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CHGB elisa kit :: Mouse chromogranin B (secretogranin 1) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS913309 CHGB elisa kit
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
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 Product Name   

chromogranin B (secretogranin 1) (CHGB), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Secretogranin-1, CHGB ELISA Kit

 Product Synonym Names    Mouse Secretogranin-1 (CHGB) ELISA kit; SCG1; chromogranin B; secretogranin B; chromogranin B (secretogranin 1)
 Product Gene Name   

CHGB elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P16014
 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of mouse CHGB. No significant cross-reactivity or interference between mouse CHGB and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates.
 Assay Type    Sandwich
 Detection Range    9.38 pg/ml -600 pg/ml.
 Sensitivity    Typically less than 2.34 pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CHGB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CHGB purchase    MBS913309 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the chromogranin B (secretogranin 1) (CHGB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 9.38 pg/ml -600 pg/ml in biological research samples containing CHGB, with an estimated sensitivity of Typically less than 2.34 pg/ml. The ELISA analytical biochemical technique of the MBS913309 kit is based on CHGB antibody-CHGB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CHGB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CHGB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CHGB elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for CHGB has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any CHGB present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CHGB is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CHGB bound in the initial step. The color development is stopped and the intensity of the color is measured.
Sample Manual Insert of MBS913309. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CHGB. It may not necessarily be applicable to this product.
 NCBI GI #    6680934
 NCBI GeneID    12653
 NCBI Accession #    NP_031720.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_007694.4 [Other Products]
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 UniProt Primary Accession #    P16014 [Other Products]
 UniProt Related Accession #    P16014 [Other Products]
 Molecular Weight    77,969 Da
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 NCBI Official Full Name    secretogranin-1
 NCBI Official Synonym Full Names    chromogranin B
 NCBI Official Symbol    Chgb [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    secretogranin-1; cgB; sgI; chromogranin-B; secretogranin I
 UniProt Protein Name    Secretogranin-1
 UniProt Synonym Protein Names   
Chromogranin-B; CgB; Secretogranin I; SgI
 Protein Family    Secretogranin
 UniProt Gene Name    Chgb [Similar Products]
 UniProt Synonym Gene Names    Scg-1; Scg1; CgB; SgI [Similar Products]
 UniProt Entry Name    SCG1_MOUSE
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 UniProt Comments for CHGB    CHGB: a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular region; secretory granule

Molecular Function: protein binding
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 Research Articles on CHGB    1. Chromogranin B contributes to a highly efficient system that directly mediates monoamine accumulation and exocytosis in large dense core secretory vesicles.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with CHGB elisa kitOrgans/Tissues associated with CHGB elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >28 publications with CHGB and Neoplasms
 Nervous System Diseases Antibodies  >14 publications with CHGB and Nervous System Diseases
 Brain Diseases Antibodies  >10 publications with CHGB and Brain Diseases
 Mental Disorders Antibodies  >8 publications with CHGB and Mental Disorders
 Schizophrenia Antibodies  >7 publications with CHGB and Schizophrenia
 Cardiovascular Diseases Antibodies  >5 publications with CHGB and Cardiovascular Diseases
 Hypertension Antibodies  >5 publications with CHGB and Hypertension
 Breast Neoplasms Antibodies  >2 publications with CHGB and Breast Neoplasms
 Thyroid Diseases Antibodies  >2 publications with CHGB and Thyroid Diseases
 Hyperplasia Antibodies  >2 publications with CHGB and Hyperplasia
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >16 publications with CHGB and Brain
 Adrenal Gland Antibodies  >15 publications with CHGB and Adrenal Gland
 Pancreas Antibodies  >11 publications with CHGB and Pancreas
 Pituitary Gland Antibodies  >8 publications with CHGB and Pituitary Gland
 Intestine Antibodies  >6 publications with CHGB and Intestine
 Spinal Cord Antibodies  >3 publications with CHGB and Spinal Cord
 Embryonic Tissue Antibodies  >3 publications with CHGB and Embryonic Tissue
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