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FRZB elisa kit :: Mouse frizzled-related protein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS937358 FRZB elisa kit
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

frizzled-related protein (FRZB), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Secreted frizzled-related protein 3, FRZB ELISA Kit

 Product Synonym Names    Mouse Secreted frizzled-related protein 3 (FRZB) ELISA kit; FRE; FRITZ; FRP-3; FRZB-1; FRZB-PEN; FRZB1; FZRB; OS1; SFRP3; SRFP3; hFIZ; frizzled homolog-related; frizzled-related protein
 Product Gene Name   

FRZB elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P97401
 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Mouse FRZB. No significant cross-reactivity or interference between Mouse FRZB and analogues was observed.
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 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
 Protein Biological Process 1    Developmental Protein
 Protein Biological Process 3    Differentiation
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of FRZB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for FRZB purchase    MBS937358 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the frizzled-related protein (FRZB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing FRZB. The ELISA analytical biochemical technique of the MBS937358 kit is based on FRZB antibody-FRZB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect FRZB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, FRZB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for FRZB. It may not necessarily be applicable to this product.
 NCBI GI #    6755476
 NCBI GeneID    20378
 NCBI Accession #    NP_035486.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_011356.4 [Other Products]
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 UniProt Primary Accession #    P97401 [Other Products]
 UniProt Secondary Accession #    O09075; O09093; Q91W58 [Other Products]
 UniProt Related Accession #    P97401 [Other Products]
 Molecular Weight    36,011 Da
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 NCBI Official Full Name    secreted frizzled-related protein 3
 NCBI Official Synonym Full Names    frizzled-related protein
 NCBI Official Symbol    Frzb [Similar Products]
 NCBI Official Synonym Symbols   
Frp; Sfrp3; fritz; frzb-1; frezzled
[Similar Products]
 NCBI Protein Information    secreted frizzled-related protein 3; sFRP-3; frizzled-related protein 1; secreted frizzled-related sequence protein 3
 UniProt Protein Name    Secreted frizzled-related protein 3
 UniProt Synonym Protein Names   
Frezzled; Fritz; Frizzled-related protein 1; FrzB-1
 Protein Family    Frizzy aggregation protein
 UniProt Gene Name    Frzb [Similar Products]
 UniProt Synonym Gene Names    Fiz; Fre; Frzb1; Sfrp3; sFRP-3 [Similar Products]
 UniProt Entry Name    SFRP3_MOUSE
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 UniProt Comments for FRZB    FRZB: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development. Defects in FRZB are associated with susceptibility to osteoarthritis type 1(OS1). Osteoarthritis is a degenerative disease of the joints characterized by degradation of the hyaline articular cartilage and remodeling of the subchondral bone with sclerosis. Clinical symptoms include pain and joint stiffness often leading to significant disability and joint replacement. Belongs to the secreted frizzled-related protein (sFRP) family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function: Wnt-protein binding; protein binding

Biological Process: negative regulation of cell proliferation; inner ear morphogenesis; convergent extension involved in organogenesis; Wnt receptor signaling pathway; negative regulation of Wnt receptor signaling pathway; positive regulation of apoptosis; multicellular organismal development; positive regulation of fat cell differentiation; negative regulation of cell growth; cell differentiation
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 Research Articles on FRZB    1. left ventricles from post-MI mice showed an increased sFRP3 mRNA level, particularly in cardiac fibroblasts, and (iv) mechanical stretch enhanced sFRP3 expression and release in myocardial fibroblasts
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with FRZB elisa kitDiseases associated with FRZB elisa kit
 Products by Pathway  Pathway Diagram
 Adipogenesis Pathway antibodies  Adipogenesis Pathway Diagram
 Endochondral Ossification Pathway antibodies  Endochondral Ossification Pathway Diagram
 Disease Name  Pubmed Publications
 Osteoarthritis Antibodies  >38 publications with FRZB and Osteoarthritis
 Disease Models, Animal Antibodies  >10 publications with FRZB and Disease Models, Animal
 Breast Neoplasms Antibodies  >5 publications with FRZB and Breast Neoplasms
 Adenocarcinoma Antibodies  >5 publications with FRZB and Adenocarcinoma
 Kidney Neoplasms Antibodies  >4 publications with FRZB and Kidney Neoplasms
 Inflammation Antibodies  >4 publications with FRZB and Inflammation
 Kidney Diseases Antibodies  >4 publications with FRZB and Kidney Diseases
 Brain Diseases Antibodies  >4 publications with FRZB and Brain Diseases
 Neoplasm Metastasis Antibodies  >3 publications with FRZB and Neoplasm Metastasis
 Liver Neoplasms Antibodies  >3 publications with FRZB and Liver Neoplasms
Organs/Tissues associated with FRZB elisa kit
 Organ/Tissue Name  Pubmed Publications
 Embryonic Tissue Antibodies  >39 publications with FRZB and Embryonic Tissue
 Eye Antibodies  >12 publications with FRZB and Eye
 Brain Antibodies  >11 publications with FRZB and Brain
 Kidney Antibodies  >10 publications with FRZB and Kidney
 Lung Antibodies  >8 publications with FRZB and Lung
 Heart Antibodies  >6 publications with FRZB and Heart
 Stomach Antibodies  >6 publications with FRZB and Stomach
 Skin Antibodies  >4 publications with FRZB and Skin
 Inner Ear Antibodies  >4 publications with FRZB and Inner Ear
 Dorsal Root Ganglion Antibodies  >3 publications with FRZB and Dorsal Root Ganglion
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