NP_031883.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
43,542 Da
NCBI Official Full Name
desert hedgehog protein
NCBI Official Synonym Full Names
desert hedgehog
NCBI Official Synonym Symbols
NCBI Protein Information
desert hedgehog protein; HHG-3
UniProt Protein Name
Desert hedgehog protein
UniProt Synonym Protein Names
HHG-3Cleaved into the following 2 chains:Desert hedgehog protein N-product; Desert hedgehog protein C-product
UniProt Synonym Gene Names
UniProt Entry Name
DHH_MOUSE
UniProt Comments for DHH
DHH: Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development. Defects in DHH may be the cause of partial gonadal dysgenesis with minifascicular neuropathy 46,XY (PGD). PGD is characterized by the presence of a testis on one side and a streak or an absent gonad at the other, persistence of Muellerian duct structures, and a variable degree of genital ambiguity. Defects in DHH may be the cause of complete pure gonadal dysgenesis 46,XY type (GDXYM); also known as male- limited gonadal dysgenesis 46,XY. GDXYM is a type of hypogonadism in which no functional gonads are present to induce puberty in an externally female person whose karyotype is then found to be XY. The gonads are found to be non-functional streaks. Belongs to the hedgehog family.
Protein type: Secreted; Cell development/differentiation; Secreted, signal peptide
Cellular Component: membrane; plasma membrane; extracellular region
Molecular Function: peptidase activity; protein binding; zinc ion binding; hydrolase activity; metal ion binding; patched binding; calcium ion binding
Biological Process: intein-mediated protein splicing; Leydig cell differentiation; cell-cell signaling; multicellular organismal development; male sex determination; regulation of steroid biosynthetic process; cell communication; proteolysis; spermatid development
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Pathways associated with DHH elisa kit
Diseases associated with DHH elisa kit
Organs/Tissues associated with DHH elisa kit
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