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SHBG elisa kit :: Mouse sex hormone-binding globulin ELISA Kit

Scan QR to view Datasheet Catalog #    MBS703219
Typical Testing Data/Standard Curve (for reference only)
Unit / Price
24-Strip-Wells (LIMIT 1)  /  $250 +1 FREE 8GB USB
48-Strip-Wells  /  $575 +1 FREE 8GB USB
96-Strip-Wells  /  $835 +1 FREE 8GB USB
5x96-Strip-Wells  /  $3,040 +3 FREE 8GB USB
10x96-Strip-Wells  /  $5,755 +7 FREE 8GB USB
 
 Go to:   rightarrow  Product Names   rightarrow Product Info   rightarrow Accession #s   rightarrow Product Desc   rightarrow Diseases/Tissues/Pathways   rightarrow Applications   rightarrow References 
 Product Name   

sex hormone-binding globulin (SHBG), ELISA Kit

 Also Known As   

Mouse sex hormone-binding globulin, SHBG ELISA Kit

 Product Synonym Names    Mouse sex hormone-binding globulin; SHBG ELISA Kit; ABP; MGC126834; MGC138391; SBP; TEBG; androgen binding protein; sex steroid-binding protein; testis-specific androgen-binding protein; testosterone-binding beta-globulin; testosterone-estradiol-binding; sex hormone-binding globulin
 Product Gene Name   

SHBG elisa kit

[Similar Products]
 Research Use Only    For Research Use Only. Not for use in diagnostic procedures.
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  Sample Manual Insert    Download PDF Manual View PDF Manual
 Request for Current Manual Insert    Request Current Manual
 MBS703219 Testing Data    Testing Data PDF
 3D Structure    ModBase 3D Structure for P97497
 Species Reactivity    Mouse
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 Specificity    This assay has high sensitivity and excellent specificity for detection of Mouse SHBG. No significant cross-reactivity or interference between Mouse SHBG and analogues was observed.
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 Detection Range    1.7 ng/ml-50 ng/ml
 Sensitivity    0.4 ng/ml
 Intra-assay Precision    Intra-assay Precision (Precision within an assay): CV% is less than 8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV% is less than 10%
Three samples of known concentration were tested in twenty assays to assess.
 Detection Wavelength    450 nm
 Sample Volume    50-100ul
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 Preparation and Storage    Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.
 ISO Certification    Manufactured in an ISO 9001:2008 Certified Laboratory.
 Product Note    Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
 Other Notes    Small volumes of SHBG elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
 Searchable Terms for SHBG purchase    MBS703219 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the sex hormone-binding globulin (SHBG) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range of 1.7 ng/ml-50 ng/ml in biological research samples containing SHBG, with an estimated sensitivity of 0.4 ng/ml. The ELISA analytical biochemical technique of the MBS703219 kit is based on SHBG antibody-SHBG antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SHBG antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SHBG. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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Related Product Information for SHBG elisa kit

   Introduction: Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to sex hormones, specifically testosterone and estradiol. Other steroid hormones such as progesterone, cortisol, and other corticosteroids are bound by transcortin. SHBG is produced by the liver cells and is released into the bloodstream. Other sites that produce SHBG are the brain, uterus, and placenta. In addition SHBG is produced by the testes; testes-produced SHBG is also called androgen-binding protein. The gene for SHBG is located on chromosome 17. SHBG levels appear to be controlled by a delicate balance of enhancing and inhibiting factors. Its level is decreased by high levels of insulin and insulin-like growth factor 1 (IGF-1). Also, high androgen and transcortin levels decrease SHBG, while high growth hormone, estrogen and thyroxine levels increase it. However, recent evidence suggests that it is the liver's production of fats that reduces SHBG levels, not any direct effect of insulin and specific genetic mechanisms have been found that do this.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to SHBG antibody. Standards or samples are then added to the appropriate microtiter plate wells with a Horseradish Peroxidase (HRP)-conjugated monoclonal antibody preparation specific for SHBG and incubated. Then substrate solution A and B are added to each well. Only those wells that contain SHBG, HRP-conjugated antibody will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of SHBG in the samples is then determined by comparing the O.D. of the samples to the standard curve.
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 Typical Testing Data/Standard Curve (for reference only) of SHBG elisa kit    SHBG elisa kit Typical Testing Data/Standard Curve (for reference only) image
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Sample Manual Insert of MBS703219. Click to request current manual
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NCBI/Uniprot data below describe general gene information for SHBG. It may not necessarily be applicable to this product.
 NCBI GI #    6755506
 NCBI GeneID    20415
 NCBI Accession #    NP_035497.1 [Other Products]
 NCBI GenBank Nucleotide #    NM_011367.2 [Other Products]
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 UniProt Primary Accession #    P97497 [Other Products]
 UniProt Secondary Accession #    Q0VB52 [Other Products]
 UniProt Related Accession #    P97497 [Other Products]
 Molecular Weight    44,816 Da
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 NCBI Official Full Name    sex hormone-binding globulin
 NCBI Official Synonym Full Names    sex hormone binding globulin
 NCBI Official Symbol    Shbg [Similar Products]
 NCBI Official Synonym Symbols   
ABP
[Similar Products]
 NCBI Protein Information    sex hormone-binding globulin; SBP; sex steroid-binding protein; testis-specific androgen-binding protein
 UniProt Protein Name    Sex hormone-binding globulin
 UniProt Synonym Protein Names   
Sex steroid-binding protein; SBP; Testis-specific androgen-binding protein; ABP
 Protein Family    Sex hormone-binding globulin
 UniProt Gene Name    Shbg [Similar Products]
 UniProt Synonym Gene Names    SHBG; SBP; ABP [Similar Products]
 UniProt Entry Name    SHBG_MOUSE
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 UniProt Comments for SHBG    Function: Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration
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 Research Articles on SHBG    1. monosaccharide-induced lipogenesis reduced hepatic HNF-4alpha levels, which in turn attenuated SHBG expression.
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 Precautions    All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
 Disclaimer    While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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Products associated with SHBG elisa kitPathways associated with SHBG elisa kit
 Reference Product  PubMed Publications
 Prl elisa kit  >200 publications with SHBG and Prl
 Esr1 elisa kit  >21 publications with SHBG and Esr1
 Igf1 elisa kit  >18 publications with SHBG and Igf1
 Gnrh1 elisa kit  >2 publications with SHBG and Gnrh1
 Serpina6 elisa kit  >2 publications with SHBG and Serpina6
 Lipc elisa kit  >1 publications with SHBG and Lipc
 Lep elisa kit  >1 publications with SHBG and Lep
 Products by Pathway  Pathway Diagram
 Nongenotropic Androgen Signaling Pathway antibodies  Nongenotropic Androgen Signaling Pathway Diagram
Diseases associated with SHBG elisa kitOrgans/Tissues associated with SHBG elisa kit
 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >541 publications with SHBG and Breast Neoplasms
 Congenital Abnormalities Antibodies  >354 publications with SHBG and Congenital Abnormalities
 Disorders of Sex Development Antibodies  >341 publications with SHBG and Disorders of Sex Development
 Urogenital Abnormalities Antibodies  >336 publications with SHBG and Urogenital Abnormalities
 Infertility Antibodies  >277 publications with SHBG and Infertility
 Prostatic Neoplasms Antibodies  >252 publications with SHBG and Prostatic Neoplasms
 Weight Loss Antibodies  >217 publications with SHBG and Weight Loss
 Diabetes Mellitus, Type 2 Antibodies  >196 publications with SHBG and Diabetes Mellitus, Type 2
 Hyperplasia Antibodies  >174 publications with SHBG and Hyperplasia
 Metabolic Syndrome X Antibodies  >160 publications with SHBG and Metabolic Syndrome X
 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >497 publications with SHBG and Liver
 Brain Antibodies  >314 publications with SHBG and Brain
 Testis Antibodies  >302 publications with SHBG and Testis
 Intestine Antibodies  >13 publications with SHBG and Intestine
 Eye Antibodies  >11 publications with SHBG and Eye
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