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IL2RG elisa kit :: Mouse interleukin 2 receptor, gamma (severe combined immunodeficiency) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS908334 IL2RG elisa kit
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

interleukin 2 receptor, gamma (severe combined immunodeficiency) (IL2RG), ELISA Kit

 Also Known As   

Mouse Cytokine receptor common subunit gamma, IL2RG ELISA Kit

 Product Synonym Names    Mouse Cytokine receptor common subunit gamma (IL2RG) ELISA kit; CD132; IMD4; SCIDX; SCIDX1; common cytokine receptor gamma chain; interleukin 2 receptor gamma chain; interleukin 2 receptor; gamma; interleukin 2 receptor; gamma (severe combined immunodeficiency)
 Product Gene Name   

IL2RG elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P34902
 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Mouse IL2RG. No significant cross-reactivity or interference between Mouse IL2RG and analogues was observed.
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 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of IL2RG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for IL2RG purchase    MBS908334 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the interleukin 2 receptor, gamma (severe combined immunodeficiency) (IL2RG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing IL2RG. The ELISA analytical biochemical technique of the MBS908334 kit is based on IL2RG antibody-IL2RG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect IL2RG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, IL2RG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for IL2RG. It may not necessarily be applicable to this product.
 NCBI GI #    7305181
 NCBI GeneID    16186
 NCBI Accession #    NP_038591.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_013563.3 [Other Products]
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 UniProt Primary Accession #    P34902 [Other Products]
 UniProt Related Accession #    P34902 [Other Products]
 Molecular Weight    42,241 Da
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 NCBI Official Full Name    cytokine receptor common subunit gamma
 NCBI Official Synonym Full Names    interleukin 2 receptor, gamma chain
 NCBI Official Symbol    Il2rg [Similar Products]
 NCBI Official Synonym Symbols   
gc; [g]c; CD132; gamma(c)
[Similar Products]
 NCBI Protein Information    cytokine receptor common subunit gamma; p64; IL-2RG; gammaC; gamma C receptor; common gamma chain; IL-2R subunit gamma; IL-2 receptor subunit gamma; interleukin-2 receptor subunit gamma; common cytokine receptor gamma chain variant b
 UniProt Protein Name    Cytokine receptor common subunit gamma
 UniProt Synonym Protein Names   
Interleukin-2 receptor subunit gamma; IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG; gammaC; p64; CD_antigen: CD132
 Protein Family    Cytokine receptor
 UniProt Gene Name    Il2rg [Similar Products]
 UniProt Synonym Gene Names    IL-2 receptor subunit gamma; IL-2R subunit gamma; IL-2RG [Similar Products]
 UniProt Entry Name    IL2RG_MOUSE
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 NCBI Summary for IL2RG    This gene encodes a transmembrane protein that is a common subunit of several interleukin receptor complexes. These receptors are comprised of alpha and beta subunits in addition to this gamma subunit. Signalling through this pathway in important in immune cell differentiation and function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
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 UniProt Comments for IL2RG    IL2RG: Common subunit for the receptors for a variety of interleukins. Defects in IL2RG are the cause of severe combined immunodeficiency X-linked T-cell-negative/B-cell-positive/NK-cell- negative (XSCID); also known as agammaglobulinemia Swiss type. A form of severe combined immunodeficiency (SCID), a genetically and clinically heterogeneous group of rare congenital disorders characterized by impairment of both humoral and cell- mediated immunity, leukopenia, and low or absent antibody levels. Patients present in infancy recurrent, persistent infections by opportunistic organisms. The common characteristic of all types of SCID is absence of T-cell-mediated cellular immunity due to a defect in T-cell development. Defects in IL2RG are the cause of X-linked combined immunodeficiency (XCID). XCID is a less severe form of X-linked immunodeficiency with a less severe degree of deficiency in cellular and humoral immunity than that seen in XSCID. Belongs to the type I cytokine receptor family. Type 5 subfamily.

Protein type: Receptor, cytokine; Membrane protein, integral

Cellular Component: cell surface; membrane; integral to membrane; external side of plasma membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-7 binding; interleukin-2 binding

Biological Process: positive regulation of T cell differentiation in the thymus; positive regulation of lymphocyte differentiation; regulation of gene expression; positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation; positive regulation of B cell differentiation
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 Research Articles on IL2RG    1. Human colon cancer xenografts propagated in NSG and NRG mice maintain structural fidelity while replacing human stromal cells with murine stromal cells.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with IL2RG elisa kitDiseases associated with IL2RG elisa kit
 Products by Pathway  Pathway Diagram
 Cytokine Signaling In Immune System Pathway antibodies  Cytokine Signaling In Immune System Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 Endocytosis Pathway antibodies  Endocytosis Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 IL-2 Signaling Pathway antibodies  IL-2 Signaling Pathway Diagram
 IL-4 Signaling Pathway antibodies  IL-4 Signaling Pathway Diagram
 IL-7 Signaling Pathway antibodies  IL-7 Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >127 publications with IL2RG and Neoplasms
 Inflammation Antibodies  >46 publications with IL2RG and Inflammation
 Severe combined immunodeficiency, X-linked Antibodies  >39 publications with IL2RG and Severe combined immunodeficiency, X-linked
 COMBINED IMMUNODEFICIENCY, X-LINKED Antibodies  >39 publications with IL2RG and COMBINED IMMUNODEFICIENCY, X-LINKED
 Necrosis Antibodies  >26 publications with IL2RG and Necrosis
 Autoimmune Diseases Antibodies  >20 publications with IL2RG and Autoimmune Diseases
 Neoplasms, Experimental Antibodies  >16 publications with IL2RG and Neoplasms, Experimental
 Carcinoma Antibodies  >15 publications with IL2RG and Carcinoma
 Leukopenia Antibodies  >14 publications with IL2RG and Leukopenia
 Liver Diseases Antibodies  >13 publications with IL2RG and Liver Diseases
Organs/Tissues associated with IL2RG elisa kit
 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >387 publications with IL2RG and Blood
 Other Antibodies  >102 publications with IL2RG and Other
 Bone Antibodies  >94 publications with IL2RG and Bone
 Bone Marrow Antibodies  >86 publications with IL2RG and Bone Marrow
 Spleen Antibodies  >53 publications with IL2RG and Spleen
 Thymus Antibodies  >51 publications with IL2RG and Thymus
 Liver Antibodies  >43 publications with IL2RG and Liver
 Lung Antibodies  >32 publications with IL2RG and Lung
 Skin Antibodies  >22 publications with IL2RG and Skin
 Heart Antibodies  >19 publications with IL2RG and Heart
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