NP_001171127.1
[Other Products]
NCBI GenBank Nucleotide #
|
[Other Products]
UniProt Primary Accession #
|
[Other Products]
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
105,481 Da
NCBI Official Full Name
glutamate receptor ionotropic, NMDA 1 isoform 2
NCBI Official Synonym Full Names
glutamate receptor, ionotropic, NMDA1 (zeta 1)
NCBI Official Synonym Symbols
NR1; GluN1; Nmdar; NMD-R1; NMDAR1; M100174; Rgsc174; GluRzeta1; GluRdelta1 [Similar Products]
NCBI Protein Information
glutamate receptor ionotropic, NMDA 1; glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1
UniProt Protein Name
Glutamate receptor ionotropic, NMDA 1
UniProt Synonym Protein Names
Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1
UniProt Synonym Gene Names
UniProt Entry Name
NMDZ1_MOUSE
UniProt Comments for GRIN1
NMDAR1: a subunit of N-methyl-D-aspartate (NMDA) receptors, members of the glutamate receptor channel superfamily. Possesses high calcium permeability and voltage-dependent sensitivity to magnesium and is modulated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. Mediates neuronal functions in glutamate neurotransmission. Three alternatively-spliced isoforms have been described.
Protein type: Channel, calcium; Channel, ligand-gated; Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: cell surface; cell; integral to plasma membrane; endoplasmic reticulum; dendrite; postsynaptic density; dendritic spine; integral to membrane; excitatory synapse; terminal button; N-methyl-D-aspartate selective glutamate receptor complex; postsynaptic membrane; synaptic vesicle; growth cone; membrane; cell soma; cytoplasm; plasma membrane; synapse; cell junction
Molecular Function: protein dimerization activity; voltage-gated cation channel activity; neurotransmitter binding; glutamate receptor binding; calcium channel activity; ion channel activity; receptor activity; calcium ion binding; calmodulin binding; protein binding; enzyme binding; extracellular-glutamate-gated ion channel activity; glutamate binding; ionotropic glutamate receptor activity; protein heterodimerization activity; glycine binding; N-methyl-D-aspartate selective glutamate receptor activity; cation channel activity; receptor binding
Biological Process: regulation of long-term neuronal synaptic plasticity; startle response; male mating behavior; prepulse inhibition; positive regulation of apoptosis; adult locomotory behavior; regulation of dendrite morphogenesis; rhythmic process; regulation of synaptic plasticity; response to morphine; sensory perception of pain; regulation of axonogenesis; calcium ion homeostasis; synaptic transmission; regulation of respiratory gaseous exchange; learning and/or memory; transport; calcium ion transport; conditioned taste aversion; regulation of neuron apoptosis; visual learning; negative regulation of neuron apoptosis; associative learning; cation transport; protein tetramerization; synaptic transmission, glutamatergic; neuromuscular process; response to amphetamine; learning; respiratory gaseous exchange; social behavior; pons maturation; memory; cellular calcium ion homeostasis; regulation of membrane potential; response to ethanol; suckling behavior; regulation of synaptogenesis; propylene metabolic process; long-term memory; olfactory learning; ionotropic glutamate receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; ion transport; cerebral cortex development; regulation of excitatory postsynaptic membrane potential; regulation of neuronal synaptic plasticity
Research Articles on GRIN1
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice. It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with GRIN1 elisa kit
Pathways associated with GRIN1 elisa kit
Diseases associated with GRIN1 elisa kit
Organs/Tissues associated with GRIN1 elisa kit
|