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MS4A2 elisa kit :: Mouse membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9320760 MS4A2 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) (MS4A2), ELISA Kit

 Also Known As   

Mouse High affinity immunoglobulin epsilon receptor subunit beta, MS4A2 ELISA Kit

 Product Synonym Names    Mouse High affinity immunoglobulin epsilon receptor subunit beta (MS4A2) ELISA kit; APY; ATOPY; FCER1B; FCERI; IGEL; IGER; IGHER; MS4A1; High affinity immunoglobulin epsilon receptor beta-subunit (FcERI) (IgE Fc receptor; beta-subunit) (Fc epsilon receptor I beta-chain) ; immunoglobu; membrane-spanning 4-domains; subfamily A; member 2 (Fc fragment of IgE; high affinity I; receptor for; beta polypeptide)
 Product Gene Name   

MS4A2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P20490
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MS4A2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MS4A2 purchase    MBS9320760 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) (MS4A2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MS4A2. The ELISA analytical biochemical technique of the MBS9320760 kit is based on MS4A2 antibody-MS4A2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MS4A2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MS4A2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for MS4A2. It may not necessarily be applicable to this product.
 NCBI GI #    7305049
 NCBI GeneID    14126
 NCBI Accession #    NP_038544.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_013516.2 [Other Products]
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 UniProt Primary Accession #    P20490 [Other Products]
 UniProt Related Accession #    P20490 [Other Products]
 Molecular Weight    25,963 Da
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 NCBI Official Full Name    high affinity immunoglobulin epsilon receptor subunit beta isoform a
 NCBI Official Synonym Full Names    membrane-spanning 4-domains, subfamily A, member 2
 NCBI Official Symbol    Ms4a2 [Similar Products]
 NCBI Official Synonym Symbols   
FcRB; Fce1b; Ms4a1; fcERI; Fcer1b; Fcrbeta
[Similar Products]
 NCBI Protein Information    high affinity immunoglobulin epsilon receptor subunit beta; fc epsilon receptor I beta-chain; membrane-spanning 4-domains, subfamily A, member 1; Fc receptor, IgE, high affinity I, beta polypeptide
 UniProt Protein Name    High affinity immunoglobulin epsilon receptor subunit beta
 UniProt Synonym Protein Names   
Fc epsilon receptor I beta-chain; IgE Fc receptor subunit beta; Membrane-spanning 4-domains subfamily A member 2
 Protein Family    High affinity immunoglobulin epsilon receptor
 UniProt Gene Name    Ms4a2 [Similar Products]
 UniProt Synonym Gene Names    Fce1b; Fcer1b; Ms4a1; FcERI [Similar Products]
 UniProt Entry Name    FCERB_MOUSE
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 NCBI Summary for MS4A2    This gene encodes a member of the membrane-spanning 4A family. The encoded protein is the beta subunit of the high affinity IgE receptor and is localized to the membrane. The encoded protein is required for full activation of mast cells, including the release of histamine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
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 UniProt Comments for MS4A2    FcER1B: High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy. Belongs to the MS4A family.

Protein type: Membrane protein, multi-pass; Receptor, misc.; Membrane protein, integral

Cellular Component: membrane; integral to plasma membrane; Fc-epsilon receptor I complex; integral to membrane; endosome; lipid raft; external side of plasma membrane

Molecular Function: phosphoprotein binding; SH2 domain binding; IgE binding; protein kinase binding; IgE receptor activity

Biological Process: cell surface receptor linked signal transduction; phospholipase C activation; protein kinase C activation; positive regulation of mast cell degranulation; immune response; inflammatory response; signal transduction; cytokine secretion; regulation of release of sequestered calcium ion into cytosol
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 Research Articles on MS4A2    1. chemotaxis toward antigen is controlled in mast cells by a cross-talk among FcepsilonRI, tetraspanin CD9, transmembrane adaptor proteins NTAL and LAT, and cytoskeleton-regulatory proteins of the ERM family
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with MS4A2 elisa kitDiseases associated with MS4A2 elisa kit
 Products by Pathway  Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Asthma Pathway antibodies  Asthma Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Fc Epsilon RI Signaling Pathway antibodies  Fc Epsilon RI Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Hypersensitivity Antibodies  >34 publications with MS4A2 and Hypersensitivity
 Hypersensitivity, Immediate Antibodies  >27 publications with MS4A2 and Hypersensitivity, Immediate
 Asthma Antibodies  >25 publications with MS4A2 and Asthma
 Respiratory Tract Diseases Antibodies  >20 publications with MS4A2 and Respiratory Tract Diseases
 Lung Diseases Antibodies  >20 publications with MS4A2 and Lung Diseases
 Respiratory Hypersensitivity Antibodies  >19 publications with MS4A2 and Respiratory Hypersensitivity
 Inflammation Antibodies  >6 publications with MS4A2 and Inflammation
 Skin Diseases Antibodies  >6 publications with MS4A2 and Skin Diseases
 Asthma, Aspirin-Induced Antibodies  >4 publications with MS4A2 and Asthma, Aspirin-Induced
 Necrosis Antibodies  >3 publications with MS4A2 and Necrosis
Organs/Tissues associated with MS4A2 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >4 publications with MS4A2 and Skin
 Kidney Antibodies  >1 publications with MS4A2 and Kidney
 Bone Marrow Antibodies  >1 publications with MS4A2 and Bone Marrow
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