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PITX2 elisa kit :: Mouse paired-like homeodomain 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9328365 PITX2 elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

paired-like homeodomain 2 (PITX2), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Pituitary homeobox 2, PITX2 ELISA Kit

 Product Synonym Names    Mouse Pituitary homeobox 2 (PITX2) ELISA kit; ARP1; Brx1; IDG2; IGDS; IGDS2; IHG2; IRID2; MGC111022; MGC20144; Otlx2; PTX2; RGS; RIEG; RIEG1; RS; OTTHUMP00000163736; all1-responsive gene 1; paired-like homeodomain transcription factor 2; pituitary; paired-like homeodomain 2
 Product Gene Name   

PITX2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for P97474
 Species Reactivity    Mouse
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 Specificity    No significant cross-reactivity or interference between this analyte and analogues is observed.
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 Samples    Body fluids, tissue homogenates, secretions or feces samples
 Assay Type    Quantitative Sandwich
 Detection Range    3.12 ng/ml - 100 ng/ml
 Sensitivity    1.0 ng/ml.
 Intra-assay Precision    Intra-assay CV (%) is less than 15%
 Inter-assay Precision    Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean 100].
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PITX2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PITX2 purchase    MBS9328365 is a ready-to-use microwell, strip plate Quantitative Sandwich ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the paired-like homeodomain 2 (PITX2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 3.12 ng/ml - 100 ng/ml in biological research samples containing PITX2, with an estimated sensitivity of 1.0 ng/ml. The ELISA analytical biochemical technique of the MBS9328365 kit is based on PITX2 antibody-PITX2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PITX2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PITX2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Body fluids, tissue homogenates, secretions or feces samples. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PITX2 elisa kit

   Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of PITX2 (hereafter termed "analyte") in undiluted original Mouse body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.
Sample Manual Insert of MBS9328365. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PITX2. It may not necessarily be applicable to this product.
 NCBI GI #    109948275
 NCBI GeneID    18741
 NCBI Accession #    NP_001035967.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001042502.2 [Other Products]
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 UniProt Primary Accession #    P97474 [Other Products]
 UniProt Secondary Accession #    O08646; O70336; P97933; Q9JLA0; Q9QXB8; Q9R1V9; Q9Z141 [Other Products]
 UniProt Related Accession #    P97474 [Other Products]
 Molecular Weight    35,321 Da
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 NCBI Official Full Name    pituitary homeobox 2 isoform c
 NCBI Official Synonym Full Names    paired-like homeodomain transcription factor 2
 NCBI Official Symbol    Pitx2 [Similar Products]
 NCBI Official Synonym Symbols   
Brx1; Ptx2; Rieg; Brx1b; Otlx2; Munc30; 9430085M16Rik
[Similar Products]
 NCBI Protein Information    pituitary homeobox 2; solurshin; BRX1 homeoprotein; ALL1-responsive protein ARP1; orthodenticle-like homeobox 2; paired-like homeodomain transcription factor Munc 30
 UniProt Protein Name    Pituitary homeobox 2
 UniProt Synonym Protein Names   
ALL1-responsive protein ARP1; BRX1 homeoprotein; Homeobox protein PITX2; Orthodenticle-like homeobox 2; Paired-like homeodomain transcription factor 2; Paired-like homeodomain transcription factor Munc 30; Solurshin
 Protein Family    Pituitary homeobox
 UniProt Gene Name    Pitx2 [Similar Products]
 UniProt Synonym Gene Names    Arp1; Brx1; Otlx2; Ptx2; Rgs [Similar Products]
 UniProt Entry Name    PITX2_MOUSE
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 UniProt Comments for PITX2    PITX2: Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform PTX2C is involved in left-right asymmetry the developing embryo. Defects in PITX2 are the cause of Axenfeld-Rieger syndrome type 1 (RIEG1); also known as Rieger syndrome type 1. RIEG1 is an autosomal dominant defect characterized by hypodontia (partial anodontia), anal stenosis, hypertelorism, mental deficiency, agenesis of the facial bones, with malformation of the anterior chamber of the eye. Defects in PITX2 are the cause of iridogoniodysgenesis type 2 (IRID2); also known as iridogoniodysgenesis syndrome 2 (IGDS2). It is an autosomal dominant inherited disease. Defects in PITX2 are a cause of Peters anomaly (PAN). It is a congenital defect of the anterior chamber of the eye. Defects in PITX2 are associated with ring dermoid of cornea (RDC). RDC is an autosomal dominantly inherited syndrome characterized by bilateral annular limbal dermoids with corneal and conjunctival extension. Belongs to the paired homeobox family. Bicoid subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation; DNA-binding; Transcription factor; Motility/polarity/chemotaxis

Cellular Component: nucleoplasm; transcription factor complex; cytoplasm; nucleus

Molecular Function: identical protein binding; protein binding; protein homodimerization activity; DNA binding; sequence-specific DNA binding; chromatin DNA binding; phosphoprotein binding; chromatin binding; transcription factor binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; atrial cardiac muscle morphogenesis; positive regulation of transcription, DNA-dependent; heart development; multicellular organismal development; ventricular cardiac muscle cell development; neuron migration; negative regulation of transcription from RNA polymerase II promoter; regulation of cell migration; embryonic hindlimb morphogenesis; cardiac muscle cell differentiation; odontogenesis; regulation of transcription, DNA-dependent; embryonic digestive tract morphogenesis; extraocular skeletal muscle development; vasculogenesis; hypothalamus cell migration; myoblast fusion; positive regulation of DNA binding; cardiac muscle development; spleen development; anatomical structure morphogenesis; skeletal muscle development; Wnt receptor signaling pathway; camera-type eye development; in utero embryonic development; embryonic camera-type eye development; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; patterning of blood vessels; organ morphogenesis; subthalamic nucleus development; pituitary gland development; positive regulation of transcription from RNA polymerase II promoter; determination of left/right symmetry; lung development
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 Research Articles on PITX2    1. During fetal myogenesis, Pitx2/3 control this redox state through the regulation of Nrf1 and of antioxidant pathways.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PITX2 elisa kitDiseases associated with PITX2 elisa kit
 Products by Pathway  Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 TGF-beta Signaling Pathway antibodies  TGF-beta Signaling Pathway Diagram
 Disease Name  Pubmed Publications
 Abnormalities, Multiple Antibodies  >52 publications with PITX2 and Abnormalities, Multiple
 Neoplasms Antibodies  >43 publications with PITX2 and Neoplasms
 Heart Defects, Congenital Antibodies  >38 publications with PITX2 and Heart Defects, Congenital
 Tooth Abnormalities Antibodies  >34 publications with PITX2 and Tooth Abnormalities
 Craniofacial Abnormalities Antibodies  >28 publications with PITX2 and Craniofacial Abnormalities
 Breast Neoplasms Antibodies  >16 publications with PITX2 and Breast Neoplasms
 Disease Models, Animal Antibodies  >12 publications with PITX2 and Disease Models, Animal
 Peters anomaly Antibodies  >8 publications with PITX2 and Peters anomaly
 Prostatic Diseases Antibodies  >7 publications with PITX2 and Prostatic Diseases
 Prostatic Neoplasms Antibodies  >7 publications with PITX2 and Prostatic Neoplasms
Organs/Tissues associated with PITX2 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >132 publications with PITX2 and Eye
 Embryonic Tissue Antibodies  >103 publications with PITX2 and Embryonic Tissue
 Brain Antibodies  >87 publications with PITX2 and Brain
 Pituitary Gland Antibodies  >52 publications with PITX2 and Pituitary Gland
 Skin Antibodies  >11 publications with PITX2 and Skin
 Molar Antibodies  >9 publications with PITX2 and Molar
 Liver Antibodies  >8 publications with PITX2 and Liver
 Tongue Antibodies  >4 publications with PITX2 and Tongue
 Testis Antibodies  >3 publications with PITX2 and Testis
 Extraembryonic Tissue Antibodies  >2 publications with PITX2 and Extraembryonic Tissue
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