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PROK2 elisa kit :: Mouse prokineticin 2 ELISA Kit

Scan QR to view Datasheet Catalog #    MBS938170
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (Limit 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $495 +1 FREE 8GB USB
96-Strip-Wells  /  $710 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,705 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,145 +6 FREE 8GB USB
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

prokineticin 2 (PROK2), ELISA Kit

★Popular Item★
 Also Known As   

Mouse Prokineticin-2, PROK2 ELISA Kit

 Product Synonym Names    Mouse Prokineticin-2 (PROK2) ELISA kit; BV8; KAL4; MIT1; PK2; protein Bv8 homolog; prokineticin 2
 Product Gene Name   

PROK2 elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS938170 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for Q9QXU7
 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of mouse PROK2. No significant cross-reactivity or interference between mouse PROK2 and analogues was observed.
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 Samples    Serum, plasma, cell culture supernates, tissue homogenates.
 Assay Type    Sandwich (Quantitative)
 Detection Range    12.5 pg/ml-800 pg/ml.
 Sensitivity    3.12 pg/ml.
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
 Inter-assay Precision    Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of PROK2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for PROK2 purchase    MBS938170 is a ready-to-use microwell, strip plate Sandwich (Quantitative) ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the prokineticin 2 (PROK2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 12.5 pg/ml-800 pg/ml in biological research samples containing PROK2, with an estimated sensitivity of 3.12 pg/ml. The ELISA analytical biochemical technique of the MBS938170 kit is based on PROK2 antibody-PROK2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect PROK2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, PROK2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions such as Serum, plasma, cell culture supernates, tissue homogenates. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for PROK2 elisa kit

   Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for PROK2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any PROK2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PROK2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PROK2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
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 Typical Testing Data/Standard Curve (for reference only) of PROK2 elisa kit    PROK2 elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS938170. Click to request current manual
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NCBI/Uniprot data below describe general gene information for PROK2. It may not necessarily be applicable to this product.
 NCBI GI #    82830395
 NCBI GeneID    50501
 NCBI Accession #    NP_001032628.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001037539.2 [Other Products]
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 UniProt Primary Accession #    Q9QXU7 [Other Products]
 UniProt Secondary Accession #    Q9QXU5; Q9QXU6; B7ZMX7 [Other Products]
 UniProt Related Accession #    Q9QXU7 [Other Products]
 Molecular Weight    14,185 Da
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 NCBI Official Full Name    prokineticin-2 isoform 2
 NCBI Official Synonym Full Names    prokineticin 2
 NCBI Official Symbol    Prok2 [Similar Products]
 NCBI Official Synonym Symbols   
Bv8; PK2; Prok1
[Similar Products]
 NCBI Protein Information    prokineticin-2; prokineticin 1; protein Bv8 homolog; Bombina variegata 8 kD protein; Bombina variegata 8kDa protein; Bv 8 homolog (Bombina variegata)
 UniProt Protein Name    Prokineticin-2
 UniProt Synonym Protein Names   
Protein Bv8 homolog
 Protein Family    Prokineticin
 UniProt Gene Name    Prok2 [Similar Products]
 UniProt Synonym Gene Names    Bv8; PK2 [Similar Products]
 UniProt Entry Name    PROK2_MOUSE
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 UniProt Comments for PROK2    PROK2: May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle. Defects in PROK2 are the cause of Kallmann syndrome type 4 (KAL4); also known as hypogonadotropic hypogonadism and anosmia. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin- releasing hormone-synthesizing neurons. KAL4 patients have variable degrees of olfactory and reproductive dysfunction, but do not show any of the occasional clinical anomalies reported in Kallmann syndrome such as renal agenesis, cleft lip/palate, selective tooth agenesis, and bimanual synkinesis. Belongs to the AVIT (prokineticin) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular region

Molecular Function: G-protein-coupled receptor binding

Biological Process: circadian rhythm; cell proliferation; neuropeptide signaling pathway; rhythmic process; spermatogenesis; positive regulation of smooth muscle contraction; angiogenesis; chemotaxis; negative regulation of apoptosis
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 Research Articles on PROK2    1. PK2 plays an important role in energy intake and expenditure.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with PROK2 elisa kitDiseases associated with PROK2 elisa kit
 Products by Pathway  Pathway Diagram
 G Alpha (q) Signalling Events Pathway antibodies  G Alpha (q) Signalling Events Pathway Diagram
 GPCR Downstream Signaling Pathway antibodies  GPCR Downstream Signaling Pathway Diagram
 Signal Transduction Pathway antibodies  Signal Transduction Pathway Diagram
 Signaling By GPCR Pathway antibodies  Signaling By GPCR Pathway Diagram
 Disease Name  Pubmed Publications
 Hypogonadism Antibodies  >44 publications with PROK2 and Hypogonadism
 Kallmann Syndrome Antibodies  >40 publications with PROK2 and Kallmann Syndrome
 Neurologic Manifestations Antibodies  >19 publications with PROK2 and Neurologic Manifestations
 Sensation Disorders Antibodies  >11 publications with PROK2 and Sensation Disorders
 Pain Antibodies  >11 publications with PROK2 and Pain
 Neoplasms Antibodies  >10 publications with PROK2 and Neoplasms
 Inflammation Antibodies  >10 publications with PROK2 and Inflammation
 Hyperalgesia Antibodies  >8 publications with PROK2 and Hyperalgesia
 Heart Diseases Antibodies  >6 publications with PROK2 and Heart Diseases
 Myocardial Infarction Antibodies  >4 publications with PROK2 and Myocardial Infarction
Organs/Tissues associated with PROK2 elisa kit
 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >8 publications with PROK2 and Testis
 Inner Ear Antibodies  >2 publications with PROK2 and Inner Ear
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