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ARG2 elisa kit :: Mouse arginase, type II ELISA Kit

Scan QR to view Datasheet Catalog #    MBS904661
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

arginase, type II (ARG2), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Arginase-2, mitochondrial, ARG2 ELISA Kit

 Product Synonym Names    Mouse Arginase-2; mitochondrial (ARG2) ELISA kit; L-arginine amidinohydrolase; L-arginine ureahydrolase; arginase 2; kidney arginase; nonhepatic arginase; arginase; type II
 Product Gene Name   

ARG2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS904661 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for O08691
 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of mouse ARG2. No significant cross-reactivity or interference between mouse ARG2 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Detection Range    0.156 ng/ml -10 ng/mL
 Sensitivity    <0.039 ng/mL
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ARG2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ARG2 purchase    MBS904661 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the arginase, type II (ARG2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.156 ng/ml -10 ng/mL in biological research samples containing ARG2, with an estimated sensitivity of <0.039 ng/mL. The ELISA analytical biochemical technique of the MBS904661 kit is based on ARG2 antibody-ARG2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ARG2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ARG2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for ARG2 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ARG2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ARG2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ARG2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ARG2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of ARG2 elisa kit    ARG2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS904661. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ARG2. It may not necessarily be applicable to this product.
 NCBI GI #    6753110
 NCBI GeneID    11847
 NCBI Accession #    NP_033835.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_009705.3 [Other Products]
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 UniProt Primary Accession #    O08691 [Other Products]
 UniProt Related Accession #    O08691 [Other Products]
 Molecular Weight    38,878 Da
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 NCBI Official Full Name    arginase-2, mitochondrial
 NCBI Official Synonym Full Names    arginase type II
 NCBI Official Symbol    Arg2 [Similar Products]
 NCBI Official Synonym Symbols   
AII; AU022422
[Similar Products]
 NCBI Protein Information    arginase-2, mitochondrial; type II arginase; kidney-type arginase; non-hepatic arginase
 UniProt Protein Name    Arginase-2, mitochondrial
 UniProt Synonym Protein Names   
Kidney-type arginase; Non-hepatic arginase; Type II arginase
 Protein Family    Arginase
 UniProt Gene Name    Arg2 [Similar Products]
 UniProt Entry Name    ARGI2_MOUSE
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 UniProt Comments for ARG2    ARG2: May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders. Belongs to the arginase family.

Protein type: Amino Acid Metabolism - arginine and proline; Hydrolase; Mitochondrial; EC 3.5.3.1

Cellular Component: mitochondrion

Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines; hydrolase activity; metal ion binding; arginase activity; nitric-oxide synthase binding

Biological Process: striated muscle contraction; negative regulation of nitric-oxide synthase activity; arginine metabolic process; arginine catabolic process to ornithine; negative regulation of striated muscle contraction; urea cycle
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 Research Articles on ARG2    1. HDAC2 is a critical regulator of Arg2 expression and thereby endothelial nitric oxide and endothelial function.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ARG2 elisa kitDiseases associated with ARG2 elisa kit
 Products by Pathway  Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Amoebiasis Pathway antibodies  Amoebiasis Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Arginine And Proline Metabolism Pathway antibodies  Arginine And Proline Metabolism Pathway Diagram
 Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway antibodies  Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway Diagram
 Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway antibodies  Polyamine Biosynthesis, Arginine => Ornithine => Putrescine Pathway Diagram
 Urea Cycle Pathway antibodies  Urea Cycle Pathway Diagram
 Urea Cycle Pathway antibodies  Urea Cycle Pathway Diagram
 Urea Cycle And Metabolism Of Amino Groups Pathway antibodies  Urea Cycle And Metabolism Of Amino Groups Pathway Diagram
 Arginine Degradation I (arginase Pathway) antibodies  Arginine Degradation I (arginase Pathway) Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >25 publications with ARG2 and Neoplasms
 Nervous System Diseases Antibodies  >17 publications with ARG2 and Nervous System Diseases
 Disease Models, Animal Antibodies  >16 publications with ARG2 and Disease Models, Animal
 Inflammation Antibodies  >12 publications with ARG2 and Inflammation
 Brain Diseases Antibodies  >12 publications with ARG2 and Brain Diseases
 Lung Diseases Antibodies  >11 publications with ARG2 and Lung Diseases
 Cardiovascular Diseases Antibodies  >10 publications with ARG2 and Cardiovascular Diseases
 Pain Antibodies  >10 publications with ARG2 and Pain
 Vascular Diseases Antibodies  >9 publications with ARG2 and Vascular Diseases
 Asthma Antibodies  >9 publications with ARG2 and Asthma
Organs/Tissues associated with ARG2 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >60 publications with ARG2 and Brain
 Kidney Antibodies  >27 publications with ARG2 and Kidney
 Intestine Antibodies  >20 publications with ARG2 and Intestine
 Thyroid Antibodies  >7 publications with ARG2 and Thyroid
 Pancreas Antibodies  >5 publications with ARG2 and Pancreas
 Prostate Antibodies  >5 publications with ARG2 and Prostate
 Eye Antibodies  >3 publications with ARG2 and Eye
 Thymus Antibodies  >3 publications with ARG2 and Thymus
 Embryonic Tissue Antibodies  >2 publications with ARG2 and Embryonic Tissue
 Ovary Antibodies  >1 publications with ARG2 and Ovary
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