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HIF3A elisa kit :: Mouse hypoxia inducible factor 3, alpha subunit ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9319185 HIF3A elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

hypoxia inducible factor 3, alpha subunit (HIF3A), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Hypoxia-inducible factor 3-alpha, HIF3A ELISA Kit

 Product Synonym Names    Mouse Hypoxia-inducible factor 3-alpha (HIF3A) ELISA kit; HIF-3A; HIF-3A2; HIF-3A4; IPAS; MOP7; PASD7; bHLHe17; hypoxia-inducible factor-3 alpha 4; inhibitory PAS domain protein; hypoxia inducible factor 3; alpha subunit
 Product Gene Name   

HIF3A elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q0VBL6
 Species Reactivity    Mouse
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Assay Type    Quantitative Sandwich
 Detection Range    6.25 pg/ml - 200 pg/ml
 Sensitivity    1.0 pg/ml
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of HIF3A elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for HIF3A purchase    MBS9319185 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the hypoxia inducible factor 3, alpha subunit (HIF3A) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 6.25 pg/ml - 200 pg/ml in biological research samples containing HIF3A, with an estimated sensitivity of 1.0 pg/ml. The ELISA analytical biochemical technique of the MBS9319185 kit is based on HIF3A antibody-HIF3A antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect HIF3A antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, HIF3A. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for HIF3A elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of HIF3A (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9319185. Click to request current manual
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NCBI/Uniprot data below describe general gene information for HIF3A. It may not necessarily be applicable to this product.
 NCBI GI #    170295859
 NCBI GeneID    53417
 NCBI Accession #    NP_058564.2 [Other Products]
 NCBI GenBank Nucleotide #    NM_016868.3 [Other Products]
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 UniProt Primary Accession #    Q0VBL6 [Other Products]
 UniProt Secondary Accession #    Q3UN40; Q8VHR1; Q9QX54; Q9Z2I5; E9QLB1 [Other Products]
 UniProt Related Accession #    Q0VBL6 [Other Products]
 Molecular Weight    73,044 Da
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 NCBI Official Full Name    hypoxia-inducible factor 3-alpha isoform 2
 NCBI Official Synonym Full Names    hypoxia inducible factor 3, alpha subunit
 NCBI Official Symbol    Hif3a [Similar Products]
 NCBI Official Synonym Symbols   
Ipas; MOP7; NEPAS; bHLHe17
[Similar Products]
 NCBI Protein Information    hypoxia-inducible factor 3-alpha; HIF3-alpha; HIF-3-alpha; HIF3-alpha-1; member of PAS protein 7; neonatal and embryonic PAS; inhibitory PAS domain protein; hypoxia inducible factor three alpha; basic-helix-loop-helix-PAS protein MOP7
 UniProt Protein Name    Hypoxia-inducible factor 3-alpha
 UniProt Synonym Protein Names   
Basic-helix-loop-helix-PAS protein MOP7; HIF3-alpha-1; Inhibitory PAS domain protein; IPAS; Member of PAS protein 7
 Protein Family    Hypoxia-inducible factor
 UniProt Gene Name    Hif3a [Similar Products]
 UniProt Synonym Gene Names    Mop7; HIF-3-alpha; HIF3-alpha; IPAS [Similar Products]
 UniProt Entry Name    HIF3A_MOUSE
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 UniProt Comments for HIF3A    HIF3A: Involved in adaptive response to hypoxia. Suppresses hypoxia-inducible expression of HIF1A and EPAS1. Binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE. Isoform 4 has a dominant-negative function of inactivating HIF1A-mediated transcription. Isoform 4 attenuates the binding of HIF1A to hypoxia-responsive elements (HRE), thus inhibiting HRE-driven transcription. Hypoxia induces down-regulation of isoform 4, leading to activation of HIF1A in hypoxia. Conversely, upon restoring normoxia, the expression of isoform 4 increases and thereby secure an inhibition of HIF1A activity. Isoform 4 may be a negative regulator of hypoxia-inducible gene expression in the kidney and may be involved in renal tumorigenesis. Functions as an inhibitor of angiogenesis in the cornea. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Tumor suppressor; Transcription factor

Cellular Component: mitochondrion; cytoplasm; nuclear speck; nucleus

Molecular Function: protein dimerization activity; protein binding; signal transducer activity; DNA binding; transcription coactivator activity; transcription corepressor activity; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription, DNA-dependent; response to hypoxia; positive regulation of transcription from RNA polymerase II promoter; signal transduction
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 Research Articles on HIF3A    1. Anoxia preconditioning increases anti-ischemic neuronal resistance which to a certain extent correlates with the changes of HIF-1alpha and HIF-3alpha expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Diseases associated with HIF3A elisa kitOrgans/Tissues associated with HIF3A elisa kit
 Disease Name  Pubmed Publications
 Nervous System Diseases Antibodies  >6 publications with HIF3A and Nervous System Diseases
 Cardiovascular Diseases Antibodies  >6 publications with HIF3A and Cardiovascular Diseases
 Kidney Diseases Antibodies  >5 publications with HIF3A and Kidney Diseases
 Hypertension Antibodies  >5 publications with HIF3A and Hypertension
 Carcinoma Antibodies  >4 publications with HIF3A and Carcinoma
 Lung Diseases Antibodies  >4 publications with HIF3A and Lung Diseases
 Central Nervous System Diseases Antibodies  >2 publications with HIF3A and Central Nervous System Diseases
 Heart Diseases Antibodies  >2 publications with HIF3A and Heart Diseases
 Cardiomyopathies Antibodies  >2 publications with HIF3A and Cardiomyopathies
 Myocardial Ischemia Antibodies  >2 publications with HIF3A and Myocardial Ischemia
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >15 publications with HIF3A and Lung
 Kidney Antibodies  >9 publications with HIF3A and Kidney
 Brain Antibodies  >8 publications with HIF3A and Brain
 Eye Antibodies  >3 publications with HIF3A and Eye
 Embryonic Tissue Antibodies  >3 publications with HIF3A and Embryonic Tissue
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