Diseases
 Edema Antibodies  >7 publications with VEGF-B and Edema
 Hypertrophy Antibodies  >7 publications with VEGF-B and Hypertrophy
 Inflammation Antibodies  >6 publications with VEGF-B and Inflammation
 Liver Diseases Antibodies  >5 publications with VEGF-B and Liver Diseases
 Liver Neoplasms Antibodies  >5 publications with VEGF-B and Liver Neoplasms
 Neoplasm Metastasis Antibodies  >5 publications with VEGF-B and Neoplasm Metastasis
 Hypertension Antibodies  >5 publications with VEGF-B and Hypertension
 Myocardial Ischemia Antibodies  >5 publications with VEGF-B and Myocardial Ischemia
 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >92 publications with VEGF-B and Vascular
 Blood Antibodies  >38 publications with VEGF-B and Blood
 Heart Antibodies  >16 publications with VEGF-B and Heart
 Muscle Antibodies  >14 publications with VEGF-B and Muscle
 Brain Antibodies  >10 publications with VEGF-B and Brain
 Lung Antibodies  >8 publications with VEGF-B and Lung
 Placenta Antibodies  >7 publications with VEGF-B and Placenta
 Liver Antibodies  >7 publications with VEGF-B and Liver
 Eye Antibodies  >6 publications with VEGF-B and Eye
 Kidney Antibodies  >5 publications with VEGF-B and Kidney
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