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Mpl elisa kit :: Mouse myeloproliferative leukemia virus oncogene ELISA Kit

Scan QR to view Datasheet Catalog #    MBS2602853 Mpl elisa kit
Unit / Price
48-Strip-Wells  /  $275 +1 FREE 8GB USB
96-Strip-Wells  /  $435 +1 FREE 8GB USB
5x96-Strip-Wells  /  $1,755 +2 FREE 8GB USB
10x96-Strip-Wells  /  $3,150 +3 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

myeloproliferative leukemia virus oncogene (Mpl), ELISA Kit

 Also Known As   

Mouse Thrombopoietin receptor, MPL ELISA Kit

 Product Gene Name   

Mpl elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q08351
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of Mpl elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for Mpl purchase    MBS2602853 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the myeloproliferative leukemia virus oncogene (Mpl) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Mpl. The ELISA analytical biochemical technique of the MBS2602853 kit is based on Mpl antibody-Mpl antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Mpl antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Mpl. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for Mpl. It may not necessarily be applicable to this product.
 NCBI GI #    171846242
 NCBI GeneID    17480
 NCBI Accession #    NP_001116421.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001122949.2 [Other Products]
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 UniProt Primary Accession #    Q08351 [Other Products]
 UniProt Secondary Accession #    Q8BRX0; A6H8H6 [Other Products]
 UniProt Related Accession #    Q08351 [Other Products]
 Molecular Weight    69,788 Da [Similar Products]
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 NCBI Official Full Name    thrombopoietin receptor isoform 1
 NCBI Official Synonym Full Names    myeloproliferative leukemia virus oncogene
 NCBI Official Symbol    Mpl [Similar Products]
 NCBI Official Synonym Symbols   
CD110; TPO-R; c-mpl; hlb219
[Similar Products]
 NCBI Protein Information    thrombopoietin receptor; proto-oncogene c-Mpl; myeloproliferative leukemia protein
 UniProt Protein Name    Thrombopoietin receptor
 UniProt Synonym Protein Names   
Myeloproliferative leukemia protein; Proto-oncogene c-Mpl; CD_antigen: CD110
 Protein Family    Zinc metalloproteinase
 UniProt Gene Name    Mpl [Similar Products]
 UniProt Synonym Gene Names    Tpor; TPO-R [Similar Products]
 UniProt Entry Name    TPOR_MOUSE
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 UniProt Comments for Mpl    MPL: a hematopoietic receptor for thrombopoietin. Thrombopoietin is the major regulator of megakaryocytopoiesis and platelet formation. Dimerizes upon binding of thrombopoietin, leading to its phosphorylation and activation of JAKs and STATs. May represent a regulatory molecule specific for TPO-R-dependent immune responses. Two splice-variant isoforms have been described.

Protein type: Receptor, cytokine; Membrane protein, integral

Cellular Component: membrane; plasma membrane; integral to membrane

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor activity

Biological Process: homeostasis of number of cells; regulation of chemokine production
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 Research Articles on Mpl    1. Mpl expression on megakaryocytes and platelets is essential to prevent megakaryocytosis and myeloproliferation.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with Mpl elisa kitDiseases associated with Mpl elisa kit
 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Platelet Aggregation (Plug Formation) Pathway antibodies  Platelet Aggregation (Plug Formation) Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 PluriNetWork Pathway antibodies  PluriNetWork Pathway Diagram
 Disease Name  Pubmed Publications
 Bone Marrow Diseases Antibodies  >404 publications with Mpl and Bone Marrow Diseases
 Leukemia Antibodies  >299 publications with Mpl and Leukemia
 Thrombocytosis Antibodies  >195 publications with Mpl and Thrombocytosis
 Thrombocythemia, Essential Antibodies  >190 publications with Mpl and Thrombocythemia, Essential
 Leukemia, Myeloid Antibodies  >164 publications with Mpl and Leukemia, Myeloid
 Leukemia, Myeloid, Acute Antibodies  >117 publications with Mpl and Leukemia, Myeloid, Acute
 Cardiovascular Diseases Antibodies  >88 publications with Mpl and Cardiovascular Diseases
 Myelodysplastic Syndromes Antibodies  >65 publications with Mpl and Myelodysplastic Syndromes
 Necrosis Antibodies  >60 publications with Mpl and Necrosis
 Chromosome Aberrations Antibodies  >55 publications with Mpl and Chromosome Aberrations
Organs/Tissues associated with Mpl elisa kit
 Organ/Tissue Name  Pubmed Publications
 Bone Marrow Antibodies  >350 publications with Mpl and Bone Marrow
 Spleen Antibodies  >104 publications with Mpl and Spleen
 Mammary Gland Antibodies  >5 publications with Mpl and Mammary Gland
 Inner Ear Antibodies  >1 publications with Mpl and Inner Ear
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