NP_084120.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,170 Da
NCBI Official Full Name
melanocortin-2 receptor accessory protein
NCBI Official Synonym Full Names
melanocortin 2 receptor accessory protein
NCBI Protein Information
melanocortin-2 receptor accessory protein; fat tissue-specific low MW protein; fat cell-specific low molecular weight protein
UniProt Protein Name
Melanocortin-2 receptor accessory protein
UniProt Synonym Protein Names
Fat cell-specific low molecular weight protein; Fat tissue-specific low MW protein
UniProt Synonym Gene Names
UniProt Entry Name
MRAP_MOUSE
UniProt Comments for MRAP
MRAP: Required for MC2R expression in certain cell types, suggesting that it is involved in the processing, trafficking or function of MC2R. May be involved in the intracellular trafficking pathways in adipocyte cells. Defects in MRAP are the cause of glucocorticoid deficiency type 2 (GCCD2); also known as familial glucocorticoid deficiency type 2 (FGD2). GCCD2 is an autosomal recessive disorder due to congenital insensitivity or resistance to adrenocorticotropin (ACTH). It is characterized by progressive primary adrenal insufficiency, without mineralocorticoid deficiency. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Cellular Component: membrane; endoplasmic reticulum; integral to membrane; plasma membrane
Molecular Function: type 5 melanocortin receptor binding; type 3 melanocortin receptor binding; type 4 melanocortin receptor binding; adrenocorticotropin hormone receptor binding
Biological Process: positive regulation of cAMP biosynthetic process; brown fat cell differentiation
Research Articles on MRAP
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Products associated with MRAP elisa kit
Diseases associated with MRAP elisa kit
Organs/Tissues associated with MRAP elisa kit
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