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ERAP1 elisa kit :: Mouse endoplasmic reticulum aminopeptidase 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9338214 ERAP1 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

endoplasmic reticulum aminopeptidase 1 (ERAP1), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Endoplasmic reticulum aminopeptidase 1, ERAP1 ELISA Kit

 Product Synonym Names    Mouse Endoplasmic reticulum aminopeptidase 1 (ERAP1) ELISA kit; A-LAP; ALAP; APPILS; ARTS-1; ARTS1; ERAAP; ERAAP1; KIAA0525; PILS-AP; PILSAP; adipocyte-derived leucine aminopeptidase; aminopeptidase PILS; aminopeptidase regulator of TNFR1 shedding; puromycin-insens; endoplasmic reticulum aminopeptidase 1
 Product Gene Name   

ERAP1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q9EQH2
 Species Reactivity    Mouse
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples.
 Assay Type    Sandwich (Quantitative)
 Detection Range    0.625 ng/ml - 20 ng/ml.
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of ERAP1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for ERAP1 purchase    MBS9338214 is a ready-to-use microwell, strip plate Sandwich (Quantitative) ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the endoplasmic reticulum aminopeptidase 1 (ERAP1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.625 ng/ml - 20 ng/ml in biological research samples containing ERAP1, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9338214 kit is based on ERAP1 antibody-ERAP1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ERAP1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ERAP1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for ERAP1 elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of ERAP1 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9338214. Click to request current manual
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NCBI/Uniprot data below describe general gene information for ERAP1. It may not necessarily be applicable to this product.
 NCBI GI #    13507656
 NCBI GeneID    80898
 NCBI Accession #    NP_109636.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_030711.4 [Other Products]
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 UniProt Primary Accession #    Q9EQH2 [Other Products]
 UniProt Secondary Accession #    Q6GTP5; Q9ET63 [Other Products]
 UniProt Related Accession #    Q9EQH2 [Other Products]
 Molecular Weight    106,599 Da
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 NCBI Official Full Name    endoplasmic reticulum aminopeptidase 1
 NCBI Official Synonym Full Names    endoplasmic reticulum aminopeptidase 1
 NCBI Official Symbol    Erap1 [Similar Products]
 NCBI Official Synonym Symbols   
[Similar Products]
 NCBI Protein Information    endoplasmic reticulum aminopeptidase 1; A-LAP; ARTS-1; PILS-AP; aminopeptidase PILS; VEGF-induced aminopeptidase; adipocyte-derived leucine aminopeptidase; puromycin-insensitive leucyl-specific aminopeptidase; type 1 tumor necrosis factor receptor shedding aminopeptidase regulator
 UniProt Protein Name    Endoplasmic reticulum aminopeptidase 1
 UniProt Synonym Protein Names   
ARTS-1; Adipocyte-derived leucine aminopeptidase; A-LAP; Aminopeptidase PILS; Puromycin-insensitive leucyl-specific aminopeptidase; PILS-AP; VEGF-induced aminopeptidase
 Protein Family    Endoplasmic reticulum aminopeptidase
 UniProt Gene Name    Erap1 [Similar Products]
 UniProt Synonym Gene Names    Appils; Arts1; A-LAP; PILS-AP [Similar Products]
 UniProt Entry Name    ERAP1_MOUSE
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 UniProt Comments for ERAP1    ARTS1: Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I- binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney. Belongs to the peptidase M1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Protease; EC 3.4.11.-

Cellular Component: extracellular space; intracellular membrane-bound organelle; membrane; endoplasmic reticulum lumen; endoplasmic reticulum; cytoplasm; extracellular region; integral to membrane

Molecular Function: peptidase activity; interleukin-6 receptor binding; metalloexopeptidase activity; metallopeptidase activity; hydrolase activity; zinc ion binding; metal ion binding; aminopeptidase activity; tumor necrosis factor receptor binding

Biological Process: positive regulation of angiogenesis; immune system process; membrane protein ectodomain proteolysis; proteolysis
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 Research Articles on ERAP1    1. These results suggest that secretion of ERAP1 is mediated by toll-like receptors via induction of intermediate cytokines
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with ERAP1 elisa kitDiseases associated with ERAP1 elisa kit
 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway antibodies  Antigen Presentation: Folding, Assembly And Peptide Loading Of Class I MHC Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Disease Name  Pubmed Publications
 Spondylitis, Ankylosing Antibodies  >39 publications with ERAP1 and Spondylitis, Ankylosing
 Psoriasis Antibodies  >16 publications with ERAP1 and Psoriasis
 Necrosis Antibodies  >12 publications with ERAP1 and Necrosis
 Skin Diseases Antibodies  >9 publications with ERAP1 and Skin Diseases
 Infection Antibodies  >6 publications with ERAP1 and Infection
 Inflammation Antibodies  >3 publications with ERAP1 and Inflammation
 Uterine Neoplasms Antibodies  >3 publications with ERAP1 and Uterine Neoplasms
 Intestinal Diseases Antibodies  >2 publications with ERAP1 and Intestinal Diseases
 Cell Transformation, Neoplastic Antibodies  >2 publications with ERAP1 and Cell Transformation, Neoplastic
 Adenocarcinoma Antibodies  >2 publications with ERAP1 and Adenocarcinoma
Organs/Tissues associated with ERAP1 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >4 publications with ERAP1 and Lung
 Heart Antibodies  >3 publications with ERAP1 and Heart
 Lymph Node Antibodies  >3 publications with ERAP1 and Lymph Node
 Skin Antibodies  >3 publications with ERAP1 and Skin
 Bone Antibodies  >2 publications with ERAP1 and Bone
 Liver Antibodies  >2 publications with ERAP1 and Liver
 Ovary Antibodies  >1 publications with ERAP1 and Ovary
 Spleen Antibodies  >1 publications with ERAP1 and Spleen
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