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MAP3K12 elisa kit :: Mouse mitogen-activated protein kinase kinase kinase 12 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9323911 MAP3K12 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

mitogen-activated protein kinase kinase kinase 12 (MAP3K12), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Mitogen-activated protein kinase kinase kinase 12, MAP3K12 ELISA Kit

 Product Synonym Names    Mouse Mitogen-activated protein kinase kinase kinase 12 (MAP3K12) ELISA kit; DLK; MEKK12; MUK; ZPK; ZPKP1; dual leucine zipper kinase DLK; leucine zipper protein kinase; protein kinase MUK; zipper protein kinase; mitogen-activated protein kinase kinase kinase 12
 Product Gene Name   

MAP3K12 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q60700
 Species Reactivity    Mouse
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Serum, Plasma and Tissue Homogenate
 Assay Type    Sandwich
 Detection Range    0.25 ng/ml - 8 ng/ml.
 Sensitivity    0.1 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%.
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of MAP3K12 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for MAP3K12 purchase    MBS9323911 is a ready-to-use microwell, strip plate Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the mitogen-activated protein kinase kinase kinase 12 (MAP3K12) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 0.25 ng/ml - 8 ng/ml in biological research samples containing MAP3K12, with an estimated sensitivity of 0.1 ng/ml. The ELISA analytical biochemical technique of the MBS9323911 kit is based on MAP3K12 antibody-MAP3K12 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MAP3K12 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MAP3K12. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, Plasma and Tissue Homogenate. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Product Description specifically for MAP3K12 elisa kit

   Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MAPK12 (hereafter termed this analyte) in undiluted original Mouse serum, plasma and tissue homogenate samples.
Sample Manual Insert of MBS9323911. Click to request current manual
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NCBI/Uniprot data below describe general gene information for MAP3K12. It may not necessarily be applicable to this product.
 NCBI GI #    254692958
 NCBI GeneID    26404
 NCBI Accession #    NP_001157115.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001163643.1 [Other Products]
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 UniProt Primary Accession #    Q60700 [Other Products]
 UniProt Secondary Accession #    P70286; Q3TLL7; Q8C4N7; Q8CBX3; Q8CDL6 [Other Products]
 UniProt Related Accession #    Q60700 [Other Products]
 Molecular Weight    96,084 Da
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 NCBI Official Full Name    mitogen-activated protein kinase kinase kinase 12
 NCBI Official Synonym Full Names    mitogen-activated protein kinase kinase kinase 12
 NCBI Official Symbol    Map3k12 [Similar Products]
 NCBI Official Synonym Symbols   
DLK; MUK; Zpk
[Similar Products]
 NCBI Protein Information    mitogen-activated protein kinase kinase kinase 12; MAPK-upstream kinase; mixed lineage kinase; leucine-zipper protein kinase; zipper (leucine) protein kinase; dual leucine zipper bearing kinase; mitogen activated protein kinase kinase kinase 12
 UniProt Protein Name    Mitogen-activated protein kinase kinase kinase 12
 UniProt Synonym Protein Names   
Dual leucine zipper bearing kinase; DLK; Leucine-zipper protein kinase; ZPK; MAPK-upstream kinase; MUK; Mixed lineage kinase
 Protein Family    Mitogen-activated protein kinase kinase kinase
 UniProt Gene Name    Map3k12 [Similar Products]
 UniProt Synonym Gene Names    Zpk; DLK; ZPK; MUK [Similar Products]
 UniProt Entry Name    M3K12_MOUSE
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 UniProt Comments for MAP3K12    DLK: May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

Protein type: EC 2.7.11.25; Protein kinase, TKL; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; TKL group; MLK family; LZK subfamily

Cellular Component: growth cone; membrane; axon; cytoplasm; plasma membrane; cytosol

Molecular Function: transferase activity; protein serine/threonine kinase activity; protein homodimerization activity; MAP kinase kinase kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; protein kinase binding; ATP binding; protein kinase activity

Biological Process: peptidyl-serine phosphorylation; activation of MAPKK activity; protein amino acid autophosphorylation; histone phosphorylation; peptidyl-threonine phosphorylation; JNK cascade; phosphorylation; protein amino acid phosphorylation
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 Research Articles on MAP3K12    1. DLK-inducible knockouts displayed a modest increase in basal synaptic transmission but had an attenuation of the JNK/c-Jun stress response pathway activation and significantly reduced neuronal degeneration after kainic acid-induced seizures.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with MAP3K12 elisa kitDiseases associated with MAP3K12 elisa kit
 Products by Pathway  Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram
 MAPK Cascade Pathway antibodies  MAPK Cascade Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with MAP3K12 and Neoplasms
 Neuroblastoma Antibodies  >1 publications with MAP3K12 and Neuroblastoma
 Neuroectodermal Tumors Antibodies  >1 publications with MAP3K12 and Neuroectodermal Tumors
 Drug Toxicity Antibodies  >1 publications with MAP3K12 and Drug Toxicity
Organs/Tissues associated with MAP3K12 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >2 publications with MAP3K12 and Brain
 Kidney Antibodies  >1 publications with MAP3K12 and Kidney
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