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AIM2 elisa kit :: Mouse absent in melanoma 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9322550 AIM2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

absent in melanoma 2 (AIM2), ELISA Kit

 Also Known As   

Mouse Interferon-inducible protein AIM2, AIM2 ELISA Kit

 Product Synonym Names    Mouse Interferon-inducible protein AIM2 (AIM2) ELISA kit; PYHIN4; ; absent in melanoma 2
 Product Gene Name   

AIM2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q91VJ1
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of AIM2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for AIM2 purchase    MBS9322550 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the absent in melanoma 2 (AIM2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing AIM2. The ELISA analytical biochemical technique of the MBS9322550 kit is based on AIM2 antibody-AIM2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect AIM2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, AIM2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for AIM2. It may not necessarily be applicable to this product.
 NCBI GI #    162461985
 NCBI GeneID    383619
 NCBI Accession #    NP_001013801.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_001013779.2 [Other Products]
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 UniProt Primary Accession #    Q91VJ1 [Other Products]
 UniProt Related Accession #    Q91VJ1 [Other Products]
 Molecular Weight    40,155 Da
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 NCBI Official Full Name    interferon-inducible protein AIM2
 NCBI Official Synonym Full Names    absent in melanoma 2
 NCBI Official Symbol    Aim2 [Similar Products]
 NCBI Official Synonym Symbols   
Gm1313; Ifi210
[Similar Products]
 NCBI Protein Information    interferon-inducible protein AIM2; ifi-210; interferon-inducible protein 210; interferon-inducible protein p210
 UniProt Protein Name    Interferon-inducible protein AIM2
 UniProt Synonym Protein Names   
Interferon-inducible protein 210; Ifi-210; Interferon-inducible protein p210
 Protein Family    Protein
 UniProt Gene Name    Aim2 [Similar Products]
 UniProt Synonym Gene Names    Gm1313; Ifi210; Ifi-210 [Similar Products]
 UniProt Entry Name    AIM2_MOUSE
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 UniProt Comments for AIM2    AIM2: a tumor suppressor which may act by repressing NF-kappa-B transcriptional activity. Induced by interferon gamma. Defects in AIM2 may be a cause of microsatellite unstable colon cancers. AIM2 and various NOD-like receptors form multiprotein complexes called inflammasomes, which mediate caspase-1-dependent processing of pro-IL-1beta.

Protein type: Tumor suppressor

Cellular Component: cytoplasm; nucleus

Molecular Function: identical protein binding; protein binding; DNA binding; double-stranded DNA binding

Biological Process: apoptosis; immune system process; positive regulation of interleukin-1 beta secretion; activation of NF-kappaB transcription factor; positive regulation of protein oligomerization; positive regulation of interleukin-1 beta production; tumor necrosis factor-mediated signaling pathway; inhibition of NF-kappaB transcription factor; innate immune response; interleukin-1 beta secretion; inflammatory response; positive regulation of defense response to virus by host; activation of innate immune response
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 Research Articles on AIM2    1. The AIM2 inflammasome is a critical molecular platform for regulating IL-1beta release and survival during acute CNS S. aureus infection.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with AIM2 elisa kitDiseases associated with AIM2 elisa kit
 Products by Pathway  Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Cytosolic DNA-sensing Pathway antibodies  Cytosolic DNA-sensing Pathway Diagram
 Disease Name  Pubmed Publications
 Skin Diseases Antibodies  >10 publications with AIM2 and Skin Diseases
 Gastrointestinal Diseases Antibodies  >9 publications with AIM2 and Gastrointestinal Diseases
 Breast Neoplasms Antibodies  >4 publications with AIM2 and Breast Neoplasms
 Nervous System Diseases Antibodies  >1 publications with AIM2 and Nervous System Diseases
 Ovarian Neoplasms Antibodies  >1 publications with AIM2 and Ovarian Neoplasms
 Carcinoma, Squamous Cell Antibodies  >1 publications with AIM2 and Carcinoma, Squamous Cell
 Leukemia Antibodies  >1 publications with AIM2 and Leukemia
 Glioma Antibodies  >1 publications with AIM2 and Glioma
 Lymphoma Antibodies  >1 publications with AIM2 and Lymphoma
 Herpes Zoster Antibodies  >1 publications with AIM2 and Herpes Zoster
Organs/Tissues associated with AIM2 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Bone Marrow Antibodies  >9 publications with AIM2 and Bone Marrow
 Skin Antibodies  >6 publications with AIM2 and Skin
 Kidney Antibodies  >2 publications with AIM2 and Kidney
 Brain Antibodies  >2 publications with AIM2 and Brain
 Mixed Antibodies  >1 publications with AIM2 and Mixed
 Thymus Antibodies  >1 publications with AIM2 and Thymus
 Embryonic Tissue Antibodies  >1 publications with AIM2 and Embryonic Tissue
 Spleen Antibodies  >1 publications with AIM2 and Spleen
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