NP_848913.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,901 Da
NCBI Official Full Name
Y+L amino acid transporter 2 isoform 1
NCBI Official Synonym Full Names
solute carrier family 7 (cationic amino acid transporter, y+ system), member 6
NCBI Protein Information
Y+L amino acid transporter 2
UniProt Protein Name
Y+L amino acid transporter 2
UniProt Synonym Protein Names
Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; Y+LAT2; y+LAT-2
UniProt Synonym Gene Names
UniProt Comments for SLC7A6
SLC7A6: Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells. Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 8|8 D3
Cellular Component: integral component of membrane; integral component of plasma membrane; intracellular membrane-bound organelle; membrane; plasma membrane
Molecular Function: amino acid transmembrane transporter activity; antiporter activity; L-amino acid transmembrane transporter activity
Biological Process: amino acid transport; transport
Research Articles on SLC7A6
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Products associated with SLC7A6 elisa kit
Pathways associated with SLC7A6 elisa kit
Diseases associated with SLC7A6 elisa kit
Organs/Tissues associated with SLC7A6 elisa kit
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