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INH-B elisa kit :: Mouse inhibin B ELISA Kit

Scan QR to view Datasheet Catalog #    MBS700883
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $575 +1 FREE 8GB USB
96-Strip-Wells  /  $835 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,040 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,755 +7 FREE 8GB USB
 
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 Product Name   

inhibin B (INH-B), ELISA Kit

★Popular Item★
 Also Known As   

Mouse inhibin B, INH-B ELISA Kit

 Product Synonym Names    Mouse inhibin B; INH-B ELISA Kit; EDF; FRP; FSH-releasing protein; Inhibin; beta-1; OTTHUMP00000207260; erythroid differentiation factor; follicle-stimulating hormone-releasing protein; inhibin beta A; inhibin; beta A (activin A; activin; inhibin B
 Product Gene Name   

INH-B elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS700883 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for Q04998
 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Mouse INH-B. No significant cross-reactivity or interference between Mouse INH-B and analogues was observed.
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 Detection Range    0.8 pg/ml-200 pg/ml
 Sensitivity    0.2 pg/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of INH-B elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for INH-B purchase    MBS700883 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the inhibin B (INH-B) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.8 pg/ml-200 pg/ml in biological research samples containing INH-B, with an estimated sensitivity of 0.2 pg/ml. The ELISA analytical biochemical technique of the MBS700883 kit is based on INH-B antibody-INH-B antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect INH-B antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, INH-B. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for INH-B elisa kit

   Introduction: Inhibin is a peptide that is an inhibitor of FSH synthesis and secretion, and participates in the regulation of the menstrual cycle. Inhibin contains an alpha and beta subunit linked by disulfidebonds. Two forms of inhibin differ in their beta subunits (A or B), while their alpha subunits are identical. Inhibin belongs to the transforming growth factor-beta (TGF-beta) superfamily. In women, FSH stimulates the secretion of inhibin from the granulosa cells of the ovarian follicles in ovary. In turn, inhibin suppresses FSH.Inhibin secretion is diminished by GnRH, and enhanced by insulin-like growth factor-1 (IGF-1). Inhibins have been defined based on their activity of suppressing pituitary gonadotropin secretion. Thus, the serum concentrations of Inhibin B and FSH are inversely correlated, and at low serum levels of Inhibin B, FSH concentration goes up. Inhibin B serum concentration increases gradually in the follicular phase to a broad peak at 7 days prior to the LH surge, and may constitute the limiting factor for the duration of the inter-cycle FSH rise. A decrease and a second peak follow this peak one-day past the LH surge. Most of the serum Inhibin B concentration originates from large follicles, since such follicles secrete 10 fold higher concentrations than do the small follicles. Inhibin B concentrations drop to a very low concentration at the luteal phase, and is undetectable during pregnancy.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with goat-anti-rabbit antibody. Standards or samples are then added to the appropriate microtiter plate wells with a Horseradish Peroxidase (HRP)-conjugated INH-B and antibody preparation specific for INH-B, and incubated. Then substrate solutions are added to each well. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of INH-B in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of INH-B elisa kit    INH-B elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS700883. Click to request current manual
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NCBI/Uniprot data below describe general gene information for INH-B. It may not necessarily be applicable to this product.
 NCBI GI #    6680451
 NCBI GeneID    16323
 NCBI Accession #    NP_032406.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_008380.1 [Other Products]
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 UniProt Primary Accession #    Q04998 [Other Products]
 UniProt Related Accession #    Q04998 [Other Products]
 Molecular Weight    47,392 Da
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 NCBI Official Full Name    inhibin beta A chain
 NCBI Official Synonym Full Names    inhibin beta-A
 NCBI Official Symbol    Inhba [Similar Products]
 NCBI Protein Information    inhibin beta A chain; activin beta-A chain
 UniProt Protein Name    Inhibin beta A chain
 UniProt Synonym Protein Names   
Activin beta-A chain
 Protein Family    Inhibin
 UniProt Gene Name    Inhba [Similar Products]
 UniProt Entry Name    INHBA_MOUSE
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 UniProt Comments for INH-B    Function: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
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 Research Articles on INH-B    1. the Activin/ALK4 pathway directly recruits PTP1B and stimulates its release from the endoplasmic reticulum through ALK4-mediated cleavage.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with INH-B elisa kitPathways associated with INH-B elisa kit
 Reference Product  PubMed Publications
 INHBB elisa kit  >19 publications with INH-B and INHBB
 INHA elisa kit  >13 publications with INH-B and INHA
 FST elisa kit  >8 publications with INH-B and FST
 INHBC elisa kit  >1 publications with INH-B and INHBC
 IGFBP7 elisa kit  >1 publications with INH-B and IGFBP7
 FSTL3 elisa kit  >1 publications with INH-B and FSTL3
 ACVR2B elisa kit  >1 publications with INH-B and ACVR2B
 ACVR1 elisa kit  >1 publications with INH-B and ACVR1
 Products by Pathway  Pathway Diagram
 Antagonism Of Activin By Follistatin Pathway antibodies  Antagonism Of Activin By Follistatin Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Glycoprotein Hormones Pathway antibodies  Glycoprotein Hormones Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Peptide Hormone Biosynthesis Pathway antibodies  Peptide Hormone Biosynthesis Pathway Diagram
 Peptide Hormone Metabolism Pathway antibodies  Peptide Hormone Metabolism Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By Activin Pathway antibodies  Signaling By Activin Pathway Diagram
 TGF Beta Signaling Pathway antibodies  TGF Beta Signaling Pathway Diagram
Diseases associated with INH-B elisa kitOrgans/Tissues associated with INH-B elisa kit
 Disease Name  Pubmed Publications
 Necrosis Antibodies  >7 publications with INH-B and Necrosis
 Adenocarcinoma Antibodies  >7 publications with INH-B and Adenocarcinoma
 Kidney Diseases Antibodies  >5 publications with INH-B and Kidney Diseases
 Disease Models, Animal Antibodies  >5 publications with INH-B and Disease Models, Animal
 Inflammation Antibodies  >4 publications with INH-B and Inflammation
 Lung Neoplasms Antibodies  >3 publications with INH-B and Lung Neoplasms
 Cell Transformation, Neoplastic Antibodies  >3 publications with INH-B and Cell Transformation, Neoplastic
 Pre-Eclampsia Antibodies  >3 publications with INH-B and Pre-Eclampsia
 Cardiovascular Diseases Antibodies  >2 publications with INH-B and Cardiovascular Diseases
 Ovarian Neoplasms Antibodies  >2 publications with INH-B and Ovarian Neoplasms
 Organ/Tissue Name  Pubmed Publications
 Ovary Antibodies  >19 publications with INH-B and Ovary
 Bone Antibodies  >13 publications with INH-B and Bone
 Blood Antibodies  >12 publications with INH-B and Blood
 Lung Antibodies  >6 publications with INH-B and Lung
 Skin Antibodies  >4 publications with INH-B and Skin
 Kidney Antibodies  >4 publications with INH-B and Kidney
 Brain Antibodies  >4 publications with INH-B and Brain
 Stomach Antibodies  >4 publications with INH-B and Stomach
 Vascular Antibodies  >3 publications with INH-B and Vascular
 Liver Antibodies  >3 publications with INH-B and Liver
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