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RFXANK elisa kit :: Mouse regulatory factor X-associated ankyrin-containing protein ELISA Kit

Scan QR to view Datasheet Catalog #    MBS9323256 RFXANK elisa kit
Unit / Price
48-Strip-Wells  /  $435 +1 FREE 8GB USB
96-Strip-Wells  /  $600 +1 FREE 8GB USB
5x96-Strip-Wells  /  $2,650 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,205 +6 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

regulatory factor X-associated ankyrin-containing protein (RFXANK), ELISA Kit

 Also Known As   

Mouse DNA-binding protein RFXANK, RFXANK ELISA Kit

 Product Synonym Names    Mouse DNA-binding protein RFXANK (RFXANK) ELISA kit; ANKRA1; BLS; F14150_1; MGC138628; RFX-B; DNA-binding protein RFXANK; RFX-Bdelta4; ankyrin repeat-containing regulatory factor X-associated protein; regulatory factor X subunit B; regulatory factor X-associated ankyrin-containing protein
 Product Gene Name   

RFXANK elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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 Request for Current Manual Insert    Request Current Manual
 3D Structure    ModBase 3D Structure for Q9Z205
 Species Reactivity    Mouse
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 Preparation and Storage    Store all reagents at 2-8 degree C
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of RFXANK elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for RFXANK purchase    MBS9323256 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the regulatory factor X-associated ankyrin-containing protein (RFXANK) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing RFXANK. The ELISA analytical biochemical technique of the MBS9323256 kit is based on RFXANK antibody-RFXANK antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect RFXANK antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, RFXANK. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for RFXANK. It may not necessarily be applicable to this product.
 NCBI GI #    70980523
 NCBI GeneID    19727
 NCBI Accession #    NP_001020760.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_001025589.1 [Other Products]
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 UniProt Primary Accession #    Q9Z205 [Other Products]
 UniProt Related Accession #    Q9Z205 [Other Products]
 Molecular Weight    29,232 Da
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 NCBI Official Full Name    DNA-binding protein RFXANK isoform 2
 NCBI Official Synonym Full Names    regulatory factor X-associated ankyrin-containing protein
 NCBI Official Symbol    Rfxank [Similar Products]
 NCBI Official Synonym Symbols   
Tvl1
[Similar Products]
 NCBI Protein Information    DNA-binding protein RFXANK; RFX-B; regulatory factor X subunit B; ankyrin repeat-containing adapter protein Tvl-1
 UniProt Protein Name    DNA-binding protein RFXANK
 UniProt Synonym Protein Names   
Ankyrin repeat-containing adapter protein Tvl-1; Regulatory factor X subunit B; RFX-B; Regulatory factor X-associated ankyrin-containing protein
 Protein Family    DNA-binding protein
 UniProt Gene Name    Rfxank [Similar Products]
 UniProt Synonym Gene Names    Rfxb; Tvl1; RFX-B [Similar Products]
 UniProt Entry Name    RFXK_MOUSE
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 UniProt Comments for RFXANK    RFXANK: Activates transcription from class II MHC promoters. Activation requires the activity of the MHC class II transactivator (MHC2TA). May regulate other genes in the cell. RFX binds the X1 box of MHC-II promoters. Isoform RFX-B-delta5 is not involved in the positive regulation of MHC class II genes. Defects in RFXANK are a cause of bare lymphocyte syndrome type 2 (BLS2); also known as hereditary MHC class II deficiency or HLA class II-deficient combined immunodeficiency. BLS2 is a severe combined immunodeficiency disease with early onset. It is characterized by a profound defect in constitutive and interferon-gamma induced MHC II expression, absence of cellular and humoral T-cell response to antigen challenge, hypogammaglobulinemia and impaired antibody production. The consequence include extreme susceptibility to viral, bacterial and fungal infections. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Transcription, coactivator/corepressor

Cellular Component: nucleoplasm; intercellular bridge; cytoplasm; intracellular; nucleus

Molecular Function: protein binding; DNA binding; histone deacetylase binding; transcription cofactor activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; Ras protein signal transduction; positive regulation of transcription from RNA polymerase II promoter
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 Research Articles on RFXANK    1. ANKRA, RFXANK, and CIITA are novel targets of class IIa HDACs which may deacetylases play a role in regulating MHCII expression
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Pathways associated with RFXANK elisa kitDiseases associated with RFXANK elisa kit
 Products by Pathway  Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 Antigen Processing And Presentation Pathway antibodies  Antigen Processing And Presentation Pathway Diagram
 EGFR1 Signaling Pathway antibodies  EGFR1 Signaling Pathway Diagram
 Primary Immunodeficiency Pathway antibodies  Primary Immunodeficiency Pathway Diagram
 Primary Immunodeficiency Pathway antibodies  Primary Immunodeficiency Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
 Tuberculosis Pathway antibodies  Tuberculosis Pathway Diagram
 Disease Name  Pubmed Publications
 Immune System Diseases Antibodies  >21 publications with RFXANK and Immune System Diseases
 Bare lymphocyte syndrome 2 Antibodies  >3 publications with RFXANK and Bare lymphocyte syndrome 2
 Carcinoma Antibodies  >1 publications with RFXANK and Carcinoma
 Liver Diseases Antibodies  >1 publications with RFXANK and Liver Diseases
 Diarrhea Antibodies  >1 publications with RFXANK and Diarrhea
Organs/Tissues associated with RFXANK elisa kit
 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >2 publications with RFXANK and Lung
 Liver Antibodies  >1 publications with RFXANK and Liver
 Bone Marrow Antibodies  >1 publications with RFXANK and Bone Marrow
 Kidney Antibodies  >1 publications with RFXANK and Kidney
 Thymus Antibodies  >1 publications with RFXANK and Thymus
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