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HIST2H2BB elisa kit :: Mouse histone cluster 2, H2bb ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9341261 HIST2H2BB elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

histone cluster 2, H2bb (HIST2H2BB), ELISA Kit

 Also Known As   

Mouse Histone H2B type 2-B, HIST2H2BB ELISA Kit

 Product Synonym Names    Mouse Histone H2B type 2-B (HIST2H2BB) ELISA kit; histone cluster 2; H2bb
 Product Gene Name   

HIST2H2BB elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q64525
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HIST2H2BB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HIST2H2BB purchase    MBS9341261 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the histone cluster 2, H2bb (HIST2H2BB) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing HIST2H2BB. The ELISA analytical biochemical technique of the MBS9341261 kit is based on HIST2H2BB antibody-HIST2H2BB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HIST2H2BB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HIST2H2BB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for HIST2H2BB. It may not necessarily be applicable to this product.
 NCBI GI #    68226433
 NCBI GeneID    319189
 NCBI Accession #    NP_783597.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_175666.2 [Other Products]
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 UniProt Primary Accession #    Q64525 [Other Products]
 UniProt Related Accession #    Q64525 [Other Products]
 Molecular Weight    13,920 Da
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 NCBI Official Full Name    histone H2B type 2-B
 NCBI Official Synonym Full Names    histone cluster 2, H2bb
 NCBI Official Symbol    Hist2h2bb [Similar Products]
 NCBI Official Synonym Symbols   
H2b-616
[Similar Products]
 NCBI Protein Information    histone H2B type 2-B; H2b 616; histone 2, H2bb
 UniProt Protein Name    Histone H2B type 2-B
 UniProt Synonym Protein Names   
H2b 616
 Protein Family    Histone
 UniProt Gene Name    Hist2h2bb [Similar Products]
 UniProt Entry Name    H2B2B_MOUSE
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 NCBI Summary for HIST2H2BB    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family. [provided by RefSeq, Mar 2014]
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 UniProt Comments for HIST2H2BB    H2B1H: a core component of the nucleoosome. The nucleosome, a basic organizational unit of chromosomal DNA, is octrameric, consisting of two molecules each of histones H2B, H2A, H3, H4. The octamer wraps approximately 147 bp of DNA. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Protein type: DNA-binding

Cellular Component: nucleus

Molecular Function: DNA binding

Biological Process: nucleosome assembly
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 Research Articles on HIST2H2BB    1. Autoimmunity to isoAsp H2B suggests that this form of the autoantigen may be critical in the induction of anti-histone autoantibodies in murine models of human SLE.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with HIST2H2BB elisa kit
 Products by Pathway  Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Alcoholism Pathway antibodies  Alcoholism Pathway Diagram
 Systemic Lupus Erythematosus Pathway antibodies  Systemic Lupus Erythematosus Pathway Diagram
 Systemic Lupus Erythematosus Pathway antibodies  Systemic Lupus Erythematosus Pathway Diagram
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