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HSP90AB1 elisa kit :: Mouse heat shock protein 90kDa alpha (cytosolic) , class B member 1 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS921345
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
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 Product Name   

heat shock protein 90kDa alpha (cytosolic) , class B member 1 (HSP90AB1), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Heat shock protein HSP 90-beta, HSP90AB1 ELISA Kit

 Product Synonym Names    Mouse Heat shock protein HSP 90-beta (HSP90AB1) ELISA kit; RP1-302G2.1; D6S182; FLJ26984; HSP90-BETA; HSP90B; HSPC2; HSPCB; OTTHUMP00000016518; OTTHUMP00000016519; heat shock 90kD protein 1; beta; heat shock 90kDa protein 1; beta; heat shock protein beta; heat shock protein 90kDa alpha (cytosolic); class B member 1
 Product Gene Name   

HSP90AB1 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS921345 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for P11499
 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of mouse HSP90AB1. No significant cross-reactivity or interference between mouse HSP90AB1 and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates, cell lysates
 Assay Type    Quantitative Sandwich
 Detection Range    15.6 pg/ml -1000 pg/ml
 Sensitivity    Typically less than 3.9 pg/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HSP90AB1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HSP90AB1 purchase    MBS921345 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the heat shock protein 90kDa alpha (cytosolic), class B member 1 (HSP90AB1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 15.6 pg/ml -1000 pg/ml in biological research samples containing HSP90AB1, with an estimated sensitivity of Typically less than 3.9 pg/ml. The ELISA analytical biochemical technique of the MBS921345 kit is based on HSP90AB1 antibody-HSP90AB1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HSP90AB1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HSP90AB1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates, cell lysates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for HSP90AB1 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for HSP90AB1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any HSP90AB1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for HSP90AB1 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of HSP90AB1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of HSP90AB1 elisa kit    HSP90AB1 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS921345. Click to request current manual
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NCBI/Uniprot data below describe general gene information for HSP90AB1. It may not necessarily be applicable to this product.
 NCBI GI #    40556608
 NCBI GeneID    15516
 NCBI Accession #    NP_032328.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_008302.3 [Other Products]
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 UniProt Primary Accession #    P11499 [Other Products]
 UniProt Secondary Accession #    O89078; Q3UIQ7 [Other Products]
 UniProt Related Accession #    P11499 [Other Products]
 Molecular Weight    83,281 Da
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 NCBI Official Full Name    heat shock protein HSP 90-beta
 NCBI Official Synonym Full Names    heat shock protein 90 alpha (cytosolic), class B member 1
 NCBI Official Symbol    Hsp90ab1 [Similar Products]
 NCBI Official Synonym Symbols   
90kDa; Hsp84; Hsp90; Hspcb; C81438; Hsp84-1; AL022974
[Similar Products]
 NCBI Protein Information    heat shock protein HSP 90-beta; TSTA; HSP 84; heat shock 84 kDa; heat shock protein 1, beta; heat shock protein, 84 kDa 1; heat shock 90kDa protein 1, beta; retinal degeneration slow protein; tumor-specific transplantation 84 kDa antigen; heat shock protein 90kDa alpha (cytosolic), class B member 1
 UniProt Protein Name    Heat shock protein HSP 90-beta
 UniProt Synonym Protein Names   
Heat shock 84 kDa; HSP 84; HSP84; Tumor-specific transplantation 84 kDa antigen; TSTA
 Protein Family    Heat shock protein
 UniProt Gene Name    Hsp90ab1 [Similar Products]
 UniProt Synonym Gene Names    Hsp84; Hsp84-1; Hspcb; HSP 84; HSP84; TSTA [Similar Products]
 UniProt Entry Name    HS90B_MOUSE
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 UniProt Comments for HSP90AB1    HSP90B: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Homodimer. Interacts with p53/TP53. Forms a complex with CDK6 and Hsp90/HSP90AB1. Interacts with UNC45A. Binding to UNC45A involves 2 UNC45A monomers per HSP90AB1 dimer. Interacts with CHORDC1 and DNAJC7. Interacts with FKBP4. Belongs to the heat shock protein 90 family.

Protein type: Heat shock protein; Chaperone

Cellular Component: signalosome; cell surface; mitochondrion; membrane; brush border membrane; basolateral plasma membrane; apical plasma membrane; cytoplasm; intracellular; inclusion body; cytosol

Molecular Function: protein binding; GTP binding; double-stranded RNA binding; unfolded protein binding; dATP binding; nucleotide binding; sulfonylurea receptor binding; protein kinase binding; kinase binding; ATP binding

Biological Process: positive regulation of protein binding; positive regulation of protein import into nucleus, translocation; protein folding; positive regulation of cell size; response to stress; negative regulation of neuron apoptosis; placenta development
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 Research Articles on HSP90AB1    1. Reveal an opposite role of Hsp70 and Hsp90 in regulating TGF-beta signaling by implicating CHIP-mediated Smad3 ubiquitination and degradation. This study provides a new insight into understanding the regulation of the TGF-beta signaling by chaperones.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HSP90AB1 elisa kitPathways associated with HSP90AB1 elisa kit
 Reference Product  PubMed Publications
 Akt1 elisa kit  >1 publications with HSP90AB1 and Akt1
 Products by Pathway  Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Axon Guidance Pathway antibodies  Axon Guidance Pathway Diagram
 Developmental Biology Pathway antibodies  Developmental Biology Pathway Diagram
 NOD-like Receptor Signaling Pathway antibodies  NOD-like Receptor Signaling Pathway Diagram
 NOD-like Receptor Signaling Pathway antibodies  NOD-like Receptor Signaling Pathway Diagram
 Pathways In Cancer antibodies  Pathways In Cancer Diagram
 Progesterone-mediated Oocyte Maturation Pathway antibodies  Progesterone-mediated Oocyte Maturation Pathway Diagram
 Progesterone-mediated Oocyte Maturation Pathway antibodies  Progesterone-mediated Oocyte Maturation Pathway Diagram
 Prostate Cancer Pathway antibodies  Prostate Cancer Pathway Diagram
Diseases associated with HSP90AB1 elisa kitOrgans/Tissues associated with HSP90AB1 elisa kit
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >15 publications with HSP90AB1 and Neoplasms
 Carcinoma Antibodies  >7 publications with HSP90AB1 and Carcinoma
 Gonadal Disorders Antibodies  >4 publications with HSP90AB1 and Gonadal Disorders
 Immune System Diseases Antibodies  >4 publications with HSP90AB1 and Immune System Diseases
 Inflammation Antibodies  >3 publications with HSP90AB1 and Inflammation
 Disease Models, Animal Antibodies  >3 publications with HSP90AB1 and Disease Models, Animal
 Liver Neoplasms Antibodies  >3 publications with HSP90AB1 and Liver Neoplasms
 Ovarian Neoplasms Antibodies  >3 publications with HSP90AB1 and Ovarian Neoplasms
 Adenocarcinoma Antibodies  >3 publications with HSP90AB1 and Adenocarcinoma
 Liver Diseases Antibodies  >3 publications with HSP90AB1 and Liver Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >5 publications with HSP90AB1 and Blood
 Brain Antibodies  >5 publications with HSP90AB1 and Brain
 Intestine Antibodies  >4 publications with HSP90AB1 and Intestine
 Ovary Antibodies  >4 publications with HSP90AB1 and Ovary
 Testis Antibodies  >3 publications with HSP90AB1 and Testis
 Liver Antibodies  >3 publications with HSP90AB1 and Liver
 Bone Marrow Antibodies  >3 publications with HSP90AB1 and Bone Marrow
 Kidney Antibodies  >3 publications with HSP90AB1 and Kidney
 Bone Antibodies  >3 publications with HSP90AB1 and Bone
 Embryonic Tissue Antibodies  >3 publications with HSP90AB1 and Embryonic Tissue
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