NP_032797.3
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
44,851 Da
NCBI Official Full Name
P2X purinoceptor 1
NCBI Official Synonym Full Names
purinergic receptor P2X, ligand-gated ion channel, 1
NCBI Official Synonym Symbols
P2x; RP-2; Pdcd3; AI323649; BB122383 [Similar Products]
NCBI Protein Information
P2X purinoceptor 1; ATP receptor; P2X1 receptor; programmed cell death 3
UniProt Protein Name
P2X purinoceptor 1
UniProt Synonym Protein Names
ATP receptor; Purinergic receptor
UniProt Synonym Gene Names
UniProt Entry Name
P2RX1_MOUSE
UniProt Comments for P2RX1
P2X1: Ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle. Seems to be linked to apoptosis, by increasing the intracellular concentration of calcium in the presence of ATP, leading to programmed cell death. Belongs to the P2X receptor family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Channel, ligand-gated
Cellular Component: postsynaptic membrane; neuron projection; protein complex; membrane; cell; integral to plasma membrane; integral to membrane; plasma membrane; integral to nuclear inner membrane; lipid raft
Molecular Function: zinc ion binding; ion channel activity; drug binding; cation channel activity; ATP binding; purinergic nucleotide receptor activity; ATP-gated cation channel activity
Biological Process: caspase activation; regulation of smooth muscle contraction; platelet activation; vasoconstriction; synaptic transmission, glutamatergic; protein heterooligomerization; apoptosis; insemination; generation of action potential; regulation of calcium ion transport; response to ATP; response to organic substance; serotonin secretion by platelet; transport; regulation of vasoconstriction; regulation of blood pressure; regulation of vascular smooth muscle contraction; ceramide biosynthetic process; ion transport; positive regulation of ion transport; protein homooligomerization
Research Articles on P2RX1
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Pathways associated with P2RX1 elisa kit
Organs/Tissues associated with P2RX1 elisa kit
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