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PLOD3 elisa kit :: Mouse procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9323195 PLOD3 elisa kit
Unit / Price
48-Strip-Wells  /  $470 +1 FREE 8GB USB
96-Strip-Wells  /  $680 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,100 +3 FREE 8GB USB
10x96-Strip-Wells  /  $6,095 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (PLOD3), ELISA Kit

 Also Known As   

Mouse Procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3, PLOD3 ELISA Kit

 Product Synonym Names    Mouse Procollagen-lysine; 2-oxoglutarate 5-dioxygenase 3 (PLOD3) ELISA kit; LH3; lysine hydroxylase 3; lysyl hydroxylase 3; procollagen-lysine; 2-oxoglutarate 5-dioxygenase 3
 Product Gene Name   

PLOD3 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q9R0E1
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PLOD3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PLOD3 purchase    MBS9323195 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (PLOD3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing PLOD3. The ELISA analytical biochemical technique of the MBS9323195 kit is based on PLOD3 antibody-PLOD3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PLOD3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PLOD3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for PLOD3. It may not necessarily be applicable to this product.
 NCBI GI #    6755110
 NCBI GeneID    26433
 NCBI Accession #    NP_036092.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_011962.3 [Other Products]
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 UniProt Primary Accession #    Q9R0E1 [Other Products]
 UniProt Secondary Accession #    Q542E0; Q9CYY9 [Other Products]
 UniProt Related Accession #    Q9R0E1 [Other Products]
 Molecular Weight    84,922 Da
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 NCBI Official Full Name    procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
 NCBI Official Synonym Full Names    procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
 NCBI Official Symbol    Plod3 [Similar Products]
 NCBI Official Synonym Symbols   
LH3; AI414586
[Similar Products]
 NCBI Protein Information    procollagen-lysine,2-oxoglutarate 5-dioxygenase 3; lysyl hydroxylase 2; lysyl hydroxylase 3
 UniProt Protein Name    Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
 UniProt Synonym Protein Names   
Lysyl hydroxylase 3; LH3
 Protein Family    Procollagen-lysine,2-oxoglutarate 5-dioxygenase
 UniProt Gene Name    Plod3 [Similar Products]
 UniProt Synonym Gene Names    LH3 [Similar Products]
 UniProt Entry Name    PLOD3_MOUSE
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 UniProt Comments for PLOD3    PLOD3: Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. Defects in PLOD3 are the cause of lysyl hydroxylase 3 deficiency (LH3 deficiency); also known as bone fragility with contractures arterial rupture and deafness. LH3 deficiency is a connective tissue disorder. The syndrome is characterized by congenital malformations severely affecting many tissues and organs and revealing features of several collagen disorders, most of them involving COL2A1 (type II collagen). The findings suggest that the failure of lysyl hydroxylation and hydroxylysyl carbohydrate addition, which affects many collagens, is the molecular basis of this syndrome.

Protein type: Endoplasmic reticulum; Oxidoreductase; EC 1.14.11.4; Amino Acid Metabolism - lysine degradation

Cellular Component: membrane; endoplasmic reticulum

Molecular Function: L-ascorbic acid binding; dioxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding; metal ion binding; procollagen-lysine 5-dioxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; oxidoreductase activity; procollagen glucosyltransferase activity

Biological Process: neural tube development; protein localization; collagen fibril organization; in utero embryonic development; epidermis morphogenesis; endothelial cell morphogenesis; vasodilation
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 Research Articles on PLOD3    1. LH3 is an important regulator of adiponectin biosynthesis, secretion and activity.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PLOD3 elisa kitDiseases associated with PLOD3 elisa kit
 Products by Pathway  Pathway Diagram
 Lysine Degradation Pathway antibodies  Lysine Degradation Pathway Diagram
 Lysine Degradation Pathway antibodies  Lysine Degradation Pathway Diagram
 Other Types Of O-glycan Biosynthesis Pathway antibodies  Other Types Of O-glycan Biosynthesis Pathway Diagram
 Other Types Of O-glycan Biosynthesis Pathway antibodies  Other Types Of O-glycan Biosynthesis Pathway Diagram
 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with PLOD3 and Neoplasms
 Adenocarcinoma Antibodies  >1 publications with PLOD3 and Adenocarcinoma
 Pancreatic Neoplasms Antibodies  >1 publications with PLOD3 and Pancreatic Neoplasms
 Breast Neoplasms Antibodies  >1 publications with PLOD3 and Breast Neoplasms
Organs/Tissues associated with PLOD3 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Bone Antibodies  >3 publications with PLOD3 and Bone
 Connective Tissue Antibodies  >2 publications with PLOD3 and Connective Tissue
 Skin Antibodies  >2 publications with PLOD3 and Skin
 Pancreas Antibodies  >1 publications with PLOD3 and Pancreas
 Adipose Tissue Antibodies  >1 publications with PLOD3 and Adipose Tissue
 Heart Antibodies  >1 publications with PLOD3 and Heart
 Bone Marrow Antibodies  >1 publications with PLOD3 and Bone Marrow
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