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CIDEC elisa kit :: Mouse cell death-inducing DFFA-like effector c ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9337491 CIDEC elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

cell death-inducing DFFA-like effector c (CIDEC), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Cell death activator CIDE-3, CIDEC ELISA Kit

 Product Synonym Names    Mouse Cell death activator CIDE-3 (CIDEC) ELISA kit; CIDE-3; FLJ20871; Fsp27; cell death activator CIDE-3; fat specific protein 27; cell death-inducing DFFA-like effector c
 Product Gene Name   

CIDEC elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P56198
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CIDEC elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CIDEC purchase    MBS9337491 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cell death-inducing DFFA-like effector c (CIDEC) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CIDEC. The ELISA analytical biochemical technique of the MBS9337491 kit is based on CIDEC antibody-CIDEC antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CIDEC antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CIDEC. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for CIDEC. It may not necessarily be applicable to this product.
 NCBI GI #    30410022
 NCBI GeneID    14311
 NCBI Accession #    NP_848460.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_178373.3 [Other Products]
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 UniProt Primary Accession #    P56198 [Other Products]
 UniProt Secondary Accession #    Q499X5; Q8BNV7 [Other Products]
 UniProt Related Accession #    P56198 [Other Products]
 Molecular Weight    27,324 Da
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 NCBI Official Full Name    cell death activator CIDE-3
 NCBI Official Synonym Full Names    cell death-inducing DFFA-like effector c
 NCBI Official Symbol    Cidec [Similar Products]
 NCBI Official Synonym Symbols   
Fsp27; CIDE-3
[Similar Products]
 NCBI Protein Information    cell death activator CIDE-3; CIDE-3alpha; fat specific gene 27; fat-specific protein FSP27; cell death-inducing DFFA-like effector protein C
 UniProt Protein Name    Cell death activator CIDE-3
 UniProt Synonym Protein Names   
Cell death-inducing DFFA-like effector protein C; Fat-specific protein FSP27
 Protein Family    Cell death activator
 UniProt Gene Name    Cidec [Similar Products]
 UniProt Synonym Gene Names    Fsp27 [Similar Products]
 UniProt Entry Name    CIDEC_MOUSE
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 UniProt Comments for CIDEC    CIDEC: May act as a CEBPB coactivator in white adipose tissue to control the expression of a subset of CEBPB downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH. Binds to lipid droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear. In omental adipose tissue of obese patients matched for BMI, expression levels tend to correlate with insulin sensitivity. Expression is increased 2-3 fold in the group of patients with high insulin sensitivity, compared to the insulin- resistant group. This observation is consistent with the idea that triglyceride storage in adipocytes plays an important role in sequestering triglycerides and fatty acids away from the circulation and peripheral tissues, thus enhancing insulin sensitivity in liver and muscle. This effect is not significant in subcutaneous adipose tissue (PubMed:18509062). In subcutaneous adipose tissue of diabetic patients, tends to negatively correlate with body mass index and total fat mass, independently of insulin sensitivity (PubMed:18334488). 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis

Cellular Component: endoplasmic reticulum; lipid particle; intracellular; cytosol; nucleus

Biological Process: regulation of apoptosis; regulation of transcription, DNA-dependent; transcription, DNA-dependent; apoptosis
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 Research Articles on CIDEC    1. results demonstrate a crucial role for FSP27-ATGL interactions in regulating lipolysis, triglyceride accumulation, and insulin signaling in human adipocytes
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with CIDEC elisa kitOrgans/Tissues associated with CIDEC elisa kit
 Disease Name  Pubmed Publications
 Obesity Antibodies  >15 publications with CIDEC and Obesity
 Insulin Resistance Antibodies  >10 publications with CIDEC and Insulin Resistance
 Liver Diseases Antibodies  >8 publications with CIDEC and Liver Diseases
 Fatty Liver Antibodies  >8 publications with CIDEC and Fatty Liver
 Hyperinsulinism Antibodies  >7 publications with CIDEC and Hyperinsulinism
 Inflammation Antibodies  >4 publications with CIDEC and Inflammation
 Glucose Intolerance Antibodies  >2 publications with CIDEC and Glucose Intolerance
 Necrosis Antibodies  >2 publications with CIDEC and Necrosis
 Diabetes Mellitus, Experimental Antibodies  >2 publications with CIDEC and Diabetes Mellitus, Experimental
 Neoplasms Antibodies  >2 publications with CIDEC and Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Adipose Tissue Antibodies  >17 publications with CIDEC and Adipose Tissue
 Other Antibodies  >6 publications with CIDEC and Other
 Kidney Antibodies  >2 publications with CIDEC and Kidney
 Thyroid Antibodies  >2 publications with CIDEC and Thyroid
 Intestine Antibodies  >2 publications with CIDEC and Intestine
 Spleen Antibodies  >1 publications with CIDEC and Spleen
 Stomach Antibodies  >1 publications with CIDEC and Stomach
 Embryonic Tissue Antibodies  >1 publications with CIDEC and Embryonic Tissue
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