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HEXA elisa kit :: Mouse hexosaminidase A (alpha polypeptide) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS701489
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
48-Strip-Wells  /  $590 +1 FREE 8GB USB
96-Strip-Wells  /  $850 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,880 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,440 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

hexosaminidase A (alpha polypeptide) (HEXA), ELISA Kit

 Also Known As   

Mouse beta-hexosaminidase A, beta-Hex A ELISA Kit

 Product Synonym Names    Mouse beta-hexosaminidase A; beta-Hex A ELISA Kit; MGC99608; TSD; N-acetyl-beta-glucosaminidase; beta-N-acetylhexosaminidase; hexosaminidase A; hexosaminidase A (alpha polypeptide)
 Product Gene Name   

HEXA elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Manual Insert    PDF Manual
 MBS701489 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for P29416
 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Mouse HEXA. No significant cross-reactivity or interference between Mouse HEXA and analogues was observed.
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 Samples    Serum, plasma, tissue homogenates
 Assay Type    Sandwich
 Detection Range    3.12 uU/ml-200 uU/ml
 Sensitivity    0.78 uU/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Other Notes    Small volumes of HEXA elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HEXA purchase    MBS701489 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the hexosaminidase A (alpha polypeptide) (HEXA) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards render a theoretical kit detection range of 3.12 uU/ml-200 uU/ml in biological research samples containing HEXA, with an estimated sensitivity of 0.78 uU/ml. The ELISA analytical biochemical technique of the MBS701489 kit is based on HEXA antibody-HEXA antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HEXA antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HEXA. Appropriate sample types include undiluted human body fluids and/or tissue homogenates, secretions such as Serum, plasma, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for HEXA elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for beta-Hex A has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any beta-Hex A present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for beta-Hex A is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of beta-Hex A bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of HEXA elisa kit    HEXA elisa kit Typical Testing Data/Standard Curve (for reference only) image
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NCBI/Uniprot data below describe general gene information for HEXA. It may not necessarily be applicable to this product.
 NCBI GI #    67514549
 NCBI GeneID    15211
 NCBI Accession #    NP_034551.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_010421.4 [Other Products]
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 UniProt Primary Accession #    P29416 [Other Products]
 UniProt Secondary Accession #    Q64246; Q91XG3 [Other Products]
 UniProt Related Accession #    P29416 [Other Products]
 Molecular Weight    60,613 Da
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 NCBI Official Full Name    beta-hexosaminidase subunit alpha
 NCBI Official Synonym Full Names    hexosaminidase A
 NCBI Official Symbol    Hexa [Similar Products]
 NCBI Official Synonym Symbols   

Hex-1

[Similar Products]
 NCBI Protein Information    beta-hexosaminidase subunit alpha; hexosaminidase subunit A; beta-N-acetylhexosaminidase subunit alpha; N-acetyl-beta-glucosaminidase subunit alpha
 UniProt Protein Name    Beta-hexosaminidase subunit alpha
 UniProt Synonym Protein Names   

Beta-N-acetylhexosaminidase subunit alpha; Hexosaminidase subunit A; N-acetyl-beta-glucosaminidase subunit alpha

 UniProt Gene Name    Hexa [Similar Products]
 UniProt Synonym Gene Names    Hexosaminidase subunit A [Similar Products]
 UniProt Entry Name    HEXA_MOUSE
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 UniProt Comments for HEXA    Function: Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.

Catalytic activity: Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.
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 Research Articles on HEXA    1. Neu4 is not the only sialidase contributing to the metabolic bypass in Hexa(-/-) mice.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with HEXA elisa kitPathways associated with HEXA elisa kit
 Reference Product  PubMed Publications
 Hexb elisa kit  >79 publications with HEXA and Hexb
 Gm2a elisa kit  >9 publications with HEXA and Gm2a
 Naga elisa kit  >4 publications with HEXA and Naga
 Gusb elisa kit  >3 publications with HEXA and Gusb
 Glb1 elisa kit  >2 publications with HEXA and Glb1
 Neu4 elisa kit  >1 publications with HEXA and Neu4
 Products by Pathway  Pathway Diagram
 Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies  Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
 Amino Sugar And Nucleotide Sugar Metabolism Pathway antibodies  Amino Sugar And Nucleotide Sugar Metabolism Pathway Diagram
 CS/DS Degradation Pathway antibodies  CS/DS Degradation Pathway Diagram
 Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway antibodies  Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway Diagram
 Disease Pathway antibodies  Disease Pathway Diagram
 Glycogen Storage Diseases Pathway antibodies  Glycogen Storage Diseases Pathway Diagram
 Glycosaminoglycan Degradation Pathway antibodies  Glycosaminoglycan Degradation Pathway Diagram
 Glycosaminoglycan Degradation Pathway antibodies  Glycosaminoglycan Degradation Pathway Diagram
 Glycosaminoglycan Metabolism Pathway antibodies  Glycosaminoglycan Metabolism Pathway Diagram
 Glycosphingolipid Biosynthesis - Ganglio Series Pathway antibodies  Glycosphingolipid Biosynthesis - Ganglio Series Pathway Diagram
Diseases associated with HEXA elisa kitOrgans/Tissues associated with HEXA elisa kit
 Disease Name  Pubmed Publications
 Tay-Sachs Disease Antibodies  >131 publications with HEXA and Tay-Sachs Disease
 Hepatitis Antibodies  >60 publications with HEXA and Hepatitis
 Liver Diseases Antibodies  >38 publications with HEXA and Liver Diseases
 Inflammation Antibodies  >36 publications with HEXA and Inflammation
 Carcinoma Antibodies  >33 publications with HEXA and Carcinoma
 Death Antibodies  >29 publications with HEXA and Death
 Necrosis Antibodies  >27 publications with HEXA and Necrosis
 Poisoning Antibodies  >22 publications with HEXA and Poisoning
 Cardiovascular Diseases Antibodies  >20 publications with HEXA and Cardiovascular Diseases
 Kidney Diseases Antibodies  >19 publications with HEXA and Kidney Diseases
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >281 publications with HEXA and Blood
 Liver Antibodies  >140 publications with HEXA and Liver
 Brain Antibodies  >105 publications with HEXA and Brain
 Kidney Antibodies  >65 publications with HEXA and Kidney
 Lung Antibodies  >40 publications with HEXA and Lung
 Intestine Antibodies  >39 publications with HEXA and Intestine
 Testis Antibodies  >18 publications with HEXA and Testis
 Stomach Antibodies  >15 publications with HEXA and Stomach
 Placenta Antibodies  >12 publications with HEXA and Placenta
 Eye Antibodies  >12 publications with HEXA and Eye
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