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CYP2R1 elisa kit :: Mouse cytochrome P450, family 2, subfamily R, polypeptide 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9339482 CYP2R1 elisa kit
Unit / Price
48-Strip-Wells  /  $500 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,250 +4 FREE 8GB USB
10x96-Strip-Wells  /  $6,395 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

cytochrome P450, family 2, subfamily R, polypeptide 1 (CYP2R1), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Vitamin D 25-hydroxylase, CYP2R1 ELISA Kit

 Product Synonym Names    Mouse Vitamin D 25-hydroxylase (CYP2R1) ELISA kit; MGC4663; cytochrome P450; family 2; R1; vitamin D 25-hydroxylase; cytochrome P450; family 2; subfamily R; polypeptide 1
 Product Gene Name   

CYP2R1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS9339482 COA    COA PDF
 3D Structure    ModBase 3D Structure for Q6VVW9
 Species Reactivity    Mouse
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
 Assay Type    Sandwich
 Detection Range    0.625 ng/ml - 20 ng/ml.
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of CYP2R1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for CYP2R1 purchase    MBS9339482 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cytochrome P450, family 2, subfamily R, polypeptide 1 (CYP2R1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625 ng/ml - 20 ng/ml in biological research samples containing CYP2R1, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9339482 kit is based on CYP2R1 antibody-CYP2R1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CYP2R1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CYP2R1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for CYP2R1 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, NOT for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of CYP2R1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9339482. Click to request current manual
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NCBI/Uniprot data below describe general gene information for CYP2R1. It may not necessarily be applicable to this product.
 NCBI GI #    34330188
 NCBI GeneID    244209
 NCBI Accession #    NP_796356.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_177382.4 [Other Products]
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 UniProt Primary Accession #    Q6VVW9 [Other Products]
 UniProt Related Accession #    Q6VVW9 [Other Products]
 Molecular Weight    57,313 Da
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 NCBI Official Full Name    vitamin D 25-hydroxylase
 NCBI Official Synonym Full Names    cytochrome P450, family 2, subfamily r, polypeptide 1
 NCBI Official Symbol    Cyp2r1 [Similar Products]
 NCBI Protein Information    vitamin D 25-hydroxylase; cytochrome P450, 2r1
 UniProt Protein Name    Vitamin D 25-hydroxylase
 UniProt Synonym Protein Names   
Cytochrome P450 2R1
 Protein Family    Vitamin D 25-hydroxylase
 UniProt Gene Name    Cyp2r1 [Similar Products]
 UniProt Entry Name    CP2R1_MOUSE
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 UniProt Comments for CYP2R1    CYP2R1: Has a D-25-hydroxylase activity on both forms of vitamin D, vitamin D(2) and D(3). Defects in CYP2R1 are the cause of rickets vitamin D- dependent type 1B (VDDR1B); also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency. A disorder caused by a selective deficiency of the active form of vitamin D (1,25-dihydroxyvitamin D3) and resulting in defective bone mineralization and clinical features of rickets. The patients sera have low calcium concentrations, low phosphate concentrations, elevated alkaline phosphatase activityand low levels of 25-hydroxyvitamin D. Belongs to the cytochrome P450 family.

Protein type: Oxidoreductase; EC 1.14.13.15

Cellular Component: membrane; intracellular membrane-bound organelle; endoplasmic reticulum; cytoplasm

Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; cholestanetriol 26-monooxygenase activity; metal ion binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; heme binding; steroid hydroxylase activity; oxidoreductase activity; oxygen binding; monooxygenase activity; vitamin D3 25-hydroxylase activity

Biological Process: organic acid metabolic process; xenobiotic metabolic process; exogenous drug catabolic process; vitamin D metabolic process
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 Research Articles on CYP2R1    1. CYP2R1 is the major enzyme responsible for 25-hydroxylation of vitamin D.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with CYP2R1 elisa kitDiseases associated with CYP2R1 elisa kit
 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 Cholecalciferol Biosynthesis Pathway antibodies  Cholecalciferol Biosynthesis Pathway Diagram
 Cholecalciferol Biosynthesis Pathway antibodies  Cholecalciferol Biosynthesis Pathway Diagram
 Cytochrome P450 - Arranged By Substrate Type Pathway antibodies  Cytochrome P450 - Arranged By Substrate Type Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Metabolism Of Steroid Hormones And Vitamins A And D Pathway antibodies  Metabolism Of Steroid Hormones And Vitamins A And D Pathway Diagram
 Phase 1 - Functionalization Of Compounds Pathway antibodies  Phase 1 - Functionalization Of Compounds Pathway Diagram
 Steroid Biosynthesis Pathway antibodies  Steroid Biosynthesis Pathway Diagram
 Steroid Biosynthesis Pathway antibodies  Steroid Biosynthesis Pathway Diagram
 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >7 publications with CYP2R1 and Liver Diseases
 Kidney Diseases Antibodies  >5 publications with CYP2R1 and Kidney Diseases
 Fibrosis Antibodies  >3 publications with CYP2R1 and Fibrosis
 Drug Toxicity Antibodies  >2 publications with CYP2R1 and Drug Toxicity
 Nervous System Diseases Antibodies  >2 publications with CYP2R1 and Nervous System Diseases
 Hepatitis Antibodies  >2 publications with CYP2R1 and Hepatitis
 Obesity Antibodies  >1 publications with CYP2R1 and Obesity
 Kidney Neoplasms Antibodies  >1 publications with CYP2R1 and Kidney Neoplasms
 Insulin Resistance Antibodies  >1 publications with CYP2R1 and Insulin Resistance
 Liver Failure Antibodies  >1 publications with CYP2R1 and Liver Failure
Organs/Tissues associated with CYP2R1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >20 publications with CYP2R1 and Liver
 Bone Antibodies  >14 publications with CYP2R1 and Bone
 Testis Antibodies  >4 publications with CYP2R1 and Testis
 Embryonic Tissue Antibodies  >1 publications with CYP2R1 and Embryonic Tissue
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