NP_001234913.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
70,149 Da
NCBI Official Full Name
plastin-2
NCBI Official Synonym Full Names
lymphocyte cytosolic protein 1
NCBI Official Synonym Symbols
Pls2; pp65; LCP-1; AW536232; D14Ertd310e [Similar Products]
NCBI Protein Information
plastin-2; L-fimbrin; plastin 2, L; 65 kDa macrophage protein; L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (PP65)
UniProt Protein Name
Plastin-2
UniProt Synonym Protein Names
65 kDa macrophage protein; L-plastin; Lymphocyte cytosolic protein 1; LCP-1; pp65
UniProt Synonym Gene Names
UniProt Entry Name
PLSL_MOUSE
UniProt Comments for LCP1
L-plastin: Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. Monomer. Interacts with AIF1. Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T- lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells.
Protein type: Actin-binding; Motility/polarity/chemotaxis
Cellular Component: extracellular space; focal adhesion; actin filament bundle; actin filament; cytosol; actin cytoskeleton; ruffle; cytoskeleton; cell projection; membrane; cytoplasm; plasma membrane; stress fiber; cell junction; phagocytic cup; filopodium
Molecular Function: actin filament binding; identical protein binding; protein binding; metal ion binding; calcium ion binding; actin binding
Biological Process: actin filament bundle formation; cell migration; regulation of intracellular protein transport; response to wounding; T cell activation during immune response
Research Articles on LCP1
Precautions
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Diseases associated with LCP1 elisa kit
Organs/Tissues associated with LCP1 elisa kit
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