Q9Z2C8.1
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UniProt Primary Accession #
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UniProt Secondary Accession #
Molecular Weight
31,465 Da
NCBI Official Full Name
Y-box-binding protein 2
UniProt Protein Name
Y-box-binding protein 2
UniProt Synonym Protein Names
FRGY2 homolog; Germ cell-specific Y-box-binding protein
UniProt Synonym Gene Names
UniProt Comments for YBX2
YBX2: Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay.
Chromosomal Location of Human Ortholog: 11|11 B3
Cellular Component: cytoplasm; fibrillar center; intracellular ribonucleoprotein complex; nucleus; polysome
Molecular Function: chromatin binding; DNA binding; lipid binding; mRNA 3'-UTR binding; mRNA binding; nucleic acid binding; ribonucleoprotein complex binding; RNA binding; translation regulator activity
Biological Process: mRNA stabilization; negative regulation of binding; negative regulation of translation; oogenesis; regulation of transcription, DNA-templated; spermatid development
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Diseases associated with YBX2 elisa kit
Organs/Tissues associated with YBX2 elisa kit
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